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Study offers insight into molecular biology of the brain in bipolar disorder patients

In a comprehensive study involving one of the largest-ever samples of post-mortem brains, scientists at the Lieber Institute for Brain Development, in collaboration with researchers at the Johns Hopkins School of Medicine and Bloomberg School of Public Health, have pinpointed significant differences in gene expression in two specific regions of the brains of hundreds of patients who had bipolar disorder.

7 Mar 2022

Some blood cells remain in tissues for years, research finds

Human immune cells not only circulate in the blood, but can also occupy certain tissues and sometimes remain there for years.

7 Mar 2022

Slowing down the DNA replication speed increases cell reprogramming efficiency

Adult cells in our body can only give rise to the same cell type. For example, a skin cell cannot give rise to a muscle cell but to skin cells only.

7 Mar 2022

NETosis in COVID-19 and MIS-C

A new study investigates the role played by neutrophil extracellular traps formation and degradation in COVID-19.

7 Mar 2022

Study explores COVID-19 vaccine effectiveness in ankylosing spondylitis patients

Researchers estimated the immunogenicity of SARS-CoV-2 vaccination in a Belgian cohort of patients with ankylosing spondylitis.

7 Mar 2022

A special surgical microscope to illuminate blood, bacterial biofilms, cartilage, and soft tissue

Inflammation of the middle ear is often triggered a cholesteatoma, an aggressive form of chronic otitis media. In order to detect cholesteatomas and bacterial biofilms and to remove them safely, the new collaborative project 'BetterView' is working on a special surgical microscope.

4 Mar 2022

Melanoma patients do better on immunotherapy than completion lymph node dissection

For years, surgery for patients with stage III melanoma - melanoma that has spread to the lymph nodes - involved removing those lymph nodes along with the primary tumor.

4 Mar 2022

New policy brief outlines recommendations for testing methods to detect endocrine disruptors

A new policy brief outlines recommendations for tests to identify endocrine disruptors (EDs). The brief has been published by EURION, a cluster of projects working on emerging ED research.

4 Mar 2022

Microneedle treatments could significantly desensitize people with food allergies

Treating peanut allergy with microneedles could significantly improve desensitization by directly targeting the allergen to the skin, providing greater protection from severe allergic reactions for millions of people, a new study suggests.

4 Mar 2022

Microsurgical replantation should be expanded beyond current clinical practice, experts say

The composite tissue transfer techniques used and refined in face transplant surgery may also be used to perform microsurgical replantation – using the person's own tissues – in patients with other types of severe facial injuries, suggests a clinical report in The Journal of Craniofacial Surgery.

4 Mar 2022

See it to Believe it: How Medical Imaging Technologies Could Help Reduce Health Risks and Inspire Behavior Change

In this interview, we speak to Dr Gareth Hollands about his latest research that investigated the use of medical imaging to reduce health risks and encourage behavior change.

4 Mar 2022

Visualizing health risks with medical imaging may discourage risk-related behaviors, finds study

They say a picture can convey a thousand words, and researchers have found that using medical imaging technologies that can visualize health may discourage risk-related behaviors more than non-visual information.

4 Mar 2022

Targeting necroptosis using a necroptosis inhibitor lessens myositis-induced muscle weakness

A new study has suggested that treatment to target necroptosis in muscle fibers using a necroptosis inhibitor lessens myositis-induced muscle weakness as well as muscle cell death and inflammation in the muscles. This has been shown to be a promising strategy for treating polymyositis.

2 Mar 2022

Penn Medicine receives $12.3 million NIH grant to study FLASH radiotherapy for cancer

With more than $12 million in new funding from the National Institutes of Health, the Abramson Cancer Center at the University of Pennsylvania will build on its preclinical research of an emerging form of radiation that provides ultra-fast doses - of under a second, compared to several minutes with conventional radiation - and shows promise of greater protection of normal tissue, thereby minimizing toxic effects to the body.

1 Mar 2022

Microorganisms hindering cancer therapy have more influence than the beneficial ones, study says

Melanoma patients receiving therapy that helps their immune system kill cancer cells respond to treatment differently depending on the types of microbes in their gut, and new research suggests the microorganisms hindering therapy have more influence than the beneficial ones.

28 Feb 2022

Researchers show a relationship between regionalized myocardial fibrosis and mitral valve prolapse

The larger the sail, the more wind it catches. But as that size increases, so does the stress experienced by each sheet and line connected to the canvas.

28 Feb 2022

Novel molecular pathway shared by two neurodegenerative disorders discovered

Scientists from two independent research teams have discovered how the mislocalization of a protein, known as TDP-43, alters the genetic instructions for UNC13A, providing a possible therapeutic target that could also have implications in treating amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), and other forms of dementia.

28 Feb 2022

Mechanism behind how certain osmolytes cause kidney damage revealed

Researchers from Tokyo Metropolitan University have uncovered the mechanism by which osmolytes used to treat high fluid pressure in the eye and skull can cause kidney damage.

27 Feb 2022

Treatment with Tumor Treating Fields triggers downstream anti-tumor cell response, study finds

Novocure announced that a new study published in the Journal of Clinical Investigation (JCI) finds treatment with Tumor Treating Fields (TTFields) mediated cell disruption activates the immune system and triggers an anti-tumor cell response that may be effectively used together with existing immunotherapy approaches in the treatment of solid tumors, with limited systemic toxicity.

25 Feb 2022

Interleukin-1 Receptor-Like 2 cytokine accomplishes a dual effect in inflammation and healing

The Interleukin-1 Receptor-Like 2 (IL-1RL2) cytokine can promote inflammatory diseases and have a role in controlling infection.

24 Feb 2022

Skin News and Research

Study offers insight into molecular biology of the brain in bipolar disorder patients

Some blood cells remain in tissues for years, research finds

Slowing down the DNA replication speed increases cell reprogramming efficiency

NETosis in COVID-19 and MIS-C

Study explores COVID-19 vaccine effectiveness in ankylosing spondylitis patients

A special surgical microscope to illuminate blood, bacterial biofilms, cartilage, and soft tissue

Melanoma patients do better on immunotherapy than completion lymph node dissection

New policy brief outlines recommendations for testing methods to detect endocrine disruptors

Microneedle treatments could significantly desensitize people with food allergies

Microsurgical replantation should be expanded beyond current clinical practice, experts say

See it to Believe it: How Medical Imaging Technologies Could Help Reduce Health Risks and Inspire Behavior Change

Visualizing health risks with medical imaging may discourage risk-related behaviors, finds study

Targeting necroptosis using a necroptosis inhibitor lessens myositis-induced muscle weakness

Penn Medicine receives $12.3 million NIH grant to study FLASH radiotherapy for cancer

Microorganisms hindering cancer therapy have more influence than the beneficial ones, study says

Researchers show a relationship between regionalized myocardial fibrosis and mitral valve prolapse

Novel molecular pathway shared by two neurodegenerative disorders discovered

Mechanism behind how certain osmolytes cause kidney damage revealed

Treatment with Tumor Treating Fields triggers downstream anti-tumor cell response, study finds

Interleukin-1 Receptor-Like 2 cytokine accomplishes a dual effect in inflammation and healing

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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