Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

Specific group of immune cells may influence Alzheimer’s disease

A new study has revealed that the immune system plays a crucial and previously unidentified role in Alzheimer's disease.

9 Jan 2020

Missing one night of sleep may increase Alzheimer's biomarker, study finds

A preliminary study has found that when young, healthy men were deprived of just one night of sleep, they had higher levels of tau, a biomarker for Alzheimer's disease, in their blood than when they had a full, uninterrupted night of rest.

8 Jan 2020

Research project leverages big data to close the gap on cognitive decline and healthy aging

A new research project at the University of Arizona Center for Innovation in Brain Science will apply a big-data approach, using bioinformatics and computational modeling, to better understand the systems biology of Alzheimer's and other neurodegenerative diseases.

8 Jan 2020

A physically and mentally active lifestyle can slow familial frontotemporal dementia

A physically and mentally active lifestyle confers resilience to frontotemporal dementia (FTD), even in people whose genetic profile makes the eventual development of the disease virtually inevitable, according to new research by scientists at the UC San Francisco Memory and Aging Center.

8 Jan 2020

Use of antipsychotic drugs is linked to brain injuries in Alzheimer's patients

Use of antipsychotic medications was associated with an increased risk of head injuries in a study of individuals with Alzheimer's disease. The findings are published in the Journal of the American Geriatrics Society.

8 Jan 2020

Hobbyist DNA services may be vulnerable to genetic hacking

Online services that allow users to upload their genetic information, research genealogy and find lost relatives may be vulnerable to a sort of genetic hacking, according to two geneticists at the University of California, Davis. A paper describing the work is published Jan. 7 in the journal eLife.

7 Jan 2020

NYU Langone Health announces launch of a multidisciplinary Vaccine Center

Building on its illustrious landmark-achieving history in the field of immunology, NYU Langone Health announced today the launch of a Vaccine Center that combines basic research, clinical studies, and public health outreach to prevent the spread of infectious diseases and other immunological disorders.

7 Jan 2020

New clinical study to test retinal screening processes for early detection of Alzheimer's disease

The University of Rhode Island, in collaboration with BayCare Health System in Florida and The Memory and Aging Program at Butler Hospital, an affiliate of The Warren Alpert Medical School of Brown University, is launching a clinical trial of retinal screening processes that could help clinicians detect Alzheimer's disease possibly two or more decades before patients develop life-altering clinical symptoms.

6 Jan 2020

Exercise and a healthy lifestyle shown to reduce the risk of dementia

Research suggests that regular exercise not only improves heart health but can also slow down cognitive decline and potentially delay the onset of dementia.

3 Jan 2020

Study shows dopamine signaling, biological clock connection in overconsumption and obesity

During the years 1976 through 1980, 15% of U.S. adults were obese. Today, about 40% of adults are obese. Another 33% are overweight.

2 Jan 2020

Evidence for engrams as neural basis for memory

Though scientist Richard Semon introduced the concept of the "engram" 115 years ago to posit a neural basis for memory, direct evidence for engrams has only begun to accumulate recently as sophisticated technologies and methods have become available.

2 Jan 2020

Study shows cardiorespiratory exercise is good for the brain's gray matter

Cardiorespiratory exercise -- walking briskly, running, biking and just about any other exercise that gets your heart pumping -- is good for your body, but can it also slow cognitive changes in your brain?

2 Jan 2020

Studying Alzheimer’s and Parkinson’s Disease using Pre-Formed Fibrils

Ariel Louwrier discusses the development of pre-formed tau and alpha-synuclein fibrils for research into Alzheimer's and Parkinson's disease.

From StressMarq Biosciences Inc. 2 Jan 2020

Tau-protein better predicts brain atrophy in Alzheimer's patients than amyloid plaques

Brain imaging of pathological tau-protein "tangles" reliably predicts the location of future brain atrophy in Alzheimer's patients a year or more in advance, according to a new study by scientists at the UC San Francisco Memory and Aging Center. In contrast, the location of amyloid "plaques," which have been the focus of Alzheimer's research and drug development for decades, was found to be of little utility in predicting how damage would unfold as the disease progressed.

2 Jan 2020

Obj-SCD predicts future amyloid accumulation and neurodegeneration

Writing in the December 30, 2019 online issue of Neurology, researchers at University of California San Diego School of Medicine and Veterans Affairs San Diego Healthcare System report that accumulating amyloid -- an abnormal protein linked to neurodegenerative conditions such as Alzheimer's disease -- occurred faster among persons deemed to have "objectively-defined subtle cognitive difficulties" (Obj-SCD) than among persons considered to be "cognitively normal."

31 Dec 2019

New dementia vaccine may proceed to clinical trials after successful testing

A preventive treatment for dementia may proceed to clinical trials after successful animal testing.

31 Dec 2019

Amyloid plaques may not necessarily come first in Alzheimer's disease, suggests new study

The scientific community has long believed that beta-amyloid, a protein that can clump together and form sticky plaques in the brain, is the first sign of Alzheimer's disease. Beta-amyloid then leads to other brain changes including neurodegeneration and eventually to thinking and memory problems. But a new study challenges that theory.

30 Dec 2019

Study measures brain injury from boxing, MMA in younger and older fighters

For boxers and mixed martial arts (MMA) fighters, is there a safe level of exposure to head trauma? A new study shows different effects in the brain for younger, current fighters compared to older, retired fighters.

23 Dec 2019

NIH awards $1.2 million grant for studying biomolecular interactions to inform better drug design

Biomolecules -- carbohydrates, proteins, nucleic acids, and lipids -- form the foundation of life and are responsible for carrying out every process that occurs in our bodies.

23 Dec 2019

McGill study finds new role of apolipoprotein E4 gene in Alzheimer’s disease

For years, physicians have been aware that patients carrying the apolipoprotein E4 (APOEε4) gene are at a greater risk of developing Alzheimer's disease. New research from McGill University has now found the gene plays an even greater role in dementia.

21 Dec 2019

Alzheimer's Disease News and Research

Further Reading

Specific group of immune cells may influence Alzheimer’s disease

Missing one night of sleep may increase Alzheimer's biomarker, study finds

Research project leverages big data to close the gap on cognitive decline and healthy aging

A physically and mentally active lifestyle can slow familial frontotemporal dementia

Use of antipsychotic drugs is linked to brain injuries in Alzheimer's patients

Hobbyist DNA services may be vulnerable to genetic hacking

NYU Langone Health announces launch of a multidisciplinary Vaccine Center

New clinical study to test retinal screening processes for early detection of Alzheimer's disease

Exercise and a healthy lifestyle shown to reduce the risk of dementia

Study shows dopamine signaling, biological clock connection in overconsumption and obesity

Evidence for engrams as neural basis for memory

Study shows cardiorespiratory exercise is good for the brain's gray matter

Studying Alzheimer’s and Parkinson’s Disease using Pre-Formed Fibrils

Tau-protein better predicts brain atrophy in Alzheimer's patients than amyloid plaques

Obj-SCD predicts future amyloid accumulation and neurodegeneration

New dementia vaccine may proceed to clinical trials after successful testing

Amyloid plaques may not necessarily come first in Alzheimer's disease, suggests new study

Study measures brain injury from boxing, MMA in younger and older fighters

NIH awards $1.2 million grant for studying biomolecular interactions to inform better drug design

McGill study finds new role of apolipoprotein E4 gene in Alzheimer’s disease

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