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The human brain is the center of the human nervous system and is a highly complex organ. Enclosed in the cranium, it has the same general structure as the brains of other mammals, but is over three times as large as the brain of a typical mammal with an equivalent body size.

FDA clears Inhibikase IkT-001 Phase II trial to treat JCV infection in multiple sclerosis patients

Inhibikase Therapeutics, Inc., an emerging leader in infectious disease, announced today that it has received FDA clearance to commence a Phase II proof-of-concept trial for its lead compound IkT-001. IkT-001, a host-directed kinase inhibitor, is intended to clear JC polyomavirus (JCV) infection, the causative agent of Progressive Multifocal Leukoencephalopathy (PML).

17 Aug 2011

Moderate social drinking reduces risk of dementia and cognitive impairment

Moderate social drinking significantly reduces the risk of dementia and cognitive impairment, according to an analysis of 143 studies by Loyola University Chicago Stritch School of Medicine researchers.

17 Aug 2011

FDA approves two new strengths of Lupron Depot-PED for central precocious puberty

Abbott announced today that the U.S. Food and Drug Administration has approved two new strengths for three-month administration of Lupron Depot-PED (leuprolide acetate for depot suspension) for the treatment of children with central precocious puberty (CPP).

17 Aug 2011

Fluctuations in brain signals explained: Spontaneous electrical background rhythms in the brain influence fMRI

Until now, brain scans obtained using fMRI – one of the most important imaging methods in use today – have been affected by fluctuations in the brain activity measured which could not be explained. Researchers at the Max Planck Institute for Human Cognitive and Brain Sciences in Leipzig and the Charité in Berlin have now shown that certain electric background rhythms in the brain, known as Alpha oscillations, alter the fMRI signal obtained with visual stimuli. To do this, they used a new approach in which quickly changing brain activity, which cannot be captured by the scanner, was measured using

16 Aug 2011

LYSOGENE launches the first gene therapy clinical trials in Sanfilippo disease

LYSOGENE announces the authorization by AFSSAPS (the French Agency for the Safety of Health Products) and by the Ethical Review Board of SAF-301, its leading intra-cerebral gene therapy phase I/II clinical trial aiming at treating Sanfilippo Type A Syndrome.

16 Aug 2011

Study investigates autism spectrum disorder, sibling recurrence

The risk that an infant with an older sibling with autism also will develop the disorder, previously estimated at between 3 and 10 percent, is substantially higher at approximately 19 percent, a large, international, multi-site study led by researchers at the UC Davis MIND Institute has found.

16 Aug 2011

Modified Cdk5 enzyme triggers damage to nerve cell connections in human Alzheimer's brains

Alzheimer's disease is characterized by abnormal proteins that stick together in little globs, disrupting cognitive function. These sticky proteins are mostly made up of beta-amyloid peptide. A better understanding of these proteins, how they form, and how they affect brain function will no doubt improve the diagnosis and treatment of Alzheimer's disease.

16 Aug 2011

Biochemist develops polymer material to convert precursor cells into functional neurones

Nervous system diseases are especially difficult to treat, as it is not easy to replace the parts of the neural puzzle which are damaged. The key is in developing functional neurons from in vitro-treated, cells but for this it is essential that the support on which these cells are based simulate the characteristics of the nervous system.

16 Aug 2011

Green tea shows promise against two types of tumors, HHS

A compound found in green tea shows great promise for the development of drugs to treat two types of tumors and a deadly congenital disease. The discovery is the result of research led by Principal Investigator, Dr. Thomas Smith at The Donald Danforth Plant Science Center and his colleagues at The Children's Hospital of Philadelphia.

16 Aug 2011

Gene therapy cocktail can treat inherited diseases with 'misfolded' proteins

In a kind of molecular gymnastics, scientists at the University of North Carolina at Chapel Hill School of Medicine have devised a gene therapy cocktail that has the potential to treat some inherited diseases associated with "misfolded" proteins.

16 Aug 2011

Study explores how some cognitive strategies and abilities boost self-efficacy

Sticking with an exercise routine means being able to overcome the obstacles that invariably arise. A key to success is having the confidence that you can do it, researchers report. A new study explores how some cognitive strategies and abilities increase this "situation-specific self-confidence," a quality the researchers call "self-efficacy."

16 Aug 2011

AHRQ's new Spanish-language guide on heart medications

A free, illustrated easy-to-read pamphlet that compares drugs for preventing heart attacks, heart failure or strokes in people with stable coronary heart disease is one of six new Spanish-language publications from HHS' Agency for Healthcare Research and Quality that help patients compare treatments for common illnesses.

16 Aug 2011

Survey: 35% of people in the UK fear cancer more than other life-threatening conditions

More than a third of people in the UK fear cancer more than other life-threatening conditions - such as Alzheimer's, stroke and heart disease according to a Cancer Research UK survey.

16 Aug 2011

Regular exercise could help prevent brain damage linked with Alzheimer's

Regular exercise could help prevent brain damage associated with neurodegenerative diseases like Alzheimer's, according to research published this month in Elsevier's journal Brain, Behavior, and Immunity.

16 Aug 2011

MRI scans show children of depressed mothers have enlarged amygdala

Researchers think that brains are sensitive to the quality of child care, according to a study that was directed by Dr. Sonia Lupien and her colleagues from the University of Montreal published today in the Proceedings of the National Academy of Sciences.

16 Aug 2011

New role for harmonin protein in Usher syndrome

University of Iowa scientists have discovered a new role for a protein that is mutated in Usher syndrome, one of the most common forms of deaf-blindness in humans. The findings, which were published Aug. 8 in Nature Neuroscience, may help explain why this mutation causes the most severe form of the condition.

16 Aug 2011

Alpha-synuclein protein key to Parkinson's has likely been mischaracterized

A new study finds that a protein key to Parkinson's disease has likely been mischaracterized. The protein, alpha-synuclein, appears to have a radically different structure in healthy cells than previously thought, challenging existing disease paradigms and suggesting a new therapeutic approach.

16 Aug 2011

Addiction to tanning

A new study reveals addiction of a new kind – addiction to tanning. Researchers have believed for several years that tanners exhibit similar behavior to alcoholics and drug addicts.

15 Aug 2011

Arrythmia drug may work in stroke prevention: Study

The latest research has revealed that a new drug for treating people with an irregular heartbeat has fewer side effects than the standard treatment and is just as good at cutting the risk of stroke. Rivaroxaban, which is easier for people to take, is as effective as warfarin at preventing blood clots and thus lowering the risk of stroke for patients with atrial fibrillation say researchers.

15 Aug 2011

UH, Centerre Healthcare partner to construct new rehabilitation hospital in Beachwood

University Hospitals (UH) in Cleveland, OH, and Nashville-based Centerre Healthcare Corporation announced today a joint venture to construct a comprehensive inpatient rehabilitation hospital in Beachwood, OH.

12 Aug 2011