Clinical Trial News and Research

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What are the parallel effects of exercise on cardiometabolic and mental health in children with an excess of adiposity?

Researchers performed a secondary analysis of the ActiveBrains randomized clinical trial (RCT) to look at how a 20-week exercise program affected child health.

2 Aug 2023

Does long-term, daily low-dose aspirin treatment affect the incidence of stroke or intracerebral bleeding?

Researchers found that older adults who took aspirin had a 38% higher risk of intracranial bleeding.

2 Aug 2023

Intranasally administered SARS-CoV-2 RBD-based nanoparticle vaccine provides protection against lung pathology and viral load

In a recent study, researchers working at Ohio State University in the United States of America (USA) developed an intranasal subunit vaccine.

2 Aug 2023

Rapid test could determine the existence of a key driver of severe asthma

Based on decades of work to uncover the underlying mechanisms of asthma and other respiratory conditions, researchers at McMaster University and St. Joseph's Healthcare Hamilton have produced a simple, rapid test that can identify the presence of a key driver of severe asthma.

2 Aug 2023

Non-invasive brain stimulation shows promise for treating ADHD in children

Non-invasive brain stimulation, combined with cognitive training, could significantly improve symptoms of attention deficit hyperactivity disorder (ADHD) in children, according to new research jointly led by the University of Surrey and the Hebrew University of Jerusalem.

1 Aug 2023

Phase 1 clinical trial underway to test City of Hope-developed cancer treatment

Researchers at City of Hope, one of the largest cancer research and treatment organizations in the United States, today published a new study explaining how they took a protein once thought to be too challenging for targeted therapy, proliferating cell nuclear antigen (PCNA), and developed a targeted chemotherapy that appears to annihilate all solid tumors in preclinical research.

1 Aug 2023

CHLA researcher to lead a new study on liquid biopsy for diagnosing ocular cancer in children

Just a handful of years ago, retinoblastoma had the medical field stumped. This pediatric eye cancer cannot be directly biopsied, which means clinicians must diagnose the disease by visual examination and imaging.

1 Aug 2023

Kombucha may help lower blood sugar levels in people with type 2 diabetes

People with type-II diabetes who drank the fermented tea drink kombucha for four weeks had lower fasting blood glucose levels compared to when they consumed a similar-tasting placebo beverage, according to results from a clinical trial conducted by researchers at Georgetown University's School of Health, the University of Nebraska-Lincoln and MedStar Health.

1 Aug 2023

Study highlights metabolite targets for depression prevention that are easily modifiable through diet interventions

Researchers used a UHPLC and mass spectrometry-based Metabolon platform to identify and characterize circulating metabolites associated with depression.

1 Aug 2023

IN8bio opens new cancer research lab in Birmingham's Pepper Place

Birmingham's Pepper Place has a striking new addition to its teeming farmers' market and noted food offerings - a multimillion-dollar cancer research laboratory.

1 Aug 2023

RSV vaccines for older adults: 2023 ACIP recommendations

A recent report published in Morbidity and Mortality Weekly Report provided clinical guidance on Respiratory syncytial virus (RSV) vaccines for adults ≥60 years.

1 Aug 2023

Two new subtypes of HPV+ head and neck cancers identified

Cases of human papillomavirus (HPV)-associated cancers of the head and neck, known as head and neck squamous cell carcinoma (HNSCC), are rapidly increasing throughout the United States.

31 Jul 2023

NIH launches and opens enrollment for phase 2 clinical trials to evaluate long COVID treatments

Today, the National Institutes of Health launched and is opening enrollment for phase 2 clinical trials that will evaluate at least four potential treatments for long COVID, with additional clinical trials to test at least seven more treatments expected in the coming months.

31 Jul 2023

Tulane study finds potential treatment for eosinophilic esophagitis

A new study from Tulane University has identified a new treatment for a chronic immune system disease that can prevent children from eating.

