Therapeutics News and Research

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SARS-CoV-2 3CLpro also susceptible to mutations

Researchers assess the activity of all potential mutations in the SARS-CoV-2 3CLpro.

29 Jun 2022

Scientists report autoimmunity from molecular mimicry between SARS-CoV-2 spike and human proteins

A new study focused on studying molecular mimicry between the S protein of SARS-CoV-2 and known epitopes, using a computational method.

29 Jun 2022

Immune particles from llama blood could offer protection against several COVID-19 variants

Mount Sinai-led researchers have shown that tiny, robust immune particles derived from the blood of a llama could provide strong protection against every COVID-19 variant, including Omicron, and 18 similar viruses including SARS-CoV-2 and SARS-CoV-1, which was responsible for the 2003 SARS outbreak.

29 Jun 2022

Investigating the prerequisites for developing RNA-based antibiotics

In the fight against the Covid-19 pandemic, mRNA-based vaccines have impressively demonstrated their potential. Using this technology, scientists were able to rapidly develop and bring to market vaccines against SARS-CoV-2 that have been extremely effective at protecting millions of people against severe disease progression of COVID-19 or even death.

29 Jun 2022

New study looks at the role of beta cells in triggering autoimmunity

Research into the causes of type 1 diabetes often focuses on the autoimmune response, where the immune system destroys pancreatic islet beta cells that produce insulin.

28 Jun 2022

Scientists discover how to prevent T cell exhaustion to maintain the fight against cancer

When faced with a formidable foe for months on end, the immune system's T cells begin to tire. Whether fighting a cancer or a chronic infection, they become less effective over time, a phenomenon dubbed "T cell exhaustion" by scientists.

28 Jun 2022

Cell-based assay highlights differences in antibody neutralizing capacity for SARS-CoV-2 variants

A recent study by scientists at Celentyx Ltd, the University of Birmingham, and the University of Warwick and posted to the bioRxiv* preprint server illustrated a cell-based severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein attachment assay.

28 Jun 2022

Researchers analyze potential of niclosamide as a SARS-CoV-2 treatment

A recent study posted to the bioRxiv* preprint server assessed whether niclosamide could be employed in coronavirus disease 2019 (COVID-19) therapy.

28 Jun 2022

Study reveals surprising reasons why cancer cells are often forced to rely on fat imports

Columbia and MIT researchers are revealing the surprising reasons why cancer cells are often forced to rely on fat imports, a finding that could lead to new ways to understand and slow down tumor growth.

27 Jun 2022

Studies discover multiple gene variants that contribute to the risk and severity of NAFLD in children

In a pair of overlapping studies, a diverse team of researchers, led by scientists at University of California San Diego School of Medicine, have deepened investigations into the genetic origins of nonalcoholic fatty liver disease (NAFLD) in children, describing multiple gene variants (including some previously unknown) that contribute to the risk of developing NAFLD and gene variants associated with the severity of the liver disease.

27 Jun 2022

Study discovers microbial link between Western-style diet and colorectal cancer risk

New research builds the case that a Western-style diet - rich in red and processed meat, sugar and refined grains/carbohydrates - is tied to higher risk of colorectal cancer through the intestinal microbiota. Investigators from Brigham and Women's Hospital with collaborators looked at data from more than 134,000 participants from two U.S.-wide prospective cohort studies.

27 Jun 2022

LUCID: music, medicine, and machine learning

In this interview, News-Medical speaks to Zoë Thomson, Co-founder and Chief Innovation Officer of LUCID, about how music and machine learning are changing how we approach mental and neuropsychiatric health.

27 Jun 2022

Biodegradable nanomaterials can take images and deliver medicine to combat peripheral arterial disease

A University of Texas at Arlington bioengineer is leading a project that will develop biodegradable nanomaterials that will take pictures and deliver medicine to combat peripheral arterial disease (PAD).

24 Jun 2022

Researchers identify orally efficacious antiviral drug against respiratory syncytial virus

An oral antiviral drug that targets a key part of the respiratory syncytial virus (RSV) polymerase and inhibits the synthesis of viral genetic material has been identified, a finding that could provide an effective treatment against RSV disease, according to researchers in the Center for Translational Antiviral Research at Georgia State University.

24 Jun 2022

Study uncovers cryptic vulnerabilities in RET oncogene that could aid in anti-cancer drug design

RET is a receptor protein with tyrosine kinase activity that can transfer a phosphate group from ATP to other molecules modifying their shape and function in signaling pathways that are essential to organogenesis and tissue maintenance.

24 Jun 2022

MD Anderson announces collaborative alliance with Turning Point Therapeutics to advance new treatment options for cancer patients

The University of Texas MD Anderson Cancer Center and Turning Point Therapeutics, Inc., today announced a strategic research and development alliance to expand the evaluation of two of Turning Point's investigational small molecules focusing on precision medicine targets well known in oncology.

24 Jun 2022

Therapeutics News and Research

SARS-CoV-2 3CLpro also susceptible to mutations

Scientists report autoimmunity from molecular mimicry between SARS-CoV-2 spike and human proteins

Immune particles from llama blood could offer protection against several COVID-19 variants

Investigating the prerequisites for developing RNA-based antibiotics

New study looks at the role of beta cells in triggering autoimmunity

Scientists discover how to prevent T cell exhaustion to maintain the fight against cancer

Cell-based assay highlights differences in antibody neutralizing capacity for SARS-CoV-2 variants

Researchers analyze potential of niclosamide as a SARS-CoV-2 treatment

Study reveals surprising reasons why cancer cells are often forced to rely on fat imports

Studies discover multiple gene variants that contribute to the risk and severity of NAFLD in children

Study discovers microbial link between Western-style diet and colorectal cancer risk

LUCID: music, medicine, and machine learning

Biodegradable nanomaterials can take images and deliver medicine to combat peripheral arterial disease

Researchers identify orally efficacious antiviral drug against respiratory syncytial virus

Study uncovers cryptic vulnerabilities in RET oncogene that could aid in anti-cancer drug design

MD Anderson announces collaborative alliance with Turning Point Therapeutics to advance new treatment options for cancer patients

New nanoparticles effectively stopped the growth and spread of ovarian, liver tumors in mice

U-M researchers reveal how a mutated protein acts as risk factor in Parkinson’s disease

Researchers discover two important novel aspects of APOE4 gene in Alzheimer's patients

Scientists reveal mutational frequency in SARS-CoV-2 proteome based on structural characteristics

Event guide: The Non-Opioid Pain Therapeutics Summit eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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