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Brain protein may be a target for fast-acting antidepressants

It takes weeks or months for the effect of most antidepressants to kick in, time that can feel like an eternity to those who need the drugs the most. But new research suggests that a protein called p11, previously shown to play a role in a person's susceptibility to depression, activates a serotonin receptor in the brain known for producing

25 Feb 2009

Scientists identify stem-cell genes that help form plant organs

Plant stem-cells are master cells located at the tip of the stem and are part of a structure called the shoot apical meristem (SAM).

24 Feb 2009

Scientists shed light on how proteins find their shapes

Researchers from the California Institute of Technology (Caltech) and the University of California at San Diego (UCSD) have brought together UCSD theoretical modeling and Caltech experimental data to show just how amino-acid chains might fold up into unique, three-dimensional functional proteins.

23 Feb 2009

Targeted nanospheres find, penetrate, then fuel burning of melanoma

Hollow gold nanospheres equipped with a targeting peptide find melanoma cells, penetrate them deeply, and then cook the tumor when bathed with near-infrared light. When heated with lasers, the actively targeted hollow gold nanospheres did eight times more damage to melanoma tumors in mice than did the same nanospheres that gathered less directly in the tumors.

23 Feb 2009

Radiolabeled nanoparticles boost PET-CT combination imaging

In an attempt to decrease the amount of cancer-targeting nanoparticle needed to image tumors, a team of investigators at the Massachusetts General Hospital and Harvard Medical School has developed a simple method for creating iron oxide nanoparticles labeled with 18F, a radioisotope that is easily detected using positron emission tomography (PET). The result is a nanoparticle that can be imaged using PET, computerized tomography (CT), and fluorescence imaging.

23 Feb 2009

Oxford Nanopore announces publication of DNA analysis paper

Oxford Nanopore Technologies ("Oxford Nanopore") today announced the publication of new research in Nature Nanotechnology, demonstrating accurate and continuous identification of DNA bases using nanopores.

From Oxford Nanopore Technologies 23 Feb 2009

New approach to dental visits may ease kids' fears

For many children, a trip to the doctor or dentist is a stressful experience.

22 Feb 2009

Human papillomavirus lesion identified with VELscope at dentist

Human papillomavirus (HPV) is a group of viruses that includes more than 100 different strains or types and is the most common sexually transmitted virus.

20 Feb 2009

An adjuvant chemotherapeutic agent in gastric cancer therapy

Peritoneal carcinomatosis can be thought of as a series of events that together form a peritoneal metastatic cascade.

18 Feb 2009

A stem cell bandage for your knee

Building on his previous work, Hollander and his team, which included Dr Wael Kafienah and Dr John Tarlton, announced in 2005 they had, for the first time ever, successfully grown human cartilage from a patient's own bone marrow stem cells.

18 Feb 2009

Dendritic cells as a new player in arteries and heart valves

In 1973, Ralph M. Steinman launched a new scientific discipline when he published his discovery of the dendritic cell, an odd-shaped player in the immune system.

16 Feb 2009

A view into the human body: the formation of cell organelles

Scientists at the RUB publish the results of their study in the Journal of Biological Chemistry.

10 Feb 2009

New microscope visualizes cells in 3D

University of Washington researchers have helped develop a new kind of microscope to visualize cells in three dimensions, an advance that could bring great progress in the field of early cancer detection.

9 Feb 2009

Researchers 'tighten' body's protective coating

A net with large holes won't catch small fish. Likewise, the microscopic fibers in the protective mucus coatings of the eyes, lungs, stomach or reproductive system naturally bundle together and allow the tiniest disease-causing bugs, allergens or pollutants to slip by.

8 Feb 2009

Gene-targeting approach for herpes treatment

A new therapy being developed at the University of Florida could, in time, produce another weapon for the fight against herpes.

3 Feb 2009

Peptide loaded gold nanospheres find, penetrate, then fuel burning of melanoma

Hollow gold nanospheres equipped with a targeting peptide find melanoma cells, penetrate them deeply, and then cook the tumor when bathed with near-infrared light, a research team led by scientists at The University of Texas M. D. Anderson Cancer Center reported in the Feb. 1 issue of Clinical Cancer Research.

2 Feb 2009