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UofL researchers receive $11.7 million to study microorganisms throughout the body

University of Louisville researchers have received $11.7 million to study microorganisms throughout the body, including the mouth. What they find could lead to better understanding and treatment of a range of chronic conditions.

25 Aug 2023

New 3D model mimics brain cell and immune cell interactions in Alzheimer's disease

Cognitive decline associated with Alzheimer's disease (AD) develops when neurons begin to die, which can be caused by inappropriate immune responses and excessive inflammation in the brain triggered by amyloid beta deposits and tau tangles, two hallmarks of the disease.

25 Aug 2023

UK Biobank Dementia Risk Score outperforms other widely used scores

A new dementia risk score, which draws on 11 mostly modifiable risk factors, identifies people at risk—from mid-life onwards—of developing the disease within the next 14 years, suggests a large long-term study published in the open access journal BMJ Mental Health.

25 Aug 2023

Cholesterol loss in inner ear linked to age-related hearing loss

Researchers led by María Eugenia Gomez-Casati, the Institute of Pharmacology, School of Medicine, University of Buenos Aires-CONICET; Mauricio Martin, the Institute of Medical Research Mercedes; and Martín Ferreyra, (INIMEC-CONICET-UNC), National University of Córdoba in Argentina report that age-related hearing loss is associated with a decrease of cholesterol in the inner ear.

24 Aug 2023

People over 60s with the unhealthiest lifestyles more likely to require nursing home admission

Over 60s with the unhealthiest lifestyles are significantly more likely to require admission to a nursing home than their peers with the healthiest lifestyles, suggest the findings of a large population study published online in the Journal of Epidemiology & Community Health.

24 Aug 2023

Women with pre-eclampsia undergo accelerated aging during pregnancy

Pre-eclampsia, a life-threatening surge in blood pressure, is an enigmatic condition. Each year, it causes the deaths of more than 70,000 women worldwide. Because scientists do not know what causes it, they lack targeted strategies to treat it.

24 Aug 2023

Diabetes drug promotes longevity by stimulating the body's production of ether lipids

Metformin, the most commonly used drug to treat type 2 diabetes, not only lowers blood sugar levels but has revealed to extend lifespan in C. Elegans -- an animal model that shares similar metabolic systems with humans and are often used to model human diseases.

23 Aug 2023

Naked mole rat gene boosts health and longevity in mice

In a groundbreaking endeavor, researchers at the University of Rochester have successfully transferred a longevity gene from naked mole rats to mice, resulting in improved health and an extension of the mouse's lifespan.

23 Aug 2023

New gene variant linked to Parkinson's disease found in people of African ancestry

A gene variant found almost exclusively in the genomes of people of African ancestry increases the risk of developing Parkinson's disease, according to an international study of nearly 198,000 participants with this genetic background.

23 Aug 2023

NIH awards $3 million grant to study synbiotic medical food for bone health in older women

The NIH/National Institute on Aging has awarded a R01 $3 million grant to study the impact of a probiotic/prebiotic (synbiotic) medical food developed by Solarea Bio on maintaining bone health of older women.

23 Aug 2023

New study to investigate link between agricultural fire smoke and dementia risk

Worldwide, the practice of preparing agricultural fields by burning crop residue contributes large quantities of gaseous pollutants and aerosol particles to the atmosphere and is a known cardiorespiratory health hazard.

23 Aug 2023

Catheter ablation linked to lower risk of dementia in all patients with atrial fibrillation

Previous studies have shown a link between catheter ablation and a lower risk of dementia and premature death for patients with atrial fibrillation.

23 Aug 2023

Taking adult education classes may help prevent dementia

How can we best keep our brain fit as we grow older? It's well known that regular cognitive activity, for example brainteasers, sudokus, or certain video games in middle and old age tends to protect against cognitive decline and dementias like Alzheimer's.

23 Aug 2023

CPAP therapy can mitigate telomere shortening in sleep apnea patients

Obstructive sleep apnea (OSA) consists of multiple episodes of partial or complete closure of the upper airway that occur during sleep, leading to breathing cessation lasting more than ten seconds and sometimes even several minutes, followed by arousals and deep breathing.

23 Aug 2023

New digital biomarker could detect Alzheimer's disease in its earliest stages

Researchers from the University of Colorado Anschutz Medical Campus and Washington University in St. Louis have identified a way to assess brain activity in sleep that occurs in the earliest stages of Alzheimer's disease, typically many years prior to developing symptoms of dementia.

23 Aug 2023

UT Health San Antonio and partners secure NIH funding to translate scientific discoveries into therapeutic benefits

The University of Texas Health Science Center at San Antonio (also called UT Health San Antonio) and seven regional collaborators will leverage $46 million from the National Institutes of Health (NIH) over the next five to seven years to translate scientific discoveries into therapeutic benefits for human health and well-being.

22 Aug 2023

Gut-first theory of Parkinson's disease gains traction

Ask any neurologist: Parkinson's disease is a brain disorder. The conspicuous symptoms of Parkinson's disease - uncontrollable tremors, slowed down motions, and the feeling that one's feet are stuck to the ground - all stem from the loss of neurons in a region of the brain that helps control movement.

22 Aug 2023

Aging News and Research

UofL researchers receive $11.7 million to study microorganisms throughout the body

New 3D model mimics brain cell and immune cell interactions in Alzheimer's disease

UK Biobank Dementia Risk Score outperforms other widely used scores

Cholesterol loss in inner ear linked to age-related hearing loss

People over 60s with the unhealthiest lifestyles more likely to require nursing home admission

Women with pre-eclampsia undergo accelerated aging during pregnancy

Diabetes drug promotes longevity by stimulating the body's production of ether lipids

Naked mole rat gene boosts health and longevity in mice

New gene variant linked to Parkinson's disease found in people of African ancestry

NIH awards $3 million grant to study synbiotic medical food for bone health in older women

New study to investigate link between agricultural fire smoke and dementia risk

Catheter ablation linked to lower risk of dementia in all patients with atrial fibrillation

Taking adult education classes may help prevent dementia

CPAP therapy can mitigate telomere shortening in sleep apnea patients

New digital biomarker could detect Alzheimer's disease in its earliest stages

UT Health San Antonio and partners secure NIH funding to translate scientific discoveries into therapeutic benefits

Gut-first theory of Parkinson's disease gains traction

Max Planck Florida receives NIH funding to investigate the neural circuits underlying Alzheimer's disease

High-fat diet changes gut bacteria, bile acids, and increases colorectal cancer risk

Many older adults show interest in getting vaccinated against respiratory syncytial virus

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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