Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Study identifies the effects of malnutrition on patient survival after cardiac surgery

Nutrients are the structural components of food that the body needs to function properly. They are divided into macronutrients (proteins, fats, carbohydrates) and micronutrients (vitamins, provitamins, various minerals, and so on). Their shortage is called nutritional deficiency.

28 Dec 2020

Severity of COVID-19 correlates with the ratio of antibodies targeting crucial viral protein

COVID-19 antibodies preferentially target a different part of the virus in mild cases of COVID-19 than they do in severe cases, and wane significantly within several months of infection, according to a new study by researchers at Stanford Medicine.

24 Dec 2020

Modulating BST2 expression on blood stem cells may help regulate cell activation during chronic infections

When a person has an infection, the body activates immune responses to fight it. IFNγ is an inflammatory molecule produced by the immune system that helps fight infections.

23 Dec 2020

COVID-19 patients retain immunity against the virus for at least 8 months

Australian researchers have revealed - for the first time - that people who have been infected with the COVID-19 virus have immune memory to protect against reinfection for at least eight months.

22 Dec 2020

Trinity team uncovers mutations linked with early onset dementia

Scientists at Trinity College Dublin today announced a significant advance in our understanding of an early onset form of dementia that may also progress our understanding of conditions such as Alzheimer's disease.

22 Dec 2020

Immune-inflammatory mediators indicate that rejection and tissue injury can be avoided with drugs

Immune inflammatory mediators are critical in pathology, transplantation, and regenerative medicine, scientists report in The American Journal of Pathology

22 Dec 2020

Researchers have a promising lead on COVID-19 treatment

By taking a lesson from prostate cancer, researchers now have a promising lead on treatment for COVID-19. Two proteins, ACE2 and TMPRSS2, help the coronavirus gain entry and replicate within cells. TMPRSS2 is well-known to Arul Chinnaiyan, M.D., Ph.D. His lab discovered that TMPRSS2 fuses with the ETS gene to drive more than half of all prostate cancers. They also knew that TMPRSS2 was regulated by the androgen receptor.

21 Dec 2020

Community-based testing sites were key in minimizing exposure to COVID-19 virus

A new study looking at the results of testing children for COVID-19 through a Children's National Hospital community-based testing site found that one in four patients had a positive test.

21 Dec 2020

High altitude experts explain pneumolysis caused by COVID-19

The current COVID-19 pandemic has caused over 1 million deaths which can be attributed to its severe progressive pulmonary compromise.

21 Dec 2020

Absence of anti-tumor protein may cause resistance to EGFR-targeting therapies

The absence of a protein that works to prevent tumor formation may explain why some patients are resistant to a common cancer therapy, according to Penn State College of Medicine researchers.

21 Dec 2020

Researchers demonstrate potential preventive treatment for Crohn's disease

A potential preventive treatment for Crohn's disease, a form of inflammatory bowel disease, has been demonstrated in a mouse model and using immune-reactive T cells from patients with Crohn's disease.

21 Dec 2020

Arthritis drug may be effective in treating immunotherapy-related heart complication

A drug typically prescribed for rheumatoid arthritis may also be effective in treating a rare but potentially deadly heart complication some cancer patients experience after taking immunotherapies, according to a study published in Cancer Discovery and co-led by investigators at Vanderbilt University Medical Center.

21 Dec 2020

Detecting SARS-CoV-2 sequences in blood monocytes

A meeting with doctors from Wuhan presented a compelling observation to Professor Laura Manuelidis, MD, from the Yale Medical School early in 2020.

21 Dec 2020

Zika infection affects fetal retinal development during pregnancy but not after birth

While the SARS-CoV-2 virus has dominated the news this past year, researchers continue to study the health effects of the Zika virus, which has been reported in 86 countries globally.

18 Dec 2020

Errant DNA triggers immune system response against cancer

DNA that ends up where it doesn't belong in cancer cells can unleash an immune response that makes tumors more susceptible to immunotherapy, the results of two UT Southwestern studies indicate.

17 Dec 2020

Oral contraceptives offer a protective effect against common gynecological cancers

A comprehensive study from Uppsala University, involving more than 250,000 women, shows that oral contraceptive use protects against ovarian and endometrial cancer. The protective effect remains for several decades after discontinuing the use. The study is published in the journal Cancer Research.

17 Dec 2020

Mother's diet while breastfeeding can shape the profile of human milk oligosaccharides

Research has shown that human milk is the optimal nutrition source for neonates and infants. It confers protection against both immediately life-threatening infant diseases such as necrotizing enterocolitis, as well as later onset diseases in adults, like obesity, diabetes and inflammatory bowel disease.

16 Dec 2020

Pathology News and Research

Further Reading

Study identifies the effects of malnutrition on patient survival after cardiac surgery

Severity of COVID-19 correlates with the ratio of antibodies targeting crucial viral protein

Modulating BST2 expression on blood stem cells may help regulate cell activation during chronic infections

COVID-19 patients retain immunity against the virus for at least 8 months

Trinity team uncovers mutations linked with early onset dementia

Immune-inflammatory mediators indicate that rejection and tissue injury can be avoided with drugs

Researchers have a promising lead on COVID-19 treatment

Community-based testing sites were key in minimizing exposure to COVID-19 virus

High altitude experts explain pneumolysis caused by COVID-19

Absence of anti-tumor protein may cause resistance to EGFR-targeting therapies

Researchers demonstrate potential preventive treatment for Crohn's disease

Arthritis drug may be effective in treating immunotherapy-related heart complication

Detecting SARS-CoV-2 sequences in blood monocytes

Zika infection affects fetal retinal development during pregnancy but not after birth

Errant DNA triggers immune system response against cancer

Oral contraceptives offer a protective effect against common gynecological cancers

Mother's diet while breastfeeding can shape the profile of human milk oligosaccharides

Scientists discover how a 'sociable' protein can hold clues about Alzheimer's origin

Researchers identify new immune cell that acts as major driver of breast cancer growth

Researchers discover and describe two fungal species for the first time

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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