Gene Expression News and Research

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Gene Expression is the process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.

Scientists create first detailed map of individual malaria parasite behavior

The first detailed map of individual malaria parasite behavior across each stage of its complicated life cycle has been created by scientists.

26 Aug 2019

Ketogenic diet shown to support intestinal stem cells

Scientists have discovered that ketone bodies produced during the ketogenic diet trigger the proliferation of intestinal stem cells in adults.

26 Aug 2019

Salk researchers develop new gene-editing tool to target broad range of mutations, cell types

The ability to edit genes in living organisms offers the opportunity to treat a plethora of inherited diseases. However, many types of gene-editing tools are unable to target critical areas of DNA, and creating such a technology has been difficult as living tissue contains diverse types of cells.

26 Aug 2019

Head-to-head comparison of three breast cancer drugs reveals important differences

Every year, more than 250,000 women in the U.S. are diagnosed with breast cancer. When detected early, patients with the most common form--which tests positive for hormone receptors (HR+) and negative for the HER2 receptor--usually respond well to treatment.

23 Aug 2019

Scientists identify unique way to treat incurable type of children's brain cancer

An international team of researchers led by Yale University, University of Iowa, and the Translational Genomics Research Institute, an affiliate of City of Hope, has discovered a new pathway that may improve success against an incurable type of children's brain cancer.

23 Aug 2019

Ludwig study uncovers novel vulnerability in MYC-driven cancers

A Ludwig Cancer Research study has uncovered a novel vulnerability in tumors that are driven by a common cancer gene known as MYC. Such cancers, it found, are highly dependent on the cell's machinery for making fats and other lipids.

22 Aug 2019

Research explains why many psychiatric drugs that work in the lab don’t work in people

Current drug development for neuropsychiatric disorders is in crisis, say experts. More than 90 percent of all drugs that are developed for illnesses like schizophrenia, depression, Alzheimer’s disease (AD), or the brain tumor glioblastoma complete successful trials in mice but then come to a grinding halt in human trials, wasting billions of dollars in drug research. This is partly because of obvious behavioral differences between the two species.

22 Aug 2019

Protein present in telomeres shows global action on genome which influences pleuripotency

Pluripotent cells can give rise to all cells of the body, a power that researchers are eager to control because it opens the door to regenerative medicine and organ culture for transplants.

21 Aug 2019

Protein implicated in neuron growth and cell adhesion appears crucial for pain sensitization

Researchers from Japan's Osaka University have made an important leap in our understanding of how chronic pain conditions develop.

20 Aug 2019

A new perspective on evolution provided by fly testes

The male testes are important areas for biological innovation, as well as being a factory for sperm. In exciting new biological research a team of scientists has found that the testes are also a hotspot for the production ofnew genes.

19 Aug 2019

Influenza A virus host range restricted by dysregulated expression of M gene segment

The host range of the influenza A virus is restricted by dysregulated expression of the M viral gene segment, according to a study published August 15 in the open-access journal PLOS Pathogens by Anice Lowen and John Steel of Emory University School of Medicine, and colleagues.

From PLOS ONE 16 Aug 2019

Simple technique to choose the sex of offspring by separating X and Y sperm

A simple, reversible chemical treatment can segregate X-bearing sperm from Y-bearing sperm, allowing dramatic alteration of the normal 50/50 male/female offspring ratio, according to a new study by Masayuki Shimada and colleagues at Hiroshima University, published on August 13 in the open-access journal PLOS Biology. The study was performed in mice, but the technique is likely to be widely applicable to other mammals as well.

From PLOS ONE 16 Aug 2019

Researchers gain new insights into the mechanism of vaccine-induced T cell immunity

A team led by the Walter Reed Army Institute of Research has gained new insights into the mechanism of vaccine-induced T cell immunity utilizing single-cell RNA sequencing and metabolic profiling techniques.

16 Aug 2019

UAMS Myeloma Center receives $542,486 grant from Leukemia & Lymphoma Society

Brian Walker, Ph.D., with the Myeloma Center at the University of Arkansas for Medical Sciences has received a $542,486, three-year grant from the Leukemia & Lymphoma Society to look at changes in the DNA sequence that effects the development and advancement of multiple myeloma, a cancer of plasma cells in the blood.

12 Aug 2019

Rhythms in gene expression are highly disrupted in the brains of people with schizophrenia

Rhythms in gene expression in the brain are highly disrupted in people with schizophrenia, according to a new University of Pittsburgh-led study.

10 Aug 2019

Researchers identify epigenetic mechanism that may strongly influence healthy aging

Researchers at the Max Delbrueck Center for Molecular Medicine have identified an epigenetic mechanism that appears to strongly influence healthy aging.

9 Aug 2019

Individual differences in pleasure are due to genetic variation, research suggests

Differences in how our brains respond when we're anticipating a financial reward are due, in part, to genetic differences, according to research with identical and fraternal twins published in Psychological Science, a journal of the Association for Psychological Science.

9 Aug 2019

Strong free-electron lasers can be used to break down amyloid protein aggregates

Amyloid fibrils are a type of self-assembled proteins/peptides that take on a stacked sheet-like formation. Amyloid fibril aggregates are known to be a cause of several diseases--including Alzheimer's--and therefore, it is of immense scientific interest to understand how these aggregates can be broken.

8 Aug 2019

New improved model for cancer wasting syndrome cachexia

A new model of cancer-related cachexia promises to help scientists understand why patients with cancer show severe wasting, which in turn may drive the development of better therapies.

7 Aug 2019

Pitt researchers first to grow genetically modified miniature human livers in the lab

Researchers at the University of Pittsburgh School of Medicine are the first to grow genetically modified miniature human livers in the laboratory, to emulate human liver disease progression and test therapeutics.

7 Aug 2019

Gene Expression News and Research

Further Reading

Scientists create first detailed map of individual malaria parasite behavior

Ketogenic diet shown to support intestinal stem cells

Salk researchers develop new gene-editing tool to target broad range of mutations, cell types

Head-to-head comparison of three breast cancer drugs reveals important differences

Scientists identify unique way to treat incurable type of children's brain cancer

Ludwig study uncovers novel vulnerability in MYC-driven cancers

Research explains why many psychiatric drugs that work in the lab don’t work in people

Protein present in telomeres shows global action on genome which influences pleuripotency

Protein implicated in neuron growth and cell adhesion appears crucial for pain sensitization

A new perspective on evolution provided by fly testes

Influenza A virus host range restricted by dysregulated expression of M gene segment

Simple technique to choose the sex of offspring by separating X and Y sperm

Researchers gain new insights into the mechanism of vaccine-induced T cell immunity

UAMS Myeloma Center receives $542,486 grant from Leukemia & Lymphoma Society

Rhythms in gene expression are highly disrupted in the brains of people with schizophrenia

Researchers identify epigenetic mechanism that may strongly influence healthy aging

Individual differences in pleasure are due to genetic variation, research suggests

Strong free-electron lasers can be used to break down amyloid protein aggregates

New improved model for cancer wasting syndrome cachexia

Pitt researchers first to grow genetically modified miniature human livers in the lab

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