Inflammation News and Research

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CSF1R marker enables study of Macrophage Activation Mosaicism

Macrophages play a critical role in the immune system by fighting infections and aiding in tissue repair.

26 Jun 2024

Study finds women lost more of their body weight on average with semaglutide than men

Researchers performed a secondary analysis of the semaglutide treatment effect in people with obesity and heart failure with a preserved left ventricular ejection fraction program that included individuals with diabetes mellitus, stratified by biological sex.

26 Jun 2024

New drug tirzepatide significantly improves sleep apnea and weight loss

The effects of tirzepatide on adults with obesity and moderate-to-severe obstructive sleep apnea.

26 Jun 2024

Liquid core fibers offer long-term drug delivery in medical textiles

Treating a wound or an inflammation directly where it occurs has clear advantages: The active ingredient reaches its target immediately, and there are no negative side effects on uninvolved parts of the body.

26 Jun 2024

Nonhuman primate model reveals early-stage Alzheimer’s disease progression

Research in nonhuman primates is opening the possibility of testing treatments for the early stages of Alzheimer’s and similar diseases, before extensive brain cell death and dementia set in.

26 Jun 2024

“G900” gene enhancers may play a pivotal role in asthma-associated inflammation

Type-2 helper T (Th2) cells play intricate roles in the inflammatory response underlying asthma. Elevated levels of the protein GATA3 stimulate the maturation of these cells. Consequently, gene regions known as enhancers, which enhance the expression of the GATA3 gene, have been implicated in asthma-associated inflammation.

26 Jun 2024

Empathy intensifies negative health effects of conflict for kids

Children who report being more empathetic are more likely to show signs of poorer health in the face of more interparental conflict than less empathetic children, according to a new study led by researchers in the Penn State College of Health and Human Development.

26 Jun 2024

Semaglutide reduces heart risks in overweight and obese individuals without diabetes

The SELECT trial found that semaglutide significantly reduces cardiovascular events in individuals with overweight or obesity and preexisting cardiovascular disease, regardless of baseline HbA1c or changes in HbA1c levels.

26 Jun 2024

Novel genetic predisposition to being overweight or obese identified

Researchers performed a case-control study to compare metabolic changes between individuals homozygous for a loss-of-function genetic variation in small integral membrane protein 1 (SMIM1) and the general population.

25 Jun 2024

Research shows gut bacteria's role in mental resilience and reduced anxiety

Researchers characterized brain-gut microbiome (BGM) patterns related to stress resilience.

25 Jun 2024

Study links gene regulation to allergic airway inflammation

Asthma patients experience respiratory distress due to allergens like house dust mites or pollen. However, the various triggers for asthma share a common pathway involving the release of proteins called type-2 cytokines by Type-2 helper T (Th2) cells and group-2 innate lymphoid cells (ILC2s). Both Th2 and ILC2 require high amounts of GATA-binding protein 3 (GATA3) for their maturation.

25 Jun 2024

WEHI study reveals new methods in detecting necroptosis

Fully automated diagnostic techniques, including liquid handling robots, are poised to improve the lives of millions of people living with inflammatory diseases worldwide.

24 Jun 2024

New study in rhesus macaques offers early intervention window for Alzheimer's

Research in nonhuman primates is opening the possibility of testing treatments for the early stages of Alzheimer's and similar diseases, before extensive brain cell death and dementia set in.

24 Jun 2024

Study sheds light on the role of signaling pathway in the brain to prevent neuroinflammation

A new study led by University of Cincinnati researchers sheds new light on the role of a signaling pathway in the brain to maintain health and prevent inflammation and cognitive deficits.

24 Jun 2024

Using microbial community-scale metabolic modeling approach for precision nutrition

Short-chain fatty acids (SCFAs) are beneficial molecules created by the bacteria residing in our gut that are closely tied to improved host metabolism, lower systemic inflammation, better cardiovascular health, lower cancer risk, and more.

24 Jun 2024

New study reveals the therapeutic potential of ZED1227 in celiac disease

A recent study led by researchers at Tampere University investigated whether a transglutaminase 2 inhibitor has potential as a drug to treat celiac disease.

24 Jun 2024

Scientists identify potential driver of aggressive lung cancer in patients living in violent neighborhoods

Scientists have identified a potential driver of aggressive lung cancer tumors in patients who live in areas with high levels of violent crime.

24 Jun 2024

Using AI to improve gastroscopy diagnostics

During a gastroscopy, the oesophagus, stomach and duodenum are examined using an endoscope. This is a thin, flexible tube with a light and a camera at the tip.

24 Jun 2024

Semaglutide provides double benefit for women with heart failure

Semaglutide, a medication initially developed for type 2 diabetes and obesity, significantly improves symptoms in men and women with a common type of heart failure that has had few therapeutic options.

24 Jun 2024