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‘Cell line atlas’ can help better understand biliary tract cancer biology

Advanced biliary tract cancer (BTC) includes cholangiocarcinoma, gallbladder carcinoma, and ampullary carcinoma. BTC is a rare and aggressive group of cancers, carrying one of the worst prognoses in all of oncology.

12 May 2025

Exploring the role of RNA binding proteins and circular RNAs in cancer

The interaction between RNA-binding proteins (RBPs) and circular RNAs (circRNAs) has emerged as a key area of interest in understanding cancer biology.

12 May 2025

Exploring how play affects cognitive functioning in children with autism

Step into physical therapy professor Anjana Bhat's colorful Move 2 Learn Innovation Lab on the University of Delaware's Science, Technology and Advanced Research (STAR) Campus, and you may see children moving to the beat or leaping over structures as part of an obstacle course.

12 May 2025

Testosterone use not linked to increased gynecological cancer risk in early years

Transmasculine and gender-diverse individuals who use testosterone are not at increased risk of gynecological cancer in the first years of hormone therapy.

12 May 2025

HER3 reemerges as a key driver of cancer progression and therapy resistance

A new publication shines a spotlight on HER3, a long-overlooked member of the ErbB receptor family, revealing its critical role in cancer progression and resistance to therapy.

12 May 2025

CAR-T cell therapy linked to brain fog in cancer patients

After treatment with CAR-T cells - immune cells engineered to attack cancer - patients sometimes tell their doctors they feel like they have "brain fog," or forgetfulness and difficulty concentrating.

12 May 2025

Blood-based biomarkers predict therapy failure in prostate cancer patients

New research has identified specific blood-based biomarkers that can predict the failure of prostate cancer treatment in both hormone-sensitive and castration-resistant patients.

12 May 2025

Tirzepatide outperforms semaglutide for weight loss in people without diabetes

A head-to-head trial found that tirzepatide led to significantly greater weight loss and waist reduction than semaglutide in adults with obesity but without diabetes. Over 72 weeks, tirzepatide helped more participants reach key weight loss milestones, with manageable side effects and strong metabolic benefits.

12 May 2025

Novel Alzheimer's therapy shows low risk of severe side effects

The Food and Drug Administration's approval in 2023 of lecanemab - a novel Alzheimer's therapy shown in clinical trials to modestly slow disease progression - was met with enthusiasm by many in the field as it represented the first medication of its kind able to influence the disease.

12 May 2025

WHO Results Report 2024 shows progress on global health goals amid financial uncertainties

The World Health Organization (WHO) Results Report 2024, shows progress on global health goals, even in times of growing financial uncertainties.

12 May 2025

Research sheds light on the profound connections between diet, inflammation, and gum health

New research presented at EuroPerio11 sheds light on the profound connections between diet, inflammation, and gum health.

12 May 2025

Probiotics show promise in supporting breast cancer patients during chemotherapy

Chemotherapy is one of the most popular ways to treat breast cancer. Even though it has proven to be effective, it also has downsides, such as a higher risk of side effects, as it doesn't only attack the cancer cells but can also affect normal cells.

12 May 2025

Medicaid payments barely keep hospital mental health units afloat. Federal cuts could sink them.

This town's hospital is a holdout on behalf of people going through mental health crises. The facility's leaders have pledged not to shutter their inpatient psychiatric unit, as dozens of other U.S. hospitals have.

12 May 2025

Long term steroid use raises risk of adrenal insufficiency

Individuals taking steroid tablets for more than 3 months are over 6 times more likely to be diagnosed with adrenal insufficiency than those treated with non-steroidal anti-inflammatory drugs, according to research presented at the first Joint Congress between the European Society of Paediatric Endocrinology (ESPE) and the European Society of Endocrinology (ESE).

11 May 2025

Early menopause increases risk of fatty liver disease and metabolic disorders

Women who experience menopause before the age of 50 - and especially before the age of 45 - are more likely to develop fatty liver disease and its related metabolic risk factors within one year after menopause, according to research presented at the first Joint Congress between the European Society of Paediatric Endocrinology (ESPE) and the European Society of Endocrinology (ESE).

11 May 2025

Trump team faces key legal decision that could put mental health parity in peril

The Trump administration must soon make a decision that will affect millions of Americans' ability to access and afford mental health and addiction care.

9 May 2025

Precision nano therapy targets tumor nerves in pancreatic cancer

Announcing a new publication for Acta Materia Medica journal. A preclinical study has developed a precision nano-intervention strategy targeting tumor-associated nerves to destroy nerve-fueled tumor growth in pancreatic cancer.

8 May 2025

St. Jude Children's scientists use brain organoids to study rare encephalopathy

While extremely rare, encephalopathy (a condition affecting brain function) triggered by mutations in the UBA5 gene has devastating impacts, with affected individuals reaching few developmental milestones and experiencing frequent and early-onset seizures.

8 May 2025

AI tool uses facial images to predict biological age and cancer survival

Eyes may be the window to the soul, but a person's biological age could be reflected in their facial characteristics. Investigators from Mass General Brigham developed a deep learning algorithm called FaceAge that uses a photo of a person's face to predict biological age and survival outcomes for patients with cancer.

8 May 2025

Long-acting HIV drug emerges from decades of research and advocacy

In the hunt for a remedy, when the baton is passed from dedicated academic scientists to an innovative company to trusted community advocates, outcomes for society can be especially powerful.

8 May 2025