Biopsy News and Research

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Biopsy is the removal of cells or tissues for examination by a pathologist. The pathologist may study the tissue under a microscope or perform other tests on the cells or tissue. There are many different types of biopsy procedures. The most common types include: (1) incisional biopsy, in which only a sample of tissue is removed; (2) excisional biopsy, in which an entire lump or suspicious area is removed; and (3) needle biopsy, in which a sample of tissue or fluid is removed with a needle. When a wide needle is used, the procedure is called a core biopsy. When a thin needle is used, the procedure is called a fine-needle aspiration biopsy.

Constant activation of p53 in hepatocytes of CLD patients could promote the development of liver cancer

p53 is one of the most important proteins in cancer biology. Often referred to as a "guardian of the genome," p53 becomes activated in response to various cellular stressors like DNA damage.

12 Jul 2022

Moffitt researchers discover kidney cancer-specific splicing variant biomarkers

Kidney cancer accounts for only 4% of all cancers in the United States; however, its incidence has more than doubled since 1975, with the most common type being clear cell renal cell carcinoma.

8 Jul 2022

A gentle, cost-effective method for breast cancer diagnosis

If breast cancer is suspected, doctors carry out a biopsy. However, this is invasive, painful and costly. It also takes several days to get the results.

4 Jul 2022

Bladder cancer patients with ctDNA positivity respond very well to treatment with atezolizumab

Researchers who treated a group of post-surgery bladder cancer patients with the immunotherapy drug atezolizumab have found that patients whose blood contained circulating tumour DNA (ctDNA), responded very well to the treatment.

3 Jul 2022

MRI scans can detect prostate cancer more accurately than new imaging technique

A team of researchers in Australia and New Zealand has found that MRI scans can detect prostate cancer more accurately than the newer, prostate-specific -PSMA PET/CT scanning technique.

3 Jul 2022

Greater global coordination needed for AI-enhanced diagnostics, treatment to save lives of prostate cancer patients

The largest prostate cancer biopsy dataset – involving over 95,000 images – has been created by researchers in Sweden to ensure AI can be trained to diagnose and grade prostate cancer for real world clinical applications.

3 Jul 2022

Nomogram helps predict anal cancer risk in HIV patients

Both cervical and anal cancer are caused by human papillomavirus. Both diseases also share a common precursor: abnormal cells known as high-grade squamous intraepithelial lesions (HSIL).

1 Jul 2022

New K+-sensitive dual-mode imaging probe for diagnosis of tumor malignancy

Tumor malignancy identification plays an essential role in clinical management of cancer. Currently, biopsy is the gold standard for malignancy identification in most tumor cases, it is, however, invasive that can cause great discomfort to patients, and potentially increase the risk of distant metastases due to the complex sampling process.

1 Jul 2022

Doctors tend to have unrealistic expectations of the success of multi-step medical procedures

Whether a woman is giving birth or a man is having a cancer biopsy, medical care is rarely straightforward. At any point, an unexpected complication can arise, particularly during treatments that require several steps.

27 Jun 2022

Studies discover multiple gene variants that contribute to the risk and severity of NAFLD in children

In a pair of overlapping studies, a diverse team of researchers, led by scientists at University of California San Diego School of Medicine, have deepened investigations into the genetic origins of nonalcoholic fatty liver disease (NAFLD) in children, describing multiple gene variants (including some previously unknown) that contribute to the risk of developing NAFLD and gene variants associated with the severity of the liver disease.

27 Jun 2022

Novel liquid biopsy test can quickly identify cancer DNA in patients with metastatic breast cancer

A novel, automated liquid biopsy test in development by researchers at the Johns Hopkins Kimmel Cancer Center can accurately detect the presence of cancer DNA in the blood of patients with metastatic breast cancer within five hours.

23 Jun 2022

Medical societies publish guidelines on how to treat pre-invasive lesions of the vulva

Four international medical societies have collaborated on consensus statements for physicians, published in the Journal of Lower Genital Tract Disease, about how to treat pre-invasive lesions of the vulva.