31 Jul 2023

Stem cells offer new hope for Crohn's disease treatment

Research from Ann & Robert H. Lurie Children's Hospital of Chicago found that direct injection of neonatal mesenchymal stem cells, derived from heart tissue discarded during surgery, reduces intestinal inflammation and promotes wound healing in a mouse model of Crohn's disease-like ileitis, an illness marked by chronic intestinal inflammation and progressive tissue damage.

28 Jul 2023

MUSC study to determine optimal dose of transcranial magnetic stimulation for MCI

With more than $3.7 million in funding from the National Institute on Aging, Medical University of South Carolina neuropsychologist Andreana Benitez, Ph.D., of the Department of Neurology in the College of Medicine will lead a phase II clinical trial to determine the optimal dose of transcranial magnetic stimulation, or TMS, needed to improve symptoms for patients with depression and mild cognitive impairment, or MCI.

28 Jul 2023

New class of antibody could benefit patients with treatment-resistant cancers

A Cancer Research UK-funded clinical trial has shown, for the first time, that a new class of antibody could benefit cancer patients whose existing treatments have stopped working.

28 Jul 2023

Broad-spectrum influenza vaccine candidate shows safety, immunogenicity data across three dose levels

Osivax, a biopharmaceutical company developing vaccines to provide broad-spectrum protection against highly mutating infectious viruses, today announced that The Lancet Infectious Diseases published results from the company's OVX836-003 study under the title, "Immunogenicity, safety and preliminary efficacy evaluation of OVX836, a nucleoprotein-based universal influenza A vaccine candidate: randomized, double-blind placebo-controlled, Phase 2a trial."

27 Jul 2023

Long-term commitment to MIND diet needed for reaping brain health benefits

New research shows the importance of long-term commitment to the MIND diet for reaping the greatest benefit to brain health.

27 Jul 2023

Susan G. Komen announces fourth grant for metastatic breast cancer research

Susan G. Komen, the world's leading breast cancer organization, announced the fourth MBC-focused research grant supported through the Komen Metastatic Breast Cancer Collaborative Research Initiative (MBCCRI), a collaboration between Komen, Duke Cancer Institute and the University of North Carolina Lineberger Comprehensive Cancer Center, which pairs researchers from each of the organizations to work together and address significant gaps in our knowledge about MBC to advance patient care and improve patient outcomes.

27 Jul 2023

Clinical Trial News and Research

What are the parallel effects of exercise on cardiometabolic and mental health in children with an excess of adiposity?

Does long-term, daily low-dose aspirin treatment affect the incidence of stroke or intracerebral bleeding?

Intranasally administered SARS-CoV-2 RBD-based nanoparticle vaccine provides protection against lung pathology and viral load

Rapid test could determine the existence of a key driver of severe asthma

Non-invasive brain stimulation shows promise for treating ADHD in children

Phase 1 clinical trial underway to test City of Hope-developed cancer treatment

CHLA researcher to lead a new study on liquid biopsy for diagnosing ocular cancer in children

Kombucha may help lower blood sugar levels in people with type 2 diabetes

Study highlights metabolite targets for depression prevention that are easily modifiable through diet interventions

IN8bio opens new cancer research lab in Birmingham's Pepper Place

RSV vaccines for older adults: 2023 ACIP recommendations

Two new subtypes of HPV+ head and neck cancers identified

NIH launches and opens enrollment for phase 2 clinical trials to evaluate long COVID treatments

Tulane study finds potential treatment for eosinophilic esophagitis

Stem cells offer new hope for Crohn's disease treatment

MUSC study to determine optimal dose of transcranial magnetic stimulation for MCI

New class of antibody could benefit patients with treatment-resistant cancers

Broad-spectrum influenza vaccine candidate shows safety, immunogenicity data across three dose levels

Long-term commitment to MIND diet needed for reaping brain health benefits

Susan G. Komen announces fourth grant for metastatic breast cancer research

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