Next generation sequencing NGS News and Research

RSS

FDA issues emergency use authorization for T-Detect COVID Test

Today, the U.S. Food and Drug Administration issued an emergency use authorization for the T-Detect COVID Test developed by Adaptive Biotechnologies.

5 Mar 2021

Beckman Coulter Life Sciences Debuts Biomek NGeniuS Workstation at AGBT

Celebrating more than 85 years of innovation, Beckman Coulter Life Sciences announces its newest automated liquid handler, the Biomek NGeniuS workstation, at the virtual Advances in Genome Biology and Technology (AGBT) General Meeting.

From Beckman Coulter Life Sciences - Flow Cytometry 3 Mar 2021

Genetic testing technology wrongly detects the presence of very rare genetic variants

A technology that is widely used by commercial genetic testing companies is "extremely unreliable" in detecting very rare variants, meaning results suggesting individuals carry rare disease-causing genetic variants are usually wrong, according to new research published in the BMJ.

15 Feb 2021

Research shows rapid global spread of Southern California COVID-19 strain

A new strain of the coronavirus in Southern California, first reported last month by Cedars-Sinai, is rapidly spreading across the country and around the world as travelers apparently carry the virus with them to a growing list of global destinations, according to new research published today in the peer-reviewed Journal of the American Medical Association.

15 Feb 2021

Researchers detect traces of COVID-19 virus in sewage flowing from campus buildings

Although it is still challenging to prevent the transmission of COVID-19, researchers at the University of Miami are using all the strategies they can to fend off the spread.

10 Feb 2021

SPT Labtech Announces a Co-Marketing Initiative with Thermo Fisher Scientific to Help Reduce the Cost of NGS Library Prep

Initiative to promote the benefit of using Thermo Fisher Scientific’s library prep kits with SPT Labtech’s instruments to help reduce reagent and material requirements for high-throughput genome sequencing.

From SPT Labtech 3 Feb 2021

Gene panel is effective at identifying problematic genes in common leukemia

A gene panel that looks for about 10 times the number of cancer-causing genes as panels currently used to diagnose and fine-tune treatment for a variety of cancers is effective at identifying problematic genes in the most common leukemia, investigators report.

1 Feb 2021

Researchers release first Japanese reference genome

The Japanese now have their own reference genome thanks to researchers at Tohoku University who completed and released the first Japanese reference genome (JG1).

29 Jan 2021

New results challenge the current understanding of medulloblastoma

Scientists at St. Jude Children's Research Hospital and their colleagues have published a detailed account of SJMB03, a clinical trial for pediatric patients with medulloblastoma.

28 Jan 2021

A single genetic test can identify the presence and cause of mismatch repair deficiency

Researchers have developed a new integrated genetic/epigenetic DNA-sequencing protocol known as MultiMMR that can identify the presence and cause of mismatch repair (MMR) deficiency in a single test from a small sample of DNA in colon, endometrial, and other cancers.

21 Jan 2021

New coronavirus strain found in more than one-third of COVID-19 cases in Los Angeles

A new strain of the coronavirus has been found in more than one-third of COVID-19 cases in Los Angeles and may be contributing to the acceleration of the recent surge of cases across Southern California, according to new research from Cedars-Sinai.

19 Jan 2021

RECoVERY: New open-source software developed for analyzing SARS-CoV-2 genomes

Researchers report an open-source platform-independent tool for building SARS-CoV-2 genomes from raw sequencing reads. The tool can be used without any extra hardware or software and be run using any browser from a desktop or mobile.

19 Jan 2021

Study: NTRK fusions are far more frequently seen in pediatric tumors

In a large study of pediatric cancer patients, researchers from Children's Hospital of Philadelphia have analyzed the frequency, fusion partners, and clinical outcome of neurotrophic tyrosine receptor kinase (NTRK) fusions, which are clinical biomarkers that identify patients suitable for treatment with FDA-approved TRK inhibitors.

16 Jan 2021

Researchers establish BRIDGES program to synergize diagnostic efforts, patient outcome management

For over 20 years, the Genetics Service at the KK Women's and Children's Hospital (KKH) has been providing clinical care to patients with genetic disorders.

22 Dec 2020

South Korean city shows SARS-CoV-2 clade shift from V to GH over time

A new paper from South Korea describes the evolving SARS-CoV-2 genome in a single city, that of Gwangju, in the southwestern region of this country.

21 Dec 2020

Mogrify solidifies IP position surrounding core technology and expands platform algorithm to enhance cell conversion

Mogrify today announced it had secured the assignment of the foundational intellectual property underpinning its core direct cell conversion technology.

17 Dec 2020

SARS-CoV-2 unique deletion variants found in clinical specimens

While participating in the SPHERES Consortium project, US researchers sequenced 2,726 clinical patient specimens gathered in March 2020 and identified eight unique ORF7a deletion variants of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Their results are currently available on the bioRxiv* preprint server.

15 Dec 2020

Study findings can guide personalized breast cancer therapies based on melatonin

A Brazilian study published in the Journal of Pineal Research describes a group of genes potentially regulated by the hormone melatonin in some types of cancer, especially breast cancer.

8 Dec 2020

Researchers identify pathogenic organism that can transmit diseases in Bolson tortoise

The Bolson tortoise (Bolson Gopherus flavomarginatus) is the largest land reptile in North America. It lives mainly in dry areas, in particular, in the Chihuahua desert in northern Mexico. In recent decades, its numbers have fallen by 50%, driving the International Union for Conservation of Nature to include it on its red list and it has been classified as endangered.

4 Dec 2020

Scientists develop new bioinformatics pipeline to identify viruses in environmental samples

Researchers from the University of Helsinki have developed a novel bioinformatics pipeline called Lazy pipe for identifying viruses in host-associated or environmental samples.

3 Dec 2020