21 Jun 2022

Research may pave the way for a future test to diagnose ALS

Amyotrophic lateral sclerosis (ALS) is a progressive disease of the nervous system. It affects nerve cells in the brain and spinal cord called motor neurons.

21 Jun 2022

New liquid biopsy assay enables prediction of treatment response in patients with esophageal cancer

Biomarkers are like the X on a treasure map, but instead of indicating the location of unearthed riches, they indicate an individual's health status.

16 Jun 2022

Preventive care may be free, but follow-up diagnostic tests can bring big bills

When Cynthia Johnson learned she would owe $200 out-of-pocket for a diagnostic mammogram in Houston, she almost put off getting the test that told her she had breast cancer.

14 Jun 2022

New project seeks to develop a microscopy system for making drug interactions in the liver visible

Bielefeld University is coordinating a new EU-research project that seeks to produce microscopic liver tissue cultures that can survive for 14 days, while also using imaging methods to investigate how liver cells react to combinations of different medications.

14 Jun 2022

Ultrasound-based AI classifier of thyroid nodules can help rule out cancer, avoid unnecessary biopsies

Artificial intelligence (AI) can be used to identify thyroid nodules seen on thyroid ultrasound that are very unlikely to be cancerous, reducing a large number of unnecessary biopsies, according to a new study being presented Saturday at ENDO 2022, the Endocrine Society's annual meeting in Atlanta, Ga.

13 Jun 2022

New machine learning algorithm finds a gene signature characteristic of tumors

How do cancer cells differ from healthy cells? A new machine learning algorithm called "ikarus" knows the answer, reports a team led by MDC bioinformatician Altuna Akalin in the journal Genome Biology. The AI program has found a gene signature characteristic of tumors.

10 Jun 2022

Liquid biopsy could better predict immunotherapy response in lung cancer patients than tumor biopsy

Mount Sinai researchers have validated for the first time that a simple blood test called a liquid biopsy could be a better predictor of whether cancer immunotherapy will be successful for a patient with lung cancer than an invasive tumor biopsy procedure.

3 Jun 2022

Benefits and limitations of non-invasive tests for diagnosing non-alcoholic fatty liver disease

Non-alcoholic fatty liver disease (NAFLD) is among the most prevalent chronic liver disorders worldwide and can sometimes lead to severe conditions like cirrhosis and hepatocellular carcinoma.

2 Jun 2022

Biopsy News and Research

Further Reading

Constant activation of p53 in hepatocytes of CLD patients could promote the development of liver cancer

Moffitt researchers discover kidney cancer-specific splicing variant biomarkers

A gentle, cost-effective method for breast cancer diagnosis

Bladder cancer patients with ctDNA positivity respond very well to treatment with atezolizumab

MRI scans can detect prostate cancer more accurately than new imaging technique

Greater global coordination needed for AI-enhanced diagnostics, treatment to save lives of prostate cancer patients

Nomogram helps predict anal cancer risk in HIV patients

New K+-sensitive dual-mode imaging probe for diagnosis of tumor malignancy

Doctors tend to have unrealistic expectations of the success of multi-step medical procedures

Studies discover multiple gene variants that contribute to the risk and severity of NAFLD in children

Novel liquid biopsy test can quickly identify cancer DNA in patients with metastatic breast cancer

Medical societies publish guidelines on how to treat pre-invasive lesions of the vulva

Research may pave the way for a future test to diagnose ALS

New liquid biopsy assay enables prediction of treatment response in patients with esophageal cancer

Preventive care may be free, but follow-up diagnostic tests can bring big bills

New project seeks to develop a microscopy system for making drug interactions in the liver visible

Ultrasound-based AI classifier of thyroid nodules can help rule out cancer, avoid unnecessary biopsies

New machine learning algorithm finds a gene signature characteristic of tumors

Liquid biopsy could better predict immunotherapy response in lung cancer patients than tumor biopsy

Benefits and limitations of non-invasive tests for diagnosing non-alcoholic fatty liver disease

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