Clinical Trial News and Research

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Study examines the relationship between exclusive human milk consumption and gut microbiota in preterm infants

Researchers examine the impact of an exclusive human milk diet on the infant gut microbiome.

6 Mar 2023

High-dose anticoagulation can reduce deaths, intubations in hospitalized COVID-19 patients

High-dose anticoagulation can reduce deaths by 30 percent and intubations by 25 percent in hospitalized COVID-19 patients who are not critically ill when compared to the standard treatment, which is low-dose anticoagulation.

6 Mar 2023

LDL cholesterol levels reduced by oral PCSK9 inhibitor in phase 2 trial

MK-0616, an experimental oral proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor, met its primary endpoint and substantially reduced levels of low-density lipoprotein (LDL) cholesterol in people with high cholesterol and/or heart disease related to clogged arteries, in a study being presented at the American College of Cardiology's Annual Scientific Session Together With the World Congress of Cardiology.

6 Mar 2023

Clinical trial shows safety and immunogenicity of temperature-stable experimental TB vaccine

A clinical trial testing a freeze-dried, temperature-stable experimental tuberculosis (TB) vaccine in healthy adults found that it was safe and stimulated both antibodies and responses from the cellular arm of the immune system.

6 Mar 2023

New ablation technology successful at eliminating episodes of abnormal heart rhythms

A new ablation technology known as pulsed-field ablation was successful at eliminating episodes of abnormal heart rhythms for 12 months in up to two-thirds of patients, according to a study being presented at the American College of Cardiology's Annual Scientific Session Together With the World Congress of Cardiology.

6 Mar 2023

Transcatheter-based mitral valve repair safe and effective for nearly 9 out of 10 patients

The largest study to examine outcomes for patients treated outside a clinical trial setting with a minimally invasive procedure to repair a poorly functioning mitral valve in the heart found that the procedure was safe and resulted in a successful repair for nearly 9 out of 10 patients, researchers reported at the American College of Cardiology's Annual Scientific Session Together With the World Congress of Cardiology. Patients whose procedure was successful were half as likely to die within one year compared with those in whom the procedure was unsuccessful.

5 Mar 2023

Transcendental Meditation reduces stress-related burnout symptoms among healthcare providers

Healthcare providers (HCP) at three Miami hospitals during the height of the Covid crisis, who practiced the Transcendental Meditation technique (TM), showed a rapid and highly significant reduction in stress-related burnout symptoms such as somatization, depression, anxiety, sleep disturbances, and emotional exhaustion, as well as significant improvement in mental well-being, compared to a parallel matched lifestyle-as-usual group (LAU), according to a new study published today in PLOS ONE.

3 Mar 2023

Women’s heart disease pioneer receives the 2023 Master of the ACC Award

Noel Bairey Merz, MD, professor of cardiology and the director of the Barbra Streisand Women's Heart Center in the Smidt Heart Institute, will receive the 2023 Master of the ACC Award from the American College of Cardiology in honor of her pioneering contributions to the cardiovascular profession.

3 Mar 2023

Experts underscore the need for interventions to meet brain injury caregivers’ needs

Research on caregiving after neurotrauma and neurological disability extends the focus beyond individuals with neurological conditions to caregivers - family, friends, and significant others who also are also greatly impacted.

3 Mar 2023

Gene mutation capable of regulating pain discovered

Pain afflicts at least 1.5 billion people worldwide, and despite the availability of various painkilling drugs, not all forms of pain are treatable.

3 Mar 2023

Cardiac MRI can produce an accurate picture of the healthy heart in adolescence

The results, published in eClinicalMedicine, have direct implications for clinical practice by providing a list of reference values for a multitude of cardiac parameters used in daily practice.

3 Mar 2023

What are the clinical considerations of proton radiotherapy for individuals with locally advancing breast cancer?

In a recent review published in Current Oncology, researchers highlighted the technical and clinical considerations for proton radiotherapy delivery for individuals with locally advancing breast malignancies.

