Brain News and Research

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The human brain is the center of the human nervous system and is a highly complex organ. Enclosed in the cranium, it has the same general structure as the brains of other mammals, but is over three times as large as the brain of a typical mammal with an equivalent body size.

Anorexics’ brains are structurally and functionally altered

When people see pictures of bodies, a whole range of brain regions are active. This network is altered in women with anorexia nervosa. In a functional magnetic resonance imaging study, two regions that are important for the processing of body images were functionally more weakly connected in anorexic women than in healthy women.

25 Jan 2013

Researchers initiate first gene therapy clinical trial for Fabry disease

Researchers in Calgary have launched the first gene therapy clinical trial in the world for Fabry disease, a rare inherited enzyme deficiency that can shorten the lifespan of people who have it by as much as 40 years.

24 Jan 2013

New book discusses the basics of brain tumors

Empowering patients during the course of their treatment is the goal of a new book, Navigating Life with a Brain Tumor, written by neuro-oncologists from Mayo Clinic in Arizona and Tufts Medical Center in Boston.

24 Jan 2013

Sacral nerve stimulation helps manage children with chronic incontinence

Incontinence is typically a condition associated with adults; however, many children also struggle with incontinence - bladder, bowel or both. In order to help these children, doctors at Nationwide Children's Hospital have turned to a device, typically used in adult patients, to help manage children with chronic incontinence.

24 Jan 2013

Clinical trial to evaluate cyclodextrin against Niemann-Pick disease type C1

A clinical trial to evaluate a drug candidate called cyclodextrin as a possible treatment for Niemann-Pick disease type C1 (NPC), a rare and fatal genetic disease, will start today, researchers announced.

24 Jan 2013

Social isolation increases risk of addiction to amphetamine and alcohol

Rats that are socially isolated during a critical period of adolescence are more vulnerable to addiction to amphetamine and alcohol, found researchers at The University of Texas at Austin. Amphetamine addiction is also harder to extinguish in the socially isolated rats.

24 Jan 2013

Research team describes how the brain controls whisker movements in mice

All parents know the infant milestones: turning over, learning to crawl, standing, and taking that first unassisted step. Achieving each accomplishment presumably requires the formation of new connections among subsets of the billions of nerve cells in the infant's brain. But how, when and where those connections form has been a mystery.

24 Jan 2013

Researchers discover unique hairpin-like structure that facilitates Abeta clumping

Alzheimer's disease is the most common cause of late-life dementia. The disorder is thought to be caused by a protein known as the amyloid-beta protein, or Abeta, which clumps together in the brain, forming plaques that are thought to destroy neurons. This destruction starts early, too, and can presage clinical signs of the disease by up to 20 years.

24 Jan 2013

UTHealth NRC to sponsor forum on sports-related concussions

Super Bowl-winning lineman turned orthopaedic surgeon Mark Adickes, M.D., is moderating a free public forum to help parents, athletes and trainers spot the warning signs of concussion.

24 Jan 2013

Hyperbaric treatment restores neurological function in damaged brains

Stroke, traumatic injury, and metabolic disorder are major causes of brain damage and permanent disabilities, including motor dysfunction, psychological disorders, memory loss, and more. Current therapy and rehab programs aim to help patients heal, but they often have limited success.

23 Jan 2013

Study identifies how astrocytes regulate a neurotransmitter involved in sleep

Neuroscience researchers from Tufts University have found that our star-shaped brain cells, called astrocytes, may be responsible for the rapid improvement in mood in depressed patients after acute sleep deprivation. This in vivo study, published in the current issue of Translational Psychiatry, identified how astrocytes regulate a neurotransmitter involved in sleep.

23 Jan 2013

Genentech receives FDA approval for new use of Avastin plus chemotherapy to treat mCRC

Genentech, a member of the Roche Group, today announced that the U.S. Food and Drug Administration (FDA) has approved a new use of Avastin (bevacizumab) in combination with fluoropyrimidine-based irinotecan or oxaliplatin chemotherapy for people with metastatic colorectal cancer (mCRC).

23 Jan 2013

Researchers pinpoint several inherited mutations in autism

While autism clearly runs in some families, few inherited genetic causes have been found. A major reason is that these causes are so varied that it's hard to find enough people with a given mutation to establish a clear pattern. Researchers at Boston Children's Hospital have pinpointed several inherited mutations—among the first to be identified—through an unusual approach: using whole-exome sequencing to study large Middle Eastern families with autism.

23 Jan 2013

SMO and AKT1 mutations appear to drive about 15% of meningiomas

Large-scale genomic sequencing has revealed two DNA mutations that appear to drive about 15 percent of brain tumors known as meningiomas, a finding that could lead to the first effective drug treatments for the tumors, report scientists from Dana-Farber Cancer Institute and the Broad Institute.

23 Jan 2013

Trial to evaluate whether zolpidem reduces suicidal thinking in depressed insomniacs

Researchers want to know whether a sleeping pill reduces suicidal thoughts in depressed patients with insomnia.

23 Jan 2013

AANS, CNS join other medical societies in endorsing Protecting Seniors' Access to Medicare Act

The American Association of Neurological Surgeons (AANS) and Congress of Neurological Surgeons (CNS) joined 24 other medical societies in endorsing the "Protecting Seniors' Access to Medicare Act." Sponsored by Reps. Phil Roe, MD (R-TN) and Allyson Schwartz (D-PA), this bipartisan legislation would repeal the Independent Payment Advisory Board (IPAB), thereby protecting seniors from Medicare cuts that could threaten their access to care.

23 Jan 2013

UCLA researchers identify abnormal tau proteins associated with sports-related concussions

Sports-related concussions and mild traumatic brain injuries have grabbed headlines in recent months, as the long-term damage they can cause becomes increasingly evident among both current and former athletes. The Centers for Disease Control and Prevention estimates that millions of these injuries occur each year.

23 Jan 2013

Important updates on traumatic brain injury in military personnel

Researchers are making new strides in understanding the health consequences and treatment and rehabilitation needs of combat veterans and other service members affected by traumatic brain injury (TBI).

23 Jan 2013

UB scientists propose first genomic explanation for schizophrenia

New University at Buffalo research demonstrates how defects in an important neurological pathway in early development may be responsible for the onset of schizophrenia later in life.

23 Jan 2013

SLU team discovers molecular pathway that contributes to triple-negative breast cancer

In research published in the Jan. 17 issue of The Journal of Cell Biology, a team led by Susana Gonzalo, Ph.D., assistant professor of biochemistry and molecular biology at Saint Louis University, has discovered a molecular pathway that contributes to triple-negative breast cancer, an often deadly and treatment resistant form of cancer that tends to strike younger women.

23 Jan 2013