Mutation News and Research

RSS

New combination therapy may help fight antimicrobial resistance

An inexpensive, FDA-approved drug -- cholestyramine -- taken in conjunction with an antibiotic prevents the antibiotic from driving antimicrobial resistance, according to new research by scientists at Penn State and the University of Michigan. The team's findings appear today (Dec. 1) in the journal eLife.

2 Dec 2020

Research suggests plant flavonols could serve as effective antivirals for SARS-CoV-2

Researchers in Algeria have reviewed some of the evidence suggesting that flavonols commonly found in many plants and vegetables could be used as a therapeutic approach to coronavirus disease 2019 (COVID-19).

1 Dec 2020

Study uncovers a promising therapeutic target for retinal dystrophies

A team of LSU Health New Orleans researchers reports for the first time that deleting one of the inhibitors of the RPE65 gene in a mouse model that carries a human disease mutation prevents degeneration of cone photoreceptors that are used for daytime high-resolution color vision.

1 Dec 2020

Experimental stem cell gene therapy may give a new lease of life for patient with sickle cell disease

"But it's a marathon whereas you keep going, the trail gets rockier and then you lose your shoes," the 27-year-old said. "It gets harder as you get older. Things start to fail and all you can think about is how much worse it's going to get down the road."

1 Dec 2020

Clonal hematopoiesis linked to severe COVID-19

Now, an international team of researchers from the USA, South Korea and Canada has found that clonal hematopoiesis is tied to the risk of severe COVID-19.

30 Nov 2020

A mutant SARS-CoV-2 subspecies from minks may evade antibody detection

In a recent research letter published on the bioRxiv preprint server, scientists from Japan discovered that the mutation of spike glycoprotein in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) derived from farmed minks can also be found in the group of individuals with coronavirus disease (COVID-19) and subsequently evade detection by our immune system.

30 Nov 2020

Adding exercise to genetic treatment reverses fatigue in mice with common myotonic dystrophy

Adding exercise to a genetic treatment for myotonic dystrophy type 1 (DM1) was more effective at reversing fatigue than administering the treatment alone in a study using a mouse model of the disease.

30 Nov 2020

SARS-CoV-2 spike protein shows slow but stable evolution, study finds

A new preprint published in November 2020 describes the seven different clades into which the virus has diversified.

27 Nov 2020

N439K mutation of SARS-CoV-2 may be more infectious and antibody resistant than Wuhan strain

Researchers from the Harbin Institute of Technology, China, modeled the complexes formed between the RBD and the human ACE2 and monoclonal antibodies.

27 Nov 2020

Recurrent SARS-CoV-2 mutations do not significantly increase transmissibility, says study

A team of researchers at the Genetics Institute, University College London, tested whether any homoplasies observed in SARS-Cov-2 to date are significantly linked to increased viral transmission.

26 Nov 2020

Specific SARS-CoV-2 genomic variations are associated with higher COVID-19 deaths

A team of scientists from South Korea and the United States has conducted an interesting study to investigate whether mutations in the genome of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can affect the severity of coronavirus disease 2019 (COVID-19). The study findings reveal that mutations in the viral spike protein and RNA polymerase complex can increase the risk of COVID-19 mortality.

25 Nov 2020

Study: None of the SARS-CoV-2 mutations appear to increase transmissibility in humans

None of the mutations currently documented in the SARS-CoV-2 virus appear to increase its transmissibility in humans, according to a study led by UCL researchers.

25 Nov 2020

IU research could lead to improved breast cancer treatments for Black women

An Indiana University Melvin and Bren Simon Comprehensive Cancer Center researcher is identifying the unique biology that may make Black women more susceptible to aggressive breast cancer.

24 Nov 2020

UC Santa Cruz teams up to launch a web portal for people at risk of heritable stomach cancers

Coinciding with Stomach Cancer Awareness Month in November, the UC Santa Cruz Genomics Institute is teaming up with the patient advocacy nonprofit No Stomach For Cancer to release a web portal designed to help researchers identify individuals at risk of heritable stomach cancers.

24 Nov 2020

Researchers recommend antibody cocktail to tackle SARS-CoV-2 mutations

A new study released on the medRxiv* preprint server indicates that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent responsible for the current coronavirus disease 2019 (COVID-19) pandemic – is developing multiple mutations that affect neutralization by antibodies.

24 Nov 2020

Mutation News and Research

New combination therapy may help fight antimicrobial resistance

Research suggests plant flavonols could serve as effective antivirals for SARS-CoV-2

Study uncovers a promising therapeutic target for retinal dystrophies

Experimental stem cell gene therapy may give a new lease of life for patient with sickle cell disease

Clonal hematopoiesis linked to severe COVID-19

A mutant SARS-CoV-2 subspecies from minks may evade antibody detection

Adding exercise to genetic treatment reverses fatigue in mice with common myotonic dystrophy

SARS-CoV-2 spike protein shows slow but stable evolution, study finds

N439K mutation of SARS-CoV-2 may be more infectious and antibody resistant than Wuhan strain

Recurrent SARS-CoV-2 mutations do not significantly increase transmissibility, says study

Specific SARS-CoV-2 genomic variations are associated with higher COVID-19 deaths

Study: None of the SARS-CoV-2 mutations appear to increase transmissibility in humans

IU research could lead to improved breast cancer treatments for Black women

UC Santa Cruz teams up to launch a web portal for people at risk of heritable stomach cancers

Researchers recommend antibody cocktail to tackle SARS-CoV-2 mutations

Research provides key information on transmission, development of mutations in SARS-CoV-2 virus

Inherited DNA defects cause squamous cell carcinoma in kids with Fanconi anemia

Researchers develop new search engine to investigate viral sequences in COVID-19

Study shows BICRA gene functions in neural development in humans, flies

SARS-CoV-2's spike protein mutations have slowed, study finds

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

Latest News