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Research could pave the way for therapeutic strategies targeting DCIR to treat colorectal tumors

Colorectal tumors are a common adverse effect of chronic inflammation of the intestine. In a new study, researchers from Japan and China demonstrate that mice models with dendritic cell immunoreceptor (DCIR) protein deficiency are resistant to colonic tumors induced by dextran sodium sulfate and azoxymethane.

2 Aug 2022

ADAR1 mutation sets off biochemical pathways that produce an organ-damaging autoimmune response

A new study shows how mutation of the ADAR1 gene sets off biochemical pathways that produce an autoimmune response that harms the developing brain and other areas of the body.

2 Aug 2022

LJI acquires Carterra LSA instrument to enhance antibody screening and characterization efforts

Carterra, Inc., the world leader in innovative technologies enabling high-throughput biology, and La Jolla Institute for Immunology, a globally recognized non-profit research organization dedicated to understanding the power of the immune system to promote human health, announced today that LJI has acquired a Carterra LSA instrument to enhance its antibody screening and characterization work.

2 Aug 2022

TransCode and MD Anderson scientists collaborate to validate therapeutic and diagnostic candidates

The University of Texas MD Anderson Cancer Center and TransCode Therapeutics, Inc. today announced a strategic alliance to advance TransCode's pipeline of RNA-targeted oncology therapeutic and diagnostic candidates.

2 Aug 2022

Plasma myosin light chain 9 levels may be better predictor of COVID-19 severity than blood biomarkers

In a new study, researchers found elevated plasma levels of myosin light chain 9 (Myl9) in COVID-19 patients with a fatal disease.

2 Aug 2022

Carbon monoxide foam in the fight against inflammation

News-Medical speaks to Leo Otterbein about a novel way to deliver carbon monoxide to the body while bypassing its potentially hazardous effects.

2 Aug 2022

Study: SARS-CoV-2 variants of concern and biological sex of patients affect molnupiravir efficacy

SARS-CoV-2 variants of concern and the biological sex of patients affect the efficacy of molnupiravir, the first orally available drug approved for outpatient use against COVID-19, according to a new study led by researchers in the Center for Translational Antiviral Research in the Institute for Biomedical Sciences at Georgia State University.

1 Aug 2022

Study quantifies link between red meat intake, gut microbiome, and cardiovascular disease in older adults

Does eating more meat - especially red meat and processed meat - raise the risk of cardiovascular disease, and if so, why? Despite intense study, the impact of animal source foods on atherosclerotic cardiovascular disease (ASCVD) is vigorously debated, and the mechanisms underlying potential effects of animal proteins remain unclear.

1 Aug 2022

NIH updates its strategic plan for hepatitis B research

The National Institutes of Health has updated its Strategic Plan for NIH Research to Cure Hepatitis B, a roadmap for ending the hepatitis B epidemic, focused on developing a cure as well as improved strategies for vaccination, screening and follow-up care.

1 Aug 2022

ALZ-NET: First data collection and sharing network for new FDA-approved Alzheimer's treatments

ALZ-NET is the first network developed specifically for new FDA-approved Alzheimer's treatments, collecting real-world evidence on drug effectiveness and side effects over a long period of time.

1 Aug 2022

How and when do de novo SARS-CoV-2 spike mutations emerge?

Researchers evaluated viral mutations in two patients with persistent SARS-CoV-2 infection.

1 Aug 2022

Nutritive intervention could be an effective treatment method in maintaining human health

In a new study, researchers assessed the impact of dietary regulation on human health and disease.

1 Aug 2022

ACROBiosystems was titled 2022 CiteAb Awards protein supplier winner, gaining global scientific approval

Recently, ACROBiosystems won Cite Awards, being titled "the Winner of Protein Supplier to Watch in 2022".

From ACROBiosystems 1 Aug 2022

Decoy ACE2 receptors broadly neutralize SARS-CoV-2 variants

Researchers review current developments in preclinical studies associated with recombinant ACE2 decoy receptors against coronaviruses.

31 Jul 2022

New DNA repair vehicle used to fix a common genetic cause of hereditary kidney disease

Genetic mutations which cause a debilitating hereditary kidney disease affecting children and young adults have been fixed in patient-derived kidney cells using a potentially game-changing DNA repair-kit. The advance developed by University of Bristol scientists is published in Nucleic Acids Research.

29 Jul 2022

Modifi Bio comes up with a new technology to combat cancer cells with DNA modification

Modifi Biosciences announced today that the journal Science has published a critical study validating the company's novel oncology platform based on new classes of molecules that exploit tumor-associated DNA repair defects through direct cancer cell DNA modification.

29 Jul 2022

New glioma drug may represent a paradigm for designing therapeutics exploiting specific DNA repair

A new class of glioma drugs exploits tumors that lack the DNA repair enzyme MGMT; the drugs lead to the generation of cytotoxic DNA and selectively kill tumor cells without the risk of resistance, researchers report.

29 Jul 2022

Study investigates the combined effects of aging and HIV-1 Tat expression in mice

A new research paper was published in Aging ("Aging (Albany NY)" by Medline/PubMed, "Aging-US" by Web of Science) Volume 14, Issue 13, entitled, "Age-related neuroendocrine, cognitive, and behavioral co-morbidities are promoted by HIV-1 Tat expression in male mice."

29 Jul 2022

Predicting viral antibody escape using pre-pandemic data

A new study reports early prediction of SARS-CoV-2 immune evasion using EVEscape.

28 Jul 2022

Study provides a better understanding of accessibility to U.S. drugstores

Almost 90% of the U.S. population lives within 5 miles of a community pharmacy, but more than half of Americans have to commute for more than 1 mile to reach a pharmacist.

28 Jul 2022

Therapeutics News and Research

Research could pave the way for therapeutic strategies targeting DCIR to treat colorectal tumors

ADAR1 mutation sets off biochemical pathways that produce an organ-damaging autoimmune response

LJI acquires Carterra LSA instrument to enhance antibody screening and characterization efforts

TransCode and MD Anderson scientists collaborate to validate therapeutic and diagnostic candidates

Plasma myosin light chain 9 levels may be better predictor of COVID-19 severity than blood biomarkers

Carbon monoxide foam in the fight against inflammation

Study: SARS-CoV-2 variants of concern and biological sex of patients affect molnupiravir efficacy

Study quantifies link between red meat intake, gut microbiome, and cardiovascular disease in older adults

NIH updates its strategic plan for hepatitis B research

ALZ-NET: First data collection and sharing network for new FDA-approved Alzheimer's treatments

How and when do de novo SARS-CoV-2 spike mutations emerge?

Nutritive intervention could be an effective treatment method in maintaining human health

ACROBiosystems was titled 2022 CiteAb Awards protein supplier winner, gaining global scientific approval

Decoy ACE2 receptors broadly neutralize SARS-CoV-2 variants

New DNA repair vehicle used to fix a common genetic cause of hereditary kidney disease

Modifi Bio comes up with a new technology to combat cancer cells with DNA modification

New glioma drug may represent a paradigm for designing therapeutics exploiting specific DNA repair

Study investigates the combined effects of aging and HIV-1 Tat expression in mice

Predicting viral antibody escape using pre-pandemic data

Study provides a better understanding of accessibility to U.S. drugstores

Industry Focus eBook - Cell biology (5th edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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