Gene Expression News and Research

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Gene Expression is the process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.

Major genetic study provides most comprehensive map of breast cancer risk variants to date

A major international study of the genetics of breast cancer has identified more than 350 DNA 'errors' that increase an individual's risk of developing the disease. The scientists involved say these errors may influence as many as 190 genes.

7 Jan 2020

Study uncovers genes controlling mycorrhizal colonization in soybean

Like most plants, soybeans pair up with soil fungi in a symbiotic mycorrhizal relationship. In exchange for a bit of sugar, the fungus acts as an extension of the root system to pull in more phosphorus, nitrogen, micronutrients, and water than the plant could on its own.

6 Jan 2020

Researchers identify key biomarkers for predicting autism in newborns

Because early detection of autism is linked to significantly improved outcomes, the discovery of early predictors could make all the difference in a child's development.

2 Jan 2020

Mount Sinai awarded more than $10 million in federal funding for research on glioblastoma

The Department of Neurosurgery at the Icahn School of Medicine at Mount Sinai has received more than $10 million in federal funding for several projects focusing on brain tumor research.

2 Jan 2020

Advancement in reconstitution of the blood system from human pluripotent stem cells

The reconstitution of the blood system in humans holds great therapeutic potential to treat many disorders, like blood cancers, sickle-cell anemia and others.

31 Dec 2019

Study reveals rapid effects of diet on sperm quality

Sperm are influenced by diet, and the effects arise rapidly. This is the conclusion of a study by researchers at Linköping University, in which healthy young men were fed a diet rich in sugar.

28 Dec 2019

Lab-grown brain organoids may hold the answers to personalized treatments for glioblastomas

Lab-grown brain organoids developed from a patient's own glioblastoma, the most aggressive and common form of brain cancer, may hold the answers on how to best treat it.

26 Dec 2019

CD4 T cells are not to be blamed for pushing dengue fever from bad to worse

No one knows what makes a mild dengue viral infection morph into a severe and sometimes deadly dengue hemorrhagic fever/dengue shock syndrome.

26 Dec 2019

New spatiomolecular map may advance understanding of the brain's decision-making area

Researchers at Karolinska Institutet have come one step closer toward understanding how the part of our brain that is central for decision-making and the development of addiction is organized on a molecular level.

26 Dec 2019

Inserting end-modified DNA fragments with CRISPR-Cas9 yields highest efficiency

University of Illinois researchers achieved the highest reported rates of inserting genes into human cells with the CRISPR-Cas9 gene-editing system, a necessary step for harnessing CRISPR for clinical gene-therapy applications.

23 Dec 2019

NIH awards $1.2 million grant for studying biomolecular interactions to inform better drug design

Biomolecules -- carbohydrates, proteins, nucleic acids, and lipids -- form the foundation of life and are responsible for carrying out every process that occurs in our bodies.

23 Dec 2019

New antibody shows promise in active lupus

A new trial involving the use of an antibody called anifrolumab reports improvement in patients with systemic lupus erythematosus (SLE) after 52 weeks of treatment. The research, titled 'Trial of Anifrolumab in Active Systemic Lupus Erythematosus', is published in the New England Journal of Medicine.

19 Dec 2019

Edematous severe acute malnutrition linked to DNA modification

A group led by researchers at Baylor College of Medicine has identified significant differences at the epigenetic level - the chemical tags in DNA that help regulate gene expression - between two clinically distinct forms of acute childhood malnutrition known as edematous severe acute malnutrition (ESAM) and non-edematous SAM (NESAM).

19 Dec 2019

Glutamine could help obese people reduce inflammation of fat tissue

Glutamine could help people with obesity reduce inflammation of fat tissue and reduce fat mass, according to a new study at Karolinska Institutet in Sweden and the University of Oxford in the U.K. The researchers also show how glutamine levels can alter gene expression in several different cell types.

19 Dec 2019

A new book on ovarian cancer

An opening discussion of contemporary management of this disease presents commentary on surgery and clinical trials: neoadjuvant, dose-dense, and heated intraperitoneal chemotherapy (HIPEC}, as well as immunotherapy, vaccine therapy, emerging therapies.

18 Dec 2019

Study opens up new treatment possibilities for Wilms' tumor

As an embryo develops, its cells must learn what to do with the thousands of genes they've been equipped with. That's why each cell comes with a detailed gene-expression manual outlining exactly which genes should be switched on, to what extent, and when.

18 Dec 2019

Researchers identify frequent technical bias in data generated by RNA-seq technology

Reproducibility of research data is a major challenge in experimental biology. As data generated by genomic-scale techniques increases in complexity, this concern is becoming more and more worrisome.

18 Dec 2019

Scientists develop computationally inspired method for preclinical study of anxiety

Nearly 40 million people in the U.S. have an anxiety disorder. While treatment options exist, treatment success varies, and many people do not respond to treatment until weeks or months after they begin anti-depressants

18 Dec 2019

IU scientists discover that beta-carophyllene improves wound healing

Indiana University researchers have discovered that a chemical compound found in essential oils improves the healing process in mice when it is topically applied to a skin wound -- a finding that could lead to improved treatments for skin injuries in humans.

18 Dec 2019

Moffitt researchers develop efficient method for creating mouse models to study melanoma

Genetically engineered mouse models are often used by scientists to study how the addition, deletion or mutation of genes affects the development of disease and effects of drugs.

17 Dec 2019

Gene Expression News and Research

Further Reading

Major genetic study provides most comprehensive map of breast cancer risk variants to date

Study uncovers genes controlling mycorrhizal colonization in soybean

Researchers identify key biomarkers for predicting autism in newborns

Mount Sinai awarded more than $10 million in federal funding for research on glioblastoma

Advancement in reconstitution of the blood system from human pluripotent stem cells

Study reveals rapid effects of diet on sperm quality

Lab-grown brain organoids may hold the answers to personalized treatments for glioblastomas

CD4 T cells are not to be blamed for pushing dengue fever from bad to worse

New spatiomolecular map may advance understanding of the brain's decision-making area

Inserting end-modified DNA fragments with CRISPR-Cas9 yields highest efficiency

NIH awards $1.2 million grant for studying biomolecular interactions to inform better drug design

New antibody shows promise in active lupus

Edematous severe acute malnutrition linked to DNA modification

Glutamine could help obese people reduce inflammation of fat tissue

A new book on ovarian cancer

Study opens up new treatment possibilities for Wilms' tumor

Researchers identify frequent technical bias in data generated by RNA-seq technology

Scientists develop computationally inspired method for preclinical study of anxiety

IU scientists discover that beta-carophyllene improves wound healing

Moffitt researchers develop efficient method for creating mouse models to study melanoma

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