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Study pinpoints electrophysiological mechanism behind upper motor neuron disease

Scientists from Northwestern Medicine and the University of Belgrade have pinpointed the electrophysiological mechanism behind upper motor neuron disease, unlocking the door to potential treatments for amyotrophic lateral sclerosis and other neurodegenerative diseases, such as Hereditary Spastic Paraplegia and Primary Lateral Sclerosis.

21 May 2020

Paper-based device measures lithium ion concentration in blood of bipolar disorder patients

A group of Hokkaido University researchers has developed a paper-based device that can easily and cheaply measure lithium ion concentration in blood, which could greatly help bipolar disorder patients.

21 May 2020

Magnetic core-shell iron nanowires can be used for noninvasive medical imaging

Living cells inside the body could be placed under surveillance--their location and migration noninvasively tracked in real time over many days--using a new method developed by researchers at KAUST.

20 May 2020

New technique reveals potentially treatable mutations in subset of prostate cancer patients

Prostate cancer patients who do not respond well to PSMA-targeted therapy often have potentially treatable mutations in their DNA damage-repair genes, according to research published in the May issue of The Journal of Nuclear Medicine.

20 May 2020

Researchers highlight the need to revise the protocol for detecting ZIKV infection in placenta

Shortly after the explosion in microcephaly cases caused by Zika virus in Brazil in 2015-16, several scientific studies were published with evidence that the pathogen is capable of crossing the human placenta, the organ that keeps the fetus connected to the mother's body during pregnancy.

20 May 2020

Immunotherapy, steroids restore heart function in children with COVID-related multi-system inflammatory syndrome

Treatment with antibodies purified from donated blood - immune globulin therapy - and steroids restored heart function in the majority of children with COVID-related multi-system inflammatory syndrome, according to new research published yesterday in Circulation, the flagship journal of the American Heart Association.

19 May 2020

Steroids and immunotherapy improve outcomes in children with COVID-related multi-system inflammatory syndrome

19 May 2020

Study shows how normal RAS interacts with mutated RAS in living cells

Many cancer medications fail to effectively target the most commonly mutated cancer genes in humans, called RAS.

19 May 2020

ECMO machine can be useful for treating critically ill COVID-19 patients

When COVID-19 patients are critically ill, the biggest threat to their lives is lung dysfunction. If their lungs don't work, their blood can't circulate enough oxygen to the brain, the liver and other organs.

18 May 2020

Common mutations in SARS-CoV-2 related to non-variable segments of structural proteins

The ongoing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic is thought to have originated from an animal species, most likely bats, which succeeded in crossing over to humans. However, the exact species of origin has not yet been confirmed.

18 May 2020

Potential new treatment approach to fatal COVID-19

Researchers from the University of Colorado Anschutz Medical Campus and Pathways Bioscience in the United States have found that activating a transcription factor involved in oxidative stress regulation, antiviral activity, and inflammation may serve as a new treatment approach to coronavirus disease 2019 (COVID-19).

18 May 2020

Novel insights on SARS-CoV-2 cell entry may inform further vaccine and treatment development

A research group from Harvard Medical School reported two cryo-electron microscopy structures derived from a single preparation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein in their paper available on the preprint server bioRxiv. Understanding the nuances of prefusion and postfusion conformations shed light on viral cell entry and may, in turn, guide the development of vaccines and drugs.

18 May 2020

Researchers develop potential drug compound for treating cancer

Researchers at the University of Eastern Finland have developed a new and promising drug compound for the treatment of cancer that inhibits natural amino acids from entering cancer cells.

18 May 2020

New and unexplored angle in the binding of SARS-CoV-2 to host cells

Researchers in the Netherlands, Cuba, and Italy have made important discoveries about the carbohydrate-mediated binding of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein to host cell lectin receptors and host lung microbiota.

17 May 2020

Researchers develop new method to study the effect of long-term oxygen deficiency

Researchers at Luleå University of Technology have developed a method to study how muscle cells in the blood vessels of the lung, permanently contract because of long-term oxygen deficiency.

15 May 2020

Using supercomputers to screen drugs for deadly heart arrhythmias

Death from sudden cardiac arrest makes headlines when it strikes athletes. But it also causes the most deaths by natural causes in the U.S. estimated at 325,000 per year.

14 May 2020

Visual Science designs a scientific model of SARS-Cov-2 virus

The biomedical visualization studio Visual Science has created the most detailed and scientifically accurate 3D model of the full SARS-CoV-2 virus at atomic resolution.

14 May 2020

Scientists describe new mechanism of cellular locomotion

Whilst the whole world is in lockdown during the current Corona crisis, certain cells within our bodies are still travelling long-distance: while this happens when you develop pneumonia, any ordinary cut on your finger will also trigger white blood cells--aka leukocytes--to instantly move out of your blood vessels into the site of inflammation.

14 May 2020

Study uncovers how the body synthesizes triglycerides

Doctors regularly warn their patients that having high levels of triglycerides, a major dietary fat, can increase the risk of heart disease, diabetes, obesity and fatty liver disease.

13 May 2020

Research identifies a disease trigger for pancreatitis

One factor contributing to the development of pancreatitis lies in mutations within a cell membrane ion channel that is characterized by its specific permeability for calcium ions.

13 May 2020

Membrane News and Research

Study pinpoints electrophysiological mechanism behind upper motor neuron disease

Paper-based device measures lithium ion concentration in blood of bipolar disorder patients

Magnetic core-shell iron nanowires can be used for noninvasive medical imaging

New technique reveals potentially treatable mutations in subset of prostate cancer patients

Researchers highlight the need to revise the protocol for detecting ZIKV infection in placenta

Immunotherapy, steroids restore heart function in children with COVID-related multi-system inflammatory syndrome

Steroids and immunotherapy improve outcomes in children with COVID-related multi-system inflammatory syndrome

Study shows how normal RAS interacts with mutated RAS in living cells

ECMO machine can be useful for treating critically ill COVID-19 patients

Common mutations in SARS-CoV-2 related to non-variable segments of structural proteins

Potential new treatment approach to fatal COVID-19

Novel insights on SARS-CoV-2 cell entry may inform further vaccine and treatment development

Researchers develop potential drug compound for treating cancer

New and unexplored angle in the binding of SARS-CoV-2 to host cells

Researchers develop new method to study the effect of long-term oxygen deficiency

Using supercomputers to screen drugs for deadly heart arrhythmias

Visual Science designs a scientific model of SARS-Cov-2 virus

Scientists describe new mechanism of cellular locomotion

Study uncovers how the body synthesizes triglycerides

Research identifies a disease trigger for pancreatitis

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