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HIF1 protein identified as key driver of tendon pain

Overuse of our tendons can cause painful medical conditions for which only limited treatment options exist. Researchers have now deciphered an important molecular mechanism that triggers these problems.

14 Jan 2026

Disease-responsive nanoparticles enable ghrelin mRNA therapy in osteoarthritis

Nitin Joshi, PhD, and Jingjing Gao, PhD, of the Department of Anesthesiology at Mass General Brigham, are the co-senior authors of a paper published in Nature Nanotechnology, "A disease-severity-responsive nanoparticle enables potent ghrelin mRNA therapy in osteoarthritis." Mahima Dewani, PhD, is the lead author of this study.

14 Jan 2026

WSU study reveals gaps in end-of-life care education for doctors

Doctors encounter death and dying significantly more than most people. It's the price of saving lives and helping people.

14 Jan 2026

PFAS exposure linked to gestational diabetes and insulin problems

Exposure to per- and polyfluoroalkyl substances (PFAS), a class of highly persistent environmental chemicals commonly referred to as "forever chemicals," is associated with a higher risk of gestational diabetes mellitus and altered markers of insulin resistance and insulin secretion, according to a new systematic review and meta-analysis led by researchers at the Icahn School of Medicine at Mount Sinai.

14 Jan 2026

DLL3 on circulating tumor cells predicts tarlatamab success in lung cancer

A team led by investigators at the Mass General Brigham Cancer Institute has discovered that a particular marker on tumor cells circulating in the blood indicates whether a patient with lung cancer will experience a lasting response to a newly approved immunotherapy called tarlatamab.

14 Jan 2026

New BIND screener identifies brain-related comorbidities risk in Duchenne muscular dystrophy

In research published in Developmental Medicine & Child Neurology, investigators developed a brief, reliable, and valid screening tool to help identify individuals with Duchenne muscular dystrophy (a neuromuscular disorder) who are at increased risk of brain-related comorbidities, such as language disorders, attention-deficit/hyperactivity disorder, and anxiety.

14 Jan 2026

New metabolomic signature predicts type 2 diabetes risk beyond traditional factors

Diabetes, a metabolic disease, is on the rise worldwide, and over 90 percent of cases are type 2 diabetes, where the body does not effectively respond to insulin.

14 Jan 2026

Research shows racial-ethnic differences in the risk of pregnancy-related high blood pressure

The risk of pregnancy-related high blood pressure varied markedly among subgroups of Asian American, Native Hawaiian and Pacific Islander people, highlighting the need for tailored prevention and treatment, according to research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

14 Jan 2026

Vaccines are helping older people more than we knew

Let's be clear: The primary reason to be vaccinated against shingles is that two shots provide at least 90% protection against a painful, blistering disease that a third of Americans will suffer in their lifetimes, one that can cause lingering nerve pain and other nasty long-term consequences.

14 Jan 2026

States race to launch rural health transformation plans

Imagine starting the new year with the promise of at least a $147 million payout from the federal government.

14 Jan 2026

New mouse model enables study of chronic lung infections in aging

Respiratory infections are among the leading causes of illness and death in the elderly, driven by immune aging, chronic diseases, and reduced physiological resilience.

13 Jan 2026

More surgical patients on opioid use disorder treatment demand updated pain care

As more Americans receive treatment for opioid use disorder, that progress is increasingly showing up in the operating room, creating an urgent need to modernize how pain is managed during and after major surgery, according to a study in the February 2026 issue of Anesthesiology, the peer-reviewed medical journal of the American Society of Anesthesiologists (ASA).

13 Jan 2026

New European initiative aims to transform real world Alzheimer’s disease care

Today, the ACCESS-AD consortium is announcing the launch of a transformative European initiative that will accelerate the implementation of scientific innovations for Alzheimer's disease (AD) management in real-world health systems.

13 Jan 2026

Novel antibody shows promise in overcoming resistance to cancer immunotherapy

According to a Phase I study led by researchers at The University of Texas MD Anderson Cancer Center, published today in Nature Medicine, the novel monoclonal antibody linavonkibart demonstrated the potential to overcome treatment resistance to anti-PD-1 immune checkpoint inhibitors in multiple cancer types.

13 Jan 2026

Preclinical study reveals potential new treatment for severe liver fibrosis

Researchers at McMaster University are leading preclinical studies into a novel drug candidate developed by Espervita Therapeutics that has the potential to prevent and reverse liver fibrosis - a dangerous, disease-induced build-up of scar tissue in the liver that often leads to cancer.

13 Jan 2026

Novel immunotherapy targeting pancreatic cancer shows promising results in phase 1/2 trial

A recent publication in Nature Medicine describes a novel immunotherapy targeting pancreatic cancer that has shown promising results in a first in-human phase 1/2 trial.

13 Jan 2026

Implanted vagus nerve stimulation device offers lasting relief for severe depression

About 20% of U.S. adults experience major depression in their lifetime. For most people, symptoms improve within a few treatment attempts, but up to one-third of patients have treatment-resistant depression, for which standard antidepressant medication or psychotherapy isn't enough.

13 Jan 2026

Higher maternal blood pressure linked to increased risks of pregnancy complications

Helping women to keep their blood pressure at normal levels could reduce their risk of experiencing pregnancy complications, according to a new study led by researchers at the University of Bristol. The research is published in BMC Medicine today [14 January].

13 Jan 2026

New open access guide helps parents and coaches spot youth concussions

An international group of researchers has put together an easy-to-follow guide for parents and coaches to recognize concussions in young athletes and respond appropriately.

13 Jan 2026

Obesity study reveals gut fat's unique inflammatory role and immune cell richness

Abdominal fat is not a uniform tissue. A new study from Karolinska Institutet, Steno Diabetes Center Copenhagen, and Helmholtz Munich reveals that fat located close to the large intestine contains an unusually high number of inflammatory fat cells and immune cells.

13 Jan 2026

Medicine News and Research

HIF1 protein identified as key driver of tendon pain

Disease-responsive nanoparticles enable ghrelin mRNA therapy in osteoarthritis

WSU study reveals gaps in end-of-life care education for doctors

PFAS exposure linked to gestational diabetes and insulin problems

DLL3 on circulating tumor cells predicts tarlatamab success in lung cancer

New BIND screener identifies brain-related comorbidities risk in Duchenne muscular dystrophy

New metabolomic signature predicts type 2 diabetes risk beyond traditional factors

Research shows racial-ethnic differences in the risk of pregnancy-related high blood pressure

Vaccines are helping older people more than we knew

States race to launch rural health transformation plans

New mouse model enables study of chronic lung infections in aging

More surgical patients on opioid use disorder treatment demand updated pain care

New European initiative aims to transform real world Alzheimer’s disease care

Novel antibody shows promise in overcoming resistance to cancer immunotherapy

Preclinical study reveals potential new treatment for severe liver fibrosis

Novel immunotherapy targeting pancreatic cancer shows promising results in phase 1/2 trial

Implanted vagus nerve stimulation device offers lasting relief for severe depression

Higher maternal blood pressure linked to increased risks of pregnancy complications

New open access guide helps parents and coaches spot youth concussions

Obesity study reveals gut fat's unique inflammatory role and immune cell richness

Everything there is to know about biosimilars eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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