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Study demonstrates that intra-host SARS-CoV-2 variants with reduced infectivity are developed during infection

A new paper discusses the appearance of quasi-species in a single host with prolonged infection, with different rates of infectivity and sensitivity to neutralization by antibodies elicited by the Pfizer vaccine or those present in convalescent plasma.

17 Jan 2022

Monitoring rodents for SARS-CoV-2 and other coronaviruses, Hong Kong

A new study published in the Centers for Disease Control and Prevention’s Emerging Infectious Diseases journal has hypothesized that locations with positive SARS-CoV-2 in sewage could be used as potential surveillance targets to analyze if pestiferous urban rodents shed SARS-CoV-2 into the environment.

16 Jan 2022

Study reveals factors responsible for increased risk of aerosol transmission for SARS-CoV-2 Delta and Omicron

A new study describes the expected distribution of viral emission of COVID-19 by an infected population of people who were either silent, speaking softly, or loudly, to determine factors influencing risks of viral transmission.

14 Jan 2022

Similarities and dissimilarities in immune responses and metabolism in SARS-CoV-2 and HIV-1 infections

A new study, posted to the bioRxiv* preprint server, has developed a single-cell atlas that presents the shared and distinct immune responses and metabolism following SARS-CoV-2 and HIV-1 infections.

13 Jan 2022

Insignificant homology of SARS-CoV-2 spike sequences to myocarditis-associated antigens

Researchers determine whether sequences within SARS-CoV-2 could lead to an immune response to autoantigens associated with autoimmune myocarditis.

13 Jan 2022

Virus-like particles as delivery vehicles for gene-editing

Scientists deliver gene-editing proteins through the use of engineered virus-like particles, which mediated efficient base editing both in vitro and in vivo.

13 Jan 2022

Analysis of COVID vaccine breakthrough infections in highly vaccinated Israel

Researchers evaluated and modeled age-structured cases of SARS-CoV-2 infection, SARS-CoV-2 vaccination coverage, and breakthrough infections.

13 Jan 2022

Investigating the presence of human rRNA in the SARS-CoV-2 genome

In a new study, a team of researchers investigated the existence of SARS-CoV-2-host chimeric RNA and described two novel human-derived genomic insertions present in the circulating variants of SARS-CoV-2.

13 Jan 2022

Forecasting seasonal SARS-CoV-2 mutations

In a study published in Science Translational Medicine, researchers have been trying to create a technique to predict which of these mutations will spread.

13 Jan 2022

Lack of evidence cross-reactive adaptive immune response is mechanism underlying COVID vaccine-induced myocarditis

Recently, the researchers from the USA, in their study published in the journal EBioMedicine, have conducted a sequence identity comparison and 3D protein structure comparison between the SARS-CoV-2 spike protein-derived peptides/protein and myocarditis-associated antigens and have found no significant enrichment in the frequency of spike-derived peptides similar to myocarditis-associated antigens that could have resulted in adaptive autoimmune responses leading to myocarditis.

12 Jan 2022

Severity of menopause symptoms linked to a woman's cognitive performance

Menopause is often accompanied by an array of symptoms that can detract from a woman's quality of life. A new study suggests that the severity of some of those symptoms - especially depression and sexual dysfunction - were linked to a woman's cognitive performance.

12 Jan 2022

New method for monitoring circulating SARS-CoV-2 variants and detecting new ones

To understand and act early and appropriately to emerging variants of concern, researchers have explored the possibility of having a variant-agnostic detection assay.

12 Jan 2022

A common cold may boost the immune system against COVID-19

A recent groundbreaking research paper published in the journal Nature Communications reveals the association of circulating SARS-CoV-2-specific T cells at exposure with lack of infection – implying the protective role for cross-reactive immune T cells in coronavirus disease 2019 (COVID-19) and opening the door for second-generation vaccines that could circumvent spike-antibody immune escape variants.

11 Jan 2022

Decoding imagined language to treat people suffering from aphasia

What if it were possible to decode the internal language of individuals deprived of the ability to express themselves? This is the objective of a team of neuroscientists from the University of Geneva (UNIGE) and the University Hospitals of Geneva.

11 Jan 2022

International study offers a clearer picture of COVID-19's impact on children

A new international study offers a clearer picture of the impact of COVID-19 infection and the risk of severe outcomes on young people around the world.

11 Jan 2022

Developing a 'fingerprint' test that could diagnose Alzheimer’s early

In this interview, we spoke to Dr. Cynthia McMurray about her latest research into Alzheimer's disease.

11 Jan 2022

Study finds T cell response mostly conserved against SARS-CoV-2 Omicron variant following infection or vaccination

A new preprint examines the extent of protection offered by T cell responses to primary vaccination and/or natural infection with the virus.

11 Jan 2022

Higher olive oil consumption linked with lower risk of cardiovascular disease, cancer mortality

Consuming more than 7 grams (>1/2 tablespoon) of olive oil per day is associated with lower risk of cardiovascular disease mortality, cancer mortality, neurodegenerative disease mortality and respiratory disease mortality, according to a study publishing today in the Journal of the American College of Cardiology.

10 Jan 2022

Mapping regulatory T-cell populations in COVID-19 patients

In a new study, researchers used mass spectrometry to investigate changes to immune systems, in particular regulatory T-cells (Tregs), in a large cohort of moderate, severe, and critical Japanese coronavirus disease 2019 (COVID-19) patients and healthy controls.

10 Jan 2022

SARS-CoV-2 viral mutations shown to have a limited effect on T cell immunity

New research suggests that viral mutations have a minimal effect on T cell immunity, which could explain the protection provided by vaccination against severe COVID-19, despite the significant loss of neutralizing antibodies.

10 Jan 2022

Frequency News and Research

Study demonstrates that intra-host SARS-CoV-2 variants with reduced infectivity are developed during infection

Monitoring rodents for SARS-CoV-2 and other coronaviruses, Hong Kong

Study reveals factors responsible for increased risk of aerosol transmission for SARS-CoV-2 Delta and Omicron

Similarities and dissimilarities in immune responses and metabolism in SARS-CoV-2 and HIV-1 infections

Insignificant homology of SARS-CoV-2 spike sequences to myocarditis-associated antigens

Virus-like particles as delivery vehicles for gene-editing

Analysis of COVID vaccine breakthrough infections in highly vaccinated Israel

Investigating the presence of human rRNA in the SARS-CoV-2 genome

Forecasting seasonal SARS-CoV-2 mutations

Lack of evidence cross-reactive adaptive immune response is mechanism underlying COVID vaccine-induced myocarditis

Severity of menopause symptoms linked to a woman's cognitive performance

New method for monitoring circulating SARS-CoV-2 variants and detecting new ones

A common cold may boost the immune system against COVID-19

Decoding imagined language to treat people suffering from aphasia

International study offers a clearer picture of COVID-19's impact on children

Developing a 'fingerprint' test that could diagnose Alzheimer’s early

Study finds T cell response mostly conserved against SARS-CoV-2 Omicron variant following infection or vaccination

Higher olive oil consumption linked with lower risk of cardiovascular disease, cancer mortality

Mapping regulatory T-cell populations in COVID-19 patients

SARS-CoV-2 viral mutations shown to have a limited effect on T cell immunity

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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