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Study provides a better understanding of the complex interplay of ncRNAs with gene regulation

Researchers at the University of Eastern Finland have discovered previously unknown non-coding RNAs (ncRNAs) involved in regulating the gene expression of vascular endothelial growth factors (VEGF), the master regulators of angiogenesis.

6 May 2021

Salesforce, Google, Facebook. How big tech undermines California’s public health system.

California Gov. Gavin Newsom has embraced Silicon Valley tech companies and health care industry titans in response to the covid-19 pandemic like no other governor in America — routinely outsourcing life-or-death public health duties to his allies in the private sector.

6 May 2021

Researchers identify new immunotherapy treatment target for acute myeloid leukemia in children

Researchers have identified a gene expressed in children with acute myeloid leukemia (AML) that could serve as a new immunotherapy treatment target, according to a new study published today in Blood Advances, a journal of the American Society of Hematology.

5 May 2021

Penn State researchers develop a way to study microenvironment of breast cancer in 3D

Cancerous tumors thrive on blood, extending their roots deep into the fabric of the tissue of their host. They alter the genetics of surrounding cells and evolve to avoid the protective attacks of immune cells.

4 May 2021

Study investigates how Brd4 influences diet-induced obesity

A new study, published in JCI Insight, looks at how Brd4, a regulator of the innate immune response, influences diet-induced obesity.

4 May 2021

Scientists identify genetic mutation associated with exfoliation syndrome known to cause glaucoma

A team of researchers from the Agency for Science, Technology and Research's Genome Institute of Singapore and Bioprocessing Technology Institute, as well as Singapore Eye Research Institute, have identified a genetic mutation (functionally defective CYP39A1 gene) associated with exfoliation syndrome, the most common cause of glaucoma.

4 May 2021

New drug class effective in treating certain types of ovarian cancers

A study published today in Nature Communications shows that the drug rucaparib has been effective in treating certain types of ovarian cancers if used early in treatment, after a diagnosis, and before the cancer cells build up a resistance to chemotherapy.

4 May 2021

Proteomic and transcriptomic profiling provide a full picture of aging process in the kidneys

Studying protein changes in the kidneys as we age, as well as the transcription of genes into proteins, helps provide a full picture of the age-related processes that take place in these organs, says a study in mice published today in eLife.

4 May 2021

Rucaparib drug is effective in treating certain types of ovarian cancers, shows study

4 May 2021

SARS-CoV-2 spike mutations during transmission among humans and to animals

A fascinating new study discusses the 40 mutations that are seen on the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein and their potential effects on viral biology.

3 May 2021

COVID-19 may not have appeared first in China, suggests new genomic study

A new study in Acta Mathematica Scientia suggests that the virus may have originated in multiple countries almost simultaneously, rather than spreading from China to the rest of the world.

3 May 2021

A new SARS-CoV-2 variant (HMN.19B) has been identified in France

New research published in the Centers for Disease Control and Prevention’s journal Emerging Infectious Diseases has confirmed the emergence of a new SARS-CoV-2 variant called HMN.19B from the viral clade 19B in France. The 19B viral clade — which includes the D614G variant — was prevalent in late 2019 but had since been rarely observed since early 2020 because of newer viral clades.

3 May 2021

Comprehensive "cell atlas" shows how COVID-19 can lead to organ failure and death

Scientists from several hospitals and research centers have shown what happens in individual cells of patients who died of COVID-19. In a study published in Nature, the researchers describe how infected cells from multiple organs exhibited a range of molecular and genomic changes.

3 May 2021

Researchers identify novel SARS-CoV-2 variant with mutations in membrane protein-encoding gene

A recent study published in the Journal Emerging Microbes and Infections has highlighted the emergence of a novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variant with mutations in the membrane protein-encoding gene. Two potential mutations, M:I82T and M:V70L, have been identified within the transmembrane helices, which are expected to improve viral fitness by modulating glucose uptake during replication.

3 May 2021

Correcting mutations in muscle stem cells using new gene-editing technology

A new gene-editing technique can be used to correct mutations in muscle stem cells, paving the way for the first potential cell therapy for genetic muscle disorders.

30 Apr 2021

Novel integrative genetic screening platform offers insights into role of DNA accessibility in cancer

In a new resource for the scientific community, published today in Nature Biotechnology, researchers in the lab of Neville Sanjana, PhD, at the New York Genome Center (NYGC) and New York University (NYU) developed CRISPR-sciATAC, a novel integrative genetic screening platform that jointly captures CRISPR gene perturbations and single-cell chromatin accessibility genome-wide.

30 Apr 2021

Immunocompromised children and young adults may experience prolonged SARS-CoV-2 infection

Children and young adults with compromised immune systems, such as those undergoing cancer treatment, may experience a prolonged period of infection with SARS-CoV-2, the virus that causes COVID-19, and the extended duration of infection may increase the incidence of mutations.

29 Apr 2021

Researchers apply 'kitchen sink approach' to produce 16 high-quality reference genomes

The flightless kakapo of New Zealand is in trouble. The world's heaviest parrot--representing one of the most ancestral branches of the parrot family tree--is nearly extinct, with barely 200 adults plodding the underbrush of four small islands.

29 Apr 2021

Researchers try to simplify gene nomenclature across various organisms

Constantina Theofanopoulou wanted to study oxytocin. Her graduate work had focused on how the hormone influences human speech development, and now she was preparing to use those findings to investigate how songbirds learn to sing. The problem was that birds do not have oxytocin. Or so she was told.

29 Apr 2021

Researchers propose a new universal nomenclature for vasotocin and oxytocin genes

Oxytocin and arginine vasopressin are two hormones in the endocrine system that can act as neurotransmitters and regulate -in vertebrates and invertebrates- a wide range of biological functions, such as bonding formation, breastfeeding, birth or arterial pressure.

29 Apr 2021

Genomic News and Research

Study provides a better understanding of the complex interplay of ncRNAs with gene regulation

Salesforce, Google, Facebook. How big tech undermines California’s public health system.

Researchers identify new immunotherapy treatment target for acute myeloid leukemia in children

Penn State researchers develop a way to study microenvironment of breast cancer in 3D

Study investigates how Brd4 influences diet-induced obesity

Scientists identify genetic mutation associated with exfoliation syndrome known to cause glaucoma

New drug class effective in treating certain types of ovarian cancers

Proteomic and transcriptomic profiling provide a full picture of aging process in the kidneys

Rucaparib drug is effective in treating certain types of ovarian cancers, shows study

SARS-CoV-2 spike mutations during transmission among humans and to animals

COVID-19 may not have appeared first in China, suggests new genomic study

A new SARS-CoV-2 variant (HMN.19B) has been identified in France

Comprehensive "cell atlas" shows how COVID-19 can lead to organ failure and death

Researchers identify novel SARS-CoV-2 variant with mutations in membrane protein-encoding gene

Correcting mutations in muscle stem cells using new gene-editing technology

Novel integrative genetic screening platform offers insights into role of DNA accessibility in cancer

Immunocompromised children and young adults may experience prolonged SARS-CoV-2 infection

Researchers apply 'kitchen sink approach' to produce 16 high-quality reference genomes

Researchers try to simplify gene nomenclature across various organisms

Researchers propose a new universal nomenclature for vasotocin and oxytocin genes

Genetics & Genomics - Second Edition eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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