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New anti-Wolbachia drug could potentially treat onchocerciasis and lymphatic filariasis

Researchers from LSTM and the University of Liverpool have successfully optimized a hit from a whole cell screening of a 10000-compound library to deliver the first novel fully synthetic and rationally designed anti-Wolbachia drug, AWZ1066S, which could potentially be used to treat onchocerciasis and lymphatic filariasis.

8 Jan 2019

The Opal: Pushing the Boundaries of Parkinson’s Disease Research

An interview with Dr. Kristen Sowalsky, discussing a wearable gait sensor and its impact on Parkinson’s disease research.

From APDM Wearable Technologies 8 Jan 2019

MGH-led research team reveals how solid stress impacts tissue surrounding brain tumors

A Massachusetts General Hospital-led research team has demonstrated, for the first time, how solid stress - the physical forces exerted by the solid components of a tumor - impacts the tissue surrounding brain tumors and contributes to resulting neurological dysfunction and neuronal cell death.

8 Jan 2019

Cardiac events, stroke result in unemployment, lower income among survivors of working age

People who have experienced a heart attack (myocardial infarction), stroke or cardiac arrest are significantly less likely to be working than healthy people, and if they are working, on average have lower incomes, found a study published in CMAJ.

7 Jan 2019

Study suggests single-person gowning step to help optimize sterile technique in the OR

For surgeons getting ready to enter the operating room, the chances of contamination may be lower if they put their gowns on by themselves - without the assistance of a surgical technician, according to an experimental study in the Journal of Orthopaedic Trauma. The journal is published in the Lippincott portfolio by Wolters Kluwer.

7 Jan 2019

FORTE study offers new and revealing window into outcomes of trauma patients

Trauma is a leading cause of disability in the world, resulting in more disability-adjusted life years than any other disease. While in-hospital, trauma-related mortality has decreased to just 4 percent in the U.S., little is known about what happens to the 96 percent of patients who survive their trauma injuries but may suffer debilitating long-term effects.

4 Jan 2019

Advances in artificial intelligence threaten privacy of people's health data

Advances in artificial intelligence have created new threats to the privacy of people's health data, a new University of California, Berkeley, study shows.

4 Jan 2019

Risk of depression, anxiety found to be higher among adults with cerebral palsy

Adults with cerebral palsy have a higher risk of developing depression and anxiety than their peers without the condition, a new study in the journal JAMA Neurology reports.

2 Jan 2019

New editorial proposes changes to improve minority representation in clinical trials

In an editorial published in CNS Spectrums, Jay Avasarala, MD, PhD, takes the research community to task for its lack of minority representation in Phase III clinical trials for drugs to treat Multiple Sclerosis (MS).

2 Jan 2019

Researchers report uncertainty around long-term effectiveness of medications to control knee osteoarthritis pain

Managing osteoarthritis requires long-term treatment for symptoms such as pain and changes in joint structure that can lead to disability.

24 Dec 2018

Researchers develop artificial intelligence system to diagnose, classify brain hemorrhages

A team of investigators from the Massachusetts General Hospital Department of Radiology has developed a system using artificial intelligence to quickly diagnose and classify brain hemorrhages and to provide the basis of its decisions from relatively small image datasets.

21 Dec 2018

When needs arise, these older women have one another’s backs

Like many women aging alone, Eileen Kobrin worried that an accident could compromise her independence.

20 Dec 2018

Choking deaths pose serious threat to the wellbeing of people with disability

Speech Pathology Australia welcomes the Victorian Disability Services Commissioner’s report, “A review of disability service provision to people who have died 2017-18”, tabled in the Victorian Parliament yesterday, 19 December.

20 Dec 2018

Review highlights calcium handling mechanisms involved in reperfusion injury

Stroke and myocardial infarction (MI) are a significant cause of death and disability worldwide. However, over the past several decades because of advances in medicines (thrombolytic agents, antiplatelet drugs, beta blockers, and angiotensin converting enzyme inhibitors) and approaches to restore tissue perfusion (percutaneous coronary intervention and cardiopulmonary bypass), the mortality of MI has declined dramatically.

20 Dec 2018

European scientists aim to identify causes of dementia

Dementia is common to a variety of neurodegenerative diseases such as Alzheimer's disease, Parkinson disease and Down syndrome. This common symptom is one of the major causes of disability and dependency among older people.

19 Dec 2018

Universal meningitis vaccination for college students may be too costly, study suggests

A computer-generated model developed by Johns Hopkins Medicine researchers adds to evidence that providing universal vaccination against meningitis B infection to students entering college may be too costly to justify the absolute number of cases it would prevent.

19 Dec 2018

Researchers uncover genes that play a key role in the inactivation of X chromosomes

In cell biology, men and women are unequal: men have an X chromosome, while women have two. How can we get around this difference?

19 Dec 2018

Meningococcal bacteria with antibiotic resistance are at risk of increasing worldwide

In a new report published in Expert Review of Vaccines, the Global Meningococcal Initiative- a leading group of scientists, doctors and public health officials - warns that the incidence of meningococcal meningitis strains with resistance to traditional antibiotics is at risk of increasing worldwide.

19 Dec 2018

Study: Dancing could help older women to perform their daily tasks

A new study published in the Scandinavian Journal of Medicine and Science in Sports examined the potential effects of 16 different exercise types for reducing disability for activities of daily living (ADL) in older women.

19 Dec 2018

New study reveals best assessment tools to establish delirium severity

A study published today in JAMA Internal Medicine reveals the best assessment tools available to establish the severity of diagnosed delirium in hospitalized patients. Delirium is a common, serious, and often preventable complication among older adult patients.

17 Dec 2018

Disability News and Research

New anti-Wolbachia drug could potentially treat onchocerciasis and lymphatic filariasis

The Opal: Pushing the Boundaries of Parkinson’s Disease Research

MGH-led research team reveals how solid stress impacts tissue surrounding brain tumors

Cardiac events, stroke result in unemployment, lower income among survivors of working age

Study suggests single-person gowning step to help optimize sterile technique in the OR

FORTE study offers new and revealing window into outcomes of trauma patients

Advances in artificial intelligence threaten privacy of people's health data

Risk of depression, anxiety found to be higher among adults with cerebral palsy

New editorial proposes changes to improve minority representation in clinical trials

Researchers report uncertainty around long-term effectiveness of medications to control knee osteoarthritis pain

Researchers develop artificial intelligence system to diagnose, classify brain hemorrhages

When needs arise, these older women have one another’s backs

Choking deaths pose serious threat to the wellbeing of people with disability

Review highlights calcium handling mechanisms involved in reperfusion injury

European scientists aim to identify causes of dementia

Universal meningitis vaccination for college students may be too costly, study suggests

Researchers uncover genes that play a key role in the inactivation of X chromosomes

Meningococcal bacteria with antibiotic resistance are at risk of increasing worldwide

Study: Dancing could help older women to perform their daily tasks

New study reveals best assessment tools to establish delirium severity

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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