Therapeutics News and Research

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Novel peptide helps prevent seizures, protects neurons in research models of both Alzheimer's and epilepsy

A novel peptide augments the brain's natural mechanism to help prevent seizures and protect neurons in research models of both Alzheimer's and epilepsy, scientists report.

16 Aug 2022

Rapid and efficient strategy for the development and design of SARS-CoV-2 neutralizing humanized nanobody constructs

Researchers developed humanized nanobodies that neutralize SARS-CoV-2.

16 Aug 2022

Next generation mRNA vaccines exhibit excellent protective and therapeutic effects

Researchers around the world have been working for years on developing vaccines against different types of cancer, but without much success. Now, Tufts School of Engineering researchers think they have found one that does work. They have devised a method of targeting cancer in mice with a vaccine that is so strong and precise, it eliminates tumors and even prevents their recurrence.

16 Aug 2022

Financial incentives from pharma companies can influence how vision care practitioners prescribe branded eyedrops

In a lookback study of prescribing patterns among thousands of American ophthalmologists and optometrists, Johns Hopkins Medicine researchers concluded that eye doctors who receive even small financial incentives from pharmaceutical companies, such as free food, sponsored travel to attend meetings or consulting fees, are up to twice as likely to prescribe the companies' brand name eyedrops for glaucoma instead of cheaper generic versions.

15 Aug 2022

Study paves new way to develop a predictive biomarker for TRAIL therapy

A cytokine named TRAIL binds to TRAIL receptors and kills cancer cells, but not normal cells. Therefore, various anticancer drugs targeting TRAIL receptors have been developed and gained great attention as a promising cancer therapeutics, but a certain population of cancer patients does not respond to the therapy.

15 Aug 2022

Scientists explore nanomolar inhibition of SARS-CoV-2 infection via unmodified peptide targeting spike protein pre-hairpin intermediate

In a new study, scientists identified an unmodified peptide addressing pre-hairpin spike (S) protein intermediate inhibiting SARS-CoV-2 infection.

15 Aug 2022

American Heart Association and Cardiovascular Research Foundation join forces to produce joint education programs

Two leaders in cardiovascular disease science, research and education, the American Heart Association (Association) and the Cardiovascular Research Foundation (CRF), are joining forces to strengthen and expand educational opportunities focused on advancing the latest research in cardiovascular disease and interventional therapies.

15 Aug 2022

In monkeys, spike-based vaccines produce some immunity based on CD8 T-cells

Scientists evaluate the role of CD8+ T-cells in vaccine protection against SARS-CoV-2 infection in rhesus macaques.

14 Aug 2022

Mount Sinai and Regeneron Genetics Center launch a new human genome sequencing research project

Mount Sinai Health System and the Icahn School of Medicine at Mount Sinai have launched a new human genome sequencing research project called the Mount Sinai Million Health Discoveries Program with the Regeneron Genetics Center (RGC), part of the industry-leading, New York-based biotechnology company Regeneron.

12 Aug 2022

How should we react to the global monkeypox outbreak?

In a new study, researchers assessed the various aspects of the global monkeypox outbreak.

12 Aug 2022

Big pharma went all in to kill drug pricing negotiations

For decades, the drug industry has yelled bloody murder each time Congress considered a regulatory measure that threatened its profits.

12 Aug 2022

Depression may be the strongest predictor of COVID-19-associated persistent brain fog, study finds

In a new study, researchers assessed the prevalence of cognitive complaints in COVID-19 patients and explored the factors associated with brain fog after one year of COVID-19 diagnosis.

12 Aug 2022

Novel zoonotic Langya virus identified in China

Scientists discuss their discovery of the novel Langya henipavirus in eastern China.

11 Aug 2022

Researchers identify genes that become active when carotid plaque rupture leads to a stroke

Researchers at Ochsner Health and Tulane University School of Medicine have identified the genes that become active in carotid arteries when plaque rupture causes a stroke.

11 Aug 2022

Study identifies multiple pathways adopted by SARS-CoV-2 to develop resistance to nirmatrelvir

Researchers demonstrated multiple routes SARS-CoV-2 might take to develop high-level resistance to nirmatrelvir, an oral antiviral targeting the 3C-like protease (3CLpro) of SARS-CoV-2.

11 Aug 2022

Crying out for new disease diagnoses

In this interview, we speak to Dr. Fei Liu and Dr. Luke P. Lee about their new iTears platform and how it could help to diagnose disease from tears.

11 Aug 2022

Newly designed nanoparticles target the body’s immune cells to turn them against cancer

Scientists of the department of Advanced Organ Bioengineering and Therapeutics (Faculty of S&T, TechMed Centre) recently published a novel cancer immune therapy in the scientific journal Nature Communications.

11 Aug 2022

New computation-guided approach to identify small molecule corrector drugs for p53 hotspot mutations

A new study, led by researchers from the University of California, Irvine and the University of California, San Diego, reveals a new computation-guided approach to identify small molecules that can restore aspects of wild-type p53 tumor suppression function to mutated p53, which play an important role in many human cancers.

11 Aug 2022

Monoclonal antibody decreases asthma attacks by 27% in children and adolescents of color

A monoclonal antibody, mepolizumab, decreased asthma attacks by 27% in Black and Hispanic children and adolescents who have a form of severe asthma, are prone to asthma attacks and live in low-income urban neighborhoods, a National Institutes of Health clinical trial has found.

10 Aug 2022

Review of natural products with promising anti-SARS-CoV-2 potential

In a new study, researchers reviewed existing literature on naturally active products with therapeutic efficacy against SARS-CoV-2.

10 Aug 2022

Therapeutics News and Research

Novel peptide helps prevent seizures, protects neurons in research models of both Alzheimer's and epilepsy

Rapid and efficient strategy for the development and design of SARS-CoV-2 neutralizing humanized nanobody constructs

Next generation mRNA vaccines exhibit excellent protective and therapeutic effects

Financial incentives from pharma companies can influence how vision care practitioners prescribe branded eyedrops

Study paves new way to develop a predictive biomarker for TRAIL therapy

Scientists explore nanomolar inhibition of SARS-CoV-2 infection via unmodified peptide targeting spike protein pre-hairpin intermediate

American Heart Association and Cardiovascular Research Foundation join forces to produce joint education programs

In monkeys, spike-based vaccines produce some immunity based on CD8 T-cells

Mount Sinai and Regeneron Genetics Center launch a new human genome sequencing research project

How should we react to the global monkeypox outbreak?

Big pharma went all in to kill drug pricing negotiations

Depression may be the strongest predictor of COVID-19-associated persistent brain fog, study finds

Novel zoonotic Langya virus identified in China

Researchers identify genes that become active when carotid plaque rupture leads to a stroke

Study identifies multiple pathways adopted by SARS-CoV-2 to develop resistance to nirmatrelvir

Crying out for new disease diagnoses

Newly designed nanoparticles target the body’s immune cells to turn them against cancer

New computation-guided approach to identify small molecule corrector drugs for p53 hotspot mutations

Monoclonal antibody decreases asthma attacks by 27% in children and adolescents of color

Review of natural products with promising anti-SARS-CoV-2 potential

Industry Focus eBook - Microbiome (1st edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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