Aging News and Research

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Shorter telomere length of leucocytes may signal heightened dementia risk

Shorter telomeres on the ends of white blood cell chromosomes may signal a heightened dementia risk, suggest the results of a large long term study, published online in the journal General Psychiatry.

12 Sep 2023

Unlocking the future of dementia: Your telomere length could predict your risk

The recent study in General Psychiatry found that leukocyte telomere length (LTL) is significantly associated with the risk of developing dementia, especially Alzheimer's disease. Using data from over 430,000 individuals, the study suggests that telomere length could serve as a predictive biomarker for brain health and dementia risk.

12 Sep 2023

SARS-CoV-2 infection can exacerbate production of auto-antibodies relating to auto-immune diseases

An article published in NPJ Aging, a Springer Nature journal, reveals that natural production of auto-antibodies increases with age and that infection by SARS-CoV-2 can exacerbate production of auto-antibodies relating to auto-immune diseases, helping to explain why aging increases the chances of developing severe COVID-19.

12 Sep 2023

New MRI technology promises to revolutionize understanding of iron homeostasis in the brain

Research team led by Shir Filo and Prof. Aviv Mezer of the Safra Center for Brain Science at the Hebrew University of Jerusalem (ELSC) and Dr. Tal Shahar currently, Director of the Neurosurgical Oncology Unit at the Neurosurgery Department, Tel Aviv Sourasky Medical Center, have unveiled a groundbreaking magnetic resonance imaging (MRI) technology that promises to revolutionize our understanding of iron homeostasis in the human brain.

12 Sep 2023

Smoking can accelerate the process of aging, study shows

A study of nearly 500,000 people has shown that smoking shortens the end fragments of chromosomes in the white blood cells of our immune systems.

12 Sep 2023

COPD hospitalizations rising sharply in Canada, especially among younger females

Annual hospital admissions for chronic obstructive pulmonary disease (COPD) in Canada increased 69% since 2002, especially in females and people under age 65, according to new research in CMAJ (Canadian Medical Association Journal) https://www.cmaj.ca/lookup/doi/10.1503/cmaj.221051.

11 Sep 2023

Research sheds light on the role of lipidome in human physiology

The sequencing of the human genome promised a revolution in medicine, but scientists soon realized that a genetic blueprint alone does not show the body in action.

11 Sep 2023

Buck Institute receives $3.5 million federal grant to lead clinical trial of ketone intervention in older adults

The Buck Institute for Research on Aging has received a $3.5 million federal grant to lead the first-ever double-blind, randomized, placebo-controlled clinical trial to understand the effects of ketone ester supplementation on frailty, a condition of vulnerability which develops following age-related decline in multiple physiological systems.

11 Sep 2023

Probation disproportionately affects the health outcomes of Black Americans

"Mistrust all in whom the impulse to punish is powerful," warned Friedrich Nietzsche more than a century ago.

11 Sep 2023

PI3K pathway rewiring drives prostate cancer growth

Experts in cell signaling at the Babraham Institute have identified how prostate cancer cells achieve cell growth free from the usual growth cues and regulators.

11 Sep 2023

A father dreamed of a home for his family. Medical debt nearly pushed them onto the streets.

Kayce Atencio used to be haunted by a thought while working at a homeless shelter in downtown Denver. "It could have been me," said Atencio, 30, who lives in a small apartment with his son and daughter not far from the shelter.

11 Sep 2023

Dietary cholesterol and fruit tannins synergistically promote kidney stone formation

Kidney stones (KS), hard crystalline formations that occur within the kidney, are a common condition that affects millions of people worldwide.

11 Sep 2023

Research shines light on early life factors that may increase risk of cardiovascular disease in women

Advanced research is casting light on possible early life factors – including poverty, physical or mental abuse – that may impact the rate of egg loss and increase the risk of cardiovascular disease in post-menopausal women.

9 Sep 2023

Irisin-based therapies may help combat Alzheimer’s disease

Researchers who previously developed the first 3D human cell culture models of Alzheimer's disease (AD) that displays two major hallmarks of the condition - the generation of amyloid beta deposits followed by tau tangles - have now used their model to investigate whether the exercise-induced muscle hormone irisin affects amyloid beta pathology.

8 Sep 2023

Senolytic therapy in mild Alzheimer’s disease shows safety in phase I trial

Researchers conducted the phase 1 trial of orally-administered senolytic therapy comprising quercetin (Q) and dasatinib (D) for symptomatic and early-stage Alzheimer's disease (AD) patients.

8 Sep 2023

Cardiometabolic risk factors exponentially raise CVD incidence and mortality rates: a call for comprehensive management

The impact of individual and combined cardiometabolic risk factors on cardiovascular disease (CVD) incidence.

8 Sep 2023

Does caffeine interact with genetic risk factors for Parkinson's disease in Asians?

The interaction of caffeine with Leucine rich repeat kinase 2 (LRRK2) genetic risk variants in Asians.

8 Sep 2023

Phase I trial of senolytic therapy shows promise in Alzheimer's disease

Alzheimer's disease is the most common cause of dementia that affects more than 6.5 million Americans, according to the Alzheimer's Association.

8 Sep 2023

Study shows substantial impact of the pandemic on mental health of older adults with cancer

Older adults who have had cancer had a high risk of experiencing symptoms of depression during the early months of the COVID-19 pandemic according to a new study published in Cancer Management and Research.

7 Sep 2023

Rethinking menopause: Experts call for individualized treatment and more research

A comprehensive review in the journal Cell provides an in-depth look at the biology, clinical outcomes, and treatment options for menopause, including the effects of hormonal changes on metabolic and cognitive functions. The article also discusses various therapeutic interventions, from hormone therapy to alternative medicines, and their efficacy in managing menopausal symptoms.

7 Sep 2023

Aging News and Research

Shorter telomere length of leucocytes may signal heightened dementia risk

Unlocking the future of dementia: Your telomere length could predict your risk

SARS-CoV-2 infection can exacerbate production of auto-antibodies relating to auto-immune diseases

New MRI technology promises to revolutionize understanding of iron homeostasis in the brain

Smoking can accelerate the process of aging, study shows

COPD hospitalizations rising sharply in Canada, especially among younger females

Research sheds light on the role of lipidome in human physiology

Buck Institute receives $3.5 million federal grant to lead clinical trial of ketone intervention in older adults

Probation disproportionately affects the health outcomes of Black Americans

PI3K pathway rewiring drives prostate cancer growth

A father dreamed of a home for his family. Medical debt nearly pushed them onto the streets.

Dietary cholesterol and fruit tannins synergistically promote kidney stone formation

Research shines light on early life factors that may increase risk of cardiovascular disease in women

Irisin-based therapies may help combat Alzheimer’s disease

Senolytic therapy in mild Alzheimer’s disease shows safety in phase I trial

Cardiometabolic risk factors exponentially raise CVD incidence and mortality rates: a call for comprehensive management

Does caffeine interact with genetic risk factors for Parkinson's disease in Asians?

Phase I trial of senolytic therapy shows promise in Alzheimer's disease

Study shows substantial impact of the pandemic on mental health of older adults with cancer

Rethinking menopause: Experts call for individualized treatment and more research

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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