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Photobiomodulation in Alzheimer's mouse model falls short in preventive impact

Study assesses the effectiveness of photobiomodulation (PBM) treatment in a mouse model of Alzheimer's disease and finds no significant impact on behavioral performance or neurodegeneration, suggesting the need for further research into PBM's therapeutic potential.

16 Nov 2023

Oral antibiotic taken once-daily for six months reduces risk of developing drug-resistant TB

Two landmark clinical trials reported today at the Union meeting showed that an oral antibiotic taken for six months once-daily substantially reduced the risk of developing drug-resistant TB.

16 Nov 2023

Exploring the dual role of nirmatrelvir and bisphosphonates in COVID-19 treatment and immunity

Review examines nirmatrelvir and bisphosphonates in treating COVID-19, revealing their impact on SARS-CoV-2-specific adaptive immunity and potential to mitigate severe infections, highlighting the need for balanced long-term immunity management.

16 Nov 2023

AI model predicts patient outcomes across multiple cancer types

Investigators from the UCLA Health Jonsson Comprehensive Cancer Center have developed an artificial intelligence (AI) model based on epigenetic factors that is able to predict patient outcomes successfully across multiple cancer types.

16 Nov 2023

Tackling Antimicrobial Resistance Together: A Conversation with Dr. Beverley Isherwood

An interview with Dr Beverley Isherwood.

16 Nov 2023

New study reveals turmeric and Tinospora Cordifolia reduce liver injury risk in TB patients

The effectiveness of herbs and alternative medicines in preventing liver injury induced by anti-tuberculosis (anti-TB) drugs.

16 Nov 2023

Curcumin boosts brain delivery of HIV drug, curbing inflammation and oxidative stress

Study shows curcumin enhances antiretroviral delivery and reduces inflammation and oxidative stress in HIV, offering potential improvements in treating HIV-associated neurocognitive disorders.

16 Nov 2023

Fecal microbiota transplantation boosts survival in metastatic colorectal cancer treatment

A recent study in eClinicalMedicine found that fecal microbiota transplantation, combined with fruquintinib and tislelizumab, significantly improved survival rates in patients with microsatellite stable metastatic colorectal cancer, showing manageable safety and notable increases in progression-free and overall survival.

15 Nov 2023

Electroconvulsive therapy alleviates depression symptoms by increasing aperiodic activity

Electroconvulsive therapy (ECT), formerly known as electroshock therapy, involves inducing a brief seizure in the brain using controlled doses of electricity.

15 Nov 2023

Research opens the door to a potential treatment strategy for certain advanced prostate cancers

Epigenetic changes can cause prostate cancer to resist treatment by switching genes on or off. One epigenetic mechanism tags genes with DNA methylation marks.

15 Nov 2023

New evidence-based clinical practice guidelines to address peripartum depression

Pregnancy and the first year postpartum - referred to as the peripartum period - are a period of tremendous physiological, psychological, and social changes in a woman's life.

15 Nov 2023

Cannabis shows promise in easing endometriosis pain, new research suggests

The Journal of Clinical Medicine review explores cannabis as a self-management strategy for endometriosis pain, revealing its potential to reduce gut inflammation and improve gut permeability, thereby alleviating bloating and suppressing pain through interactions with the endocannabinoid system and gut microbiota.

14 Nov 2023

Anti-inflammatory medication does not reduce frailty risk in adults with atherosclerosis

Frailty is a common condition in older populations that increases the risk of adverse health outcomes and mortality.

14 Nov 2023

Gene therapy for rare diseases: A decade of progress and remaining challenges

A new review article in the peer-reviewed journal Human Gene Therapy summarizes the significant milestones in the development of gene therapy medicinal products that have facilitated the treatment of a significant number of rare diseases.

14 Nov 2023

New vaccine against Strep A could drastically cut antibiotic use for sore throats, study suggests

Study predicts that a vaccine against group A Streptococcus (Strep A) could significantly reduce antibiotic prescriptions for sore throat, potentially leading to a 33% decrease in global antibiotic use for this condition.

14 Nov 2023

Novel cancer immunotherapy compound degrades an enzyme found in cancer cells and T cells

Researchers in Purdue University's College of Pharmacy are leveraging the dual roles played by an enzyme found in both cancer cells and T cells to create a novel cancer immunotherapy compound.

14 Nov 2023

Study uses cellulose sheets to map body's extracellular vesicles, unlocking disease insights

Study demonstrates the use of cellulose nanofiber sheets for spatial analysis of extracellular vesicles, revealing their geographical heterogeneity in the human body, which could advance the understanding and treatment of diseases.

14 Nov 2023

High-dose CBD fails to relieve pain in knee osteoarthritis patients

Cannabidiol (CBD) is marketed by some suppliers as a painkiller, e.g. for osteoarthritis of the knee. Animal experiments have shown that the substance, which is extracted from the hemp plant, has an anti-inflammatory and pain-relieving effect in arthritis.

14 Nov 2023

Genetic test for antidepressants could save millions and improve patient outcomes

A special kind of genetic test that helps determine the best antidepressant for patients with moderate-to-severe depression could generate substantive health system savings and greatly improve patient outcomes, according to new research from the University of British Columbia.

14 Nov 2023

New gel delivery system overcomes challenges of intratumoral cancer immunotherapy

Intratumoral therapy – in which cancer drugs are injected directly into tumors – is a promising treatment option for solid cancers but has shown limited success in clinical trials due to an inability to precisely deliver the drug and because most immunotherapies quickly dissipate from the site of injection.

13 Nov 2023

Efficacy News and Research

Photobiomodulation in Alzheimer's mouse model falls short in preventive impact

Oral antibiotic taken once-daily for six months reduces risk of developing drug-resistant TB

Exploring the dual role of nirmatrelvir and bisphosphonates in COVID-19 treatment and immunity

AI model predicts patient outcomes across multiple cancer types

Tackling Antimicrobial Resistance Together: A Conversation with Dr. Beverley Isherwood

New study reveals turmeric and Tinospora Cordifolia reduce liver injury risk in TB patients

Curcumin boosts brain delivery of HIV drug, curbing inflammation and oxidative stress

Fecal microbiota transplantation boosts survival in metastatic colorectal cancer treatment

Electroconvulsive therapy alleviates depression symptoms by increasing aperiodic activity

Research opens the door to a potential treatment strategy for certain advanced prostate cancers

New evidence-based clinical practice guidelines to address peripartum depression

Cannabis shows promise in easing endometriosis pain, new research suggests

Anti-inflammatory medication does not reduce frailty risk in adults with atherosclerosis

Gene therapy for rare diseases: A decade of progress and remaining challenges

New vaccine against Strep A could drastically cut antibiotic use for sore throats, study suggests

Novel cancer immunotherapy compound degrades an enzyme found in cancer cells and T cells

Study uses cellulose sheets to map body's extracellular vesicles, unlocking disease insights

High-dose CBD fails to relieve pain in knee osteoarthritis patients

Genetic test for antidepressants could save millions and improve patient outcomes

New gel delivery system overcomes challenges of intratumoral cancer immunotherapy

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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