Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

Researchers identify alternate chemistry that could account for Alzheimer's pathologies

Alzheimer's disease, the most common cause of dementia among the elderly, is characterized by plaques and tangles in the brain, with most efforts at finding a cure focused on these abnormal structures.

13 Aug 2019

Engineers develop tissue model that mimics beta-amyloid's effects on blood-brain barrier

Beta-amyloid plaques, the protein aggregates that form in the brains of Alzheimer's patients, disrupt many brain functions and can kill neurons.

13 Aug 2019

Alzheimer's disease attacks brain regions responsible for wakefulness

Researchers and caregivers have noted that excessive daytime napping can develop long before the memory problems associated with Alzheimer's disease begin to unfold.

13 Aug 2019

Psychiatric symptoms may indicate the beginning of Alzheimer’s disease

Researchers at UC San Francisco (UCSF) and the University of São Paulo have shown that the earliest stages of Alzheimer’s brain pathology are tightly linked to neuropsychiatric symptoms such as anxiety, depression and sleep disturbances.

12 Aug 2019

Excessive daytime sleeping could be an early sign of Alzheimer’s

Excessive daytime napping often develops long before the memory problems associated with Alzheimer's disease occur. Now, researchers may have found the striking new biological explanation for this phenomenon.

12 Aug 2019

Regular, moderate exercise appears to prevent development of physical signs of Alzheimer's

Moderate exercise is not only good for memory as people age, it also appears to help prevent the development of physical signs of Alzheimer's, known as biomarkers, in those who are at risk for the disease, according to research presented at the annual convention of the American Psychological Association.

10 Aug 2019

Depression symptoms together with AD pathology could trigger changes in memory and thinking

Increasingly, Alzheimer's disease research has focused on the preclinical stage, when people have biological evidence of AD but no or minimal symptoms, and when interventions might have the potential to prevent future decline of older adults.

10 Aug 2019

Researchers identify direct toxic action of beta-amyloid in the brain

The brains of Alzheimer's patients who have already developed clinical symptoms contain large clumps of the protein beta-amyloid, known as plaques. Many therapeutic approaches focus on removing plaques, but such attempts have met with only limited success to date.

9 Aug 2019

Strong free-electron lasers can be used to break down amyloid protein aggregates

Amyloid fibrils are a type of self-assembled proteins/peptides that take on a stacked sheet-like formation. Amyloid fibril aggregates are known to be a cause of several diseases--including Alzheimer's--and therefore, it is of immense scientific interest to understand how these aggregates can be broken.

8 Aug 2019

New Zealand study shows positive effect of music and dance on older adults with dementia

Stereotypically viewed as passive and immobile, a University of Otago, New Zealand, pilot study has shown the powerful influence music and dance can have on older adults with dementia.

8 Aug 2019

New initiative launched to support development and application of psychology research

In recent years, efforts to understand the workings of the mind have taken on new-found urgency. Not only are psychological and neurological disorders -- from Alzheimer's disease and strokes to autism and anxiety -- becoming more widespread, new tools and methods have emerged that allow scientists to explore the structure of, and activity within, the brain with greater granularity.

7 Aug 2019

APOE gene variant may be protective and prolong life, finds study

A new study of 38,537 persons of European ancestry suggests that a rare variation of a gene called APOE may be protective and prolong life, in sharp contrast to a more widely studied APOE variant that increases risk of death.

7 Aug 2019

Japanese scientists develop new method to construct 3D models from 2D images

Japanese scientists report in Pattern Recognition a new method to construct 3D models from 2D images. The approach, which involves non-rigid registration with a blending of rigid transforms, overcomes several of the limitations in current methods.

6 Aug 2019

Amyloid PET scan is not an effective method for measuring severity, progression of Alzheimer's

While the presence of beta-amyloid plaques in the brain may be a hallmark of Alzheimer's disease, giving patients an amyloid PET scan is not an effective method for measuring their cognitive function, according to a new study from researchers in the Perelman School of Medicine at the University of Pennsylvania and Thomas Jefferson University.

6 Aug 2019

Alzheimer's Disease News and Research

Further Reading

Researchers identify alternate chemistry that could account for Alzheimer's pathologies

Engineers develop tissue model that mimics beta-amyloid's effects on blood-brain barrier

Alzheimer's disease attacks brain regions responsible for wakefulness

Psychiatric symptoms may indicate the beginning of Alzheimer’s disease

Excessive daytime sleeping could be an early sign of Alzheimer’s

Regular, moderate exercise appears to prevent development of physical signs of Alzheimer's

Depression symptoms together with AD pathology could trigger changes in memory and thinking

Researchers identify direct toxic action of beta-amyloid in the brain

Strong free-electron lasers can be used to break down amyloid protein aggregates

New Zealand study shows positive effect of music and dance on older adults with dementia

New initiative launched to support development and application of psychology research

APOE gene variant may be protective and prolong life, finds study

Japanese scientists develop new method to construct 3D models from 2D images

Amyloid PET scan is not an effective method for measuring severity, progression of Alzheimer's

Scientists study how mobile phones can be used to fight Alzheimer’s disease

Dietary intake of phosphatidylcholine linked to reduced dementia risk

Research findings could help identify Alzheimer's patients who will benefit from exercise

Scientists can now control neural circuits using smartphone

UNC receives $3.75 million HRSA grant to provide geriatrics training throughout North Carolina

Johns Hopkins researchers link 'stressors' in middle age to memory decline in older women

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