1 Mar 2023

Promising alternative strategy for islet transplantation in people with type 1 diabetes

In people with type 1 diabetes, the body's immune system attacks and destroys insulin-producing β cells that control blood glucose levels and are part of a group of cells in the pancreas called pancreatic islets.

1 Mar 2023

Clinical study reveals new use for high blood pressure drug in pediatric patients

A clinical study conducted by Indiana University School of Medicine researchers revealed that oral verapamil, a readily available and commonly used drug to treat high blood pressure and heart conditions, can also improve the pancreas' insulin secretion in children with newly-diagnosed type 1 diabetes (T1D).

1 Mar 2023

Researchers receive $15 million to study the brain processes involved in speech, epilepsy, and reading

Three grants totaling $15 million, which aim to enhance knowledge of the brain processes that play a key role in speech, epilepsy, and reading, have been awarded to researchers at UTHealth Houston by the National Institutes of Health Brain Research Through Advancing Neurotechnologies (BRAIN) Initiative.

1 Mar 2023

Covid-19 vaccination can curb the effect of long COVID on patients' social, professional, and family lives

Vaccination against SARS-CoV-2, the virus responsible for COVID-19, may lessen the severity and duration of 'long COVID' in those with persistent symptoms after infection, suggests a study that closely imitates a randomized clinical trial, and published in the open access journal, BMJ Medicine.

1 Mar 2023

Ultrasound device may help some hypertensive patients to keep blood pressure under control

A device that uses ultrasound to calm overactive nerves in the kidneys may be able to help some people get their blood pressure under control.

28 Feb 2023

Cutting just one food from the diet rather than six may help treat eosinophilic esophagitis

Eliminating animal milk alone from the diet of adults with eosinophilic esophagitis, or EoE, is as effective at treating the disease as eliminating animal milk plus five other common foods, a clinical trial funded by the National Institutes of Health has found.

27 Feb 2023

University of Miami researcher awarded $3.25 million DOD grant to treat male infertility after spinal cord injury

Emad Ibrahim, M.D., director of the Male Fertility Research Program at The Miami Project to Cure Paralysis and the clinical andrology lab at the Desai Sethi Urology Institute at the University of Miami Miller School of Medicine, has been awarded a $3.25 million grant by the Department of Defense for a four-year study on the use of an oral medication to treat an infertility issue that affects most men with spinal cord injury.

27 Feb 2023

Face blindness may be more common than currently believed

Face blindness, a mystifying condition that can trick us into believing we recognize people we've never met or make us fail to recognize those we have, has been previously estimated to affect between 2 and 2.5 percent of people in the world.

27 Feb 2023

Clinical Trial News and Research

Study examines the relationship between exclusive human milk consumption and gut microbiota in preterm infants

High-dose anticoagulation can reduce deaths, intubations in hospitalized COVID-19 patients

LDL cholesterol levels reduced by oral PCSK9 inhibitor in phase 2 trial

Clinical trial shows safety and immunogenicity of temperature-stable experimental TB vaccine

New ablation technology successful at eliminating episodes of abnormal heart rhythms

Transcatheter-based mitral valve repair safe and effective for nearly 9 out of 10 patients

Transcendental Meditation reduces stress-related burnout symptoms among healthcare providers

Women’s heart disease pioneer receives the 2023 Master of the ACC Award

Experts underscore the need for interventions to meet brain injury caregivers’ needs

Gene mutation capable of regulating pain discovered

Cardiac MRI can produce an accurate picture of the healthy heart in adolescence

What are the clinical considerations of proton radiotherapy for individuals with locally advancing breast cancer?

Promising alternative strategy for islet transplantation in people with type 1 diabetes

Clinical study reveals new use for high blood pressure drug in pediatric patients

Researchers receive $15 million to study the brain processes involved in speech, epilepsy, and reading

Covid-19 vaccination can curb the effect of long COVID on patients' social, professional, and family lives

Ultrasound device may help some hypertensive patients to keep blood pressure under control

Cutting just one food from the diet rather than six may help treat eosinophilic esophagitis

University of Miami researcher awarded $3.25 million DOD grant to treat male infertility after spinal cord injury

Face blindness may be more common than currently believed

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