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Discovering distinct gut-brain pathways for sugars and fats

Researchers identify independent vagal sensing pathways for fat and sugar detection.

23 Jan 2024

Posterior cortical atrophy predicts Alzheimer's, study finds

A team of international researchers, led by UC San Francisco, has completed the first large-scale study of posterior cortical atrophy, a baffling constellation of visuospatial symptoms that present as the first symptoms of Alzheimer's disease.

22 Jan 2024

NHS Health Check linked to lower disease rates and mortality, study shows

Attending an NHS Health Check appointment - a preventative screening programme offered for free in the UK - is associated with both a decreased risk of dying and a decreased risk of several diseases, including dementia and liver cirrhosis.

22 Jan 2024

Team approach to prostate cancer: PCPs and urologists offer hope with active surveillance

This study considers the perspectives of primary care physicians (PCPs) and urologists on what facilitates and what creates barriers to active surveillance (AS) care for men with low-risk prostate cancer.

22 Jan 2024

Monoclonal antibodies for Alzheimer's offer little benefit, raise safety concerns

Researchers performed a meta-analysis of randomized trial studies that compared the use of amyloid-reducing monoclonal antibodies (MABs) in patients with Alzheimer's dementia at a dose consistent with that used in Phase 3 or FDA approval trials with the use of a placebo.

22 Jan 2024

Early warning sign for myeloma found in bone marrow fat cells

A new research perspective was published in Oncotarget's Volume 15 on January 16, 2024, entitled, "Bone marrow adipocytes provide early sign for progression from MGUS to multiple myeloma."

22 Jan 2024

Socioeconomic conditions can shape the brain's sensitivity to rewarding experiences

MIT neuroscientists have found that the brain's sensitivity to rewarding experiences - a critical factor in motivation and attention - can be shaped by socioeconomic conditions.

22 Jan 2024

Thinning brain tissue predicts dementia up to a decade before symptoms

A ribbon of brain tissue called cortical gray matter grows thinner in people who go on to develop dementia, and this appears to be an accurate biomarker of the disease five to 10 years before symptoms appear, researchers from The University of Texas Health Science Center at San Antonio (also called UT Health San Antonio) reported.

22 Jan 2024

Unveiling hidden TB risk with cutting-edge techniques

A novel approach to studying the progression of tuberculosis (TB) from infection to disease has identified and treated people at increased risk of developing the disease that current methods of testing would not.

22 Jan 2024

Study provides new insights into aging process of the human mind

A team of scientists from Nanyang Technological University, Singapore (NTU Singapore) has demonstrated that communication among memory-coding neurons - nerve cells in the brain responsible for maintaining working memory - is disrupted with aging and that this can begin in middle age.

22 Jan 2024

Innovative diabetes detection method with DiaNet v2, utilizing retinal imaging technology

Innovative diabetes detection method with DiaNet v2, utilizing retinal imaging technology.

22 Jan 2024

Study reveals surprising power of CD4+ T cells against melanoma

In the study led by the Peter Doherty Institute for Infection and Immunity (Doherty Institute) and published in Science Immunology, the researchers found that CD4+ T cells, traditionally called ‘helper T cells’ for their role in aiding the activation of other immune cells, are remarkably effective in controlling melanoma.

22 Jan 2024

HoloCare launches 3D surgical holograms across the UK and Europe

Norwegian healthtech startup HoloCare scales its commercial footprint across the UK and Europe, following UKCA and CE certification.

22 Jan 2024

Ludwig scientists deconstruct the blood supply of brain metastases

A Ludwig Cancer Research study has generated a granular portrait of how the cellular and molecular components of the blood vessels that feed brain metastases of melanoma and lung and breast cancers differ from those of healthy brain tissue, illuminating how they help shape the internal environment of tumors to support cancer growth and immune evasion.

19 Jan 2024

Clinical trial shows MRI and tracking-guided delivery of magnetic stimulation to brains of people with severe depression eases symptoms

Researchers performed a randomized clinical trial to compare resting-state functional magnetic resonance imaging connectivity-guided intermittent theta burst stimulation vs. repetitive transcranial magnetic stimulation for therapy-resistant depression.

19 Jan 2024

Novel imaging approach accurately identifies sub-types of primary aldosteronism

A novel imaging approach, 68Ga-pentixafor PET/CT, has been shown to accurately identify sub-types of primary aldosteronism (an adrenal gland disorder), outperforming traditional methods for diagnosis.

18 Jan 2024

New structural insights pave the way for drug-resistant malaria therapies

Structural insights into a potent antimalarial drug candidate's interaction with the malaria parasite Plasmodium falciparum have paved the way for drug-resistant malaria therapies, according to a new study by researchers at Weill Cornell Medicine and Van Andel Institute.

18 Jan 2024

St. Jude announces $13 million investment to expand the understanding of G-protein coupled receptors

St. Jude Children's Research Hospital today announced a nearly $13 million investment toward a new research collaboration with scientists at Columbia University, Duke University and Stanford University to expand the understanding of G-protein coupled receptors (GPCR), which are vital proteins that impact human health and disease.

18 Jan 2024