Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Chronic stress linked to racial discrimination may adversely impact cognition, Alzheimer's disease

Experiences of racism are associated with lower subjective cognitive function (SCF) among African-American women.

21 Jul 2020

COVID-19 vaccine displays protective traits in nonhuman primates

A replicating RNA vaccine, formulated with a lipid-based nanoparticle emulsion that goes by the acronym LION, produces antibodies against the COVID-19 coronavirus in mice and primates with a single immunization. These antibodies potently neutralize the virus.

20 Jul 2020

Involvement of nicotine receptors in COVID-19

Researchers from the University of Bristol, Oxford Brookes University and the University of California San Diego neatly demonstrated how the spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) exhibits high affinity for nicotinic acetylcholine receptors (nAChRs), with significant implications for coronavirus disease (COVID-19) pathology and infectivity. Their findings are published on the bioRxiv* preprint server.

20 Jul 2020

How immune cells switch to attack mode

Unraveling a key motif: The T lymphocytes of the immune system work to destroy infected cells or cancer cells. To do so, they have to identify the threat: Molecules perceived as foreign - so-called antigens - bind to the T-cell receptor on the T cell surface.

20 Jul 2020

Dermatopathologists influenced by malpractice and patient safety concerns when ordering multiple tests

A UCLA-led study has found that dermatopathologists, who specialize in diagnosing skin diseases at the microscopic level, are motivated both by patient safety concerns and by malpractice fears - often simultaneously - when ordering multiple tests and obtaining second opinions, with a higher proportion of these doctors reporting patient safety as a concern.

19 Jul 2020

Study reveals intricate details about the biology of huntingtin protein

A new study reveals intricate details about the biology of the huntingtin protein (HTT), which is responsible for Huntington's disease.

17 Jul 2020

Type 1 interferon deficiency as a biomarker for detecting patients at risk of severe COVID-19

Approximately 5% of people with Covid-19 progress to a severe or critical form, including the development of severe pneumonia that progresses to acute respiratory distress syndrome.

17 Jul 2020

New insight into the SARS-CoV-2 infection process

Canadian researchers from the Department of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, QC, have found that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may be using a unique method to gain entry into the cells.

16 Jul 2020

Research will help improve diagnosis of disease in newborn babies from urine samples

New research will help health-care practitioners to more accurately diagnose disease and illness in newborn babies from urine samples, according to a study by researchers at the University of Alberta and the Universidad Autónoma de Zacatecas.

16 Jul 2020

NCI funds researchers to investigate how antibody responses affect COVID-19 outcomes

A $328,000 National Cancer Institute grant will enable researchers at Dartmouth's and Dartmouth-Hitchcock's Norris Cotton Cancer Center (NCCC) to investigate one of the mechanisms that may be responsible for the body's inability to fight COVID-19.

16 Jul 2020

Yale researchers uncover potential treatment for lethal Wolfram Syndrome

Yale pharmacology professor Barbara Ehrlich and her team have uncovered a mechanism driving a rare, lethal disease called Wolfram Syndrome and also a potential treatment. Their findings appear in the July 6 edition of Proceedings of the National Academy of Sciences.

16 Jul 2020

Study finds significant variability in the accuracy of currently available COVID-19 antibody tests

A new peer-reviewed study by researchers at NSF International and Novateur Ventures finds significant variability in the accuracy of currently available COVID-19 antibody tests.

15 Jul 2020

Super-agers found to have increased resistance to tau and amyloid proteins

Super-agers, or individuals whose cognitive skills are above the norm even at an advanced age, have been found to have increased resistance to tau and amyloid proteins, according to research presented at the Society of Nuclear Medicine and Molecular Imaging 2020 Annual Meeting.

15 Jul 2020

Quest Diagnostics Health Trends study: HPV screening less likely to detect cervical cancer than cotesting

A Health Trends study from researchers at Quest Diagnostics and the University of Pittsburgh Medical Center provides new evidence that the HPV screening test is significantly less likely to detect cervical cancer and precancer than cotesting, a method which combines HPV and Pap testing using the same specimen.

15 Jul 2020

Viral load peaks in early stages of COVID-19 disease, shows study

In a retrospective study, investigators from New York University Langone Health found that the quantity of SARS-CoV-2 (viral load) collected from patients in the emergency department is significantly higher in patients with fewer or milder symptoms who did not require hospitalization--the opposite of what might be expected.

15 Jul 2020

Pathology News and Research

Further Reading

Chronic stress linked to racial discrimination may adversely impact cognition, Alzheimer's disease

COVID-19 vaccine displays protective traits in nonhuman primates

Involvement of nicotine receptors in COVID-19

How immune cells switch to attack mode

Dermatopathologists influenced by malpractice and patient safety concerns when ordering multiple tests

Study reveals intricate details about the biology of huntingtin protein

Type 1 interferon deficiency as a biomarker for detecting patients at risk of severe COVID-19

New insight into the SARS-CoV-2 infection process

Research will help improve diagnosis of disease in newborn babies from urine samples

NCI funds researchers to investigate how antibody responses affect COVID-19 outcomes

Yale researchers uncover potential treatment for lethal Wolfram Syndrome

Study finds significant variability in the accuracy of currently available COVID-19 antibody tests

Super-agers found to have increased resistance to tau and amyloid proteins

Quest Diagnostics Health Trends study: HPV screening less likely to detect cervical cancer than cotesting

Viral load peaks in early stages of COVID-19 disease, shows study

Study: Amount of SARS-Cov-2 receptor is increased in patients with pre-existing cardiac conditions

Researchers characterize how changes in glioblastoma cells influence different drug effects

UVA scientists identify oncogene responsible for deadliest brain tumor

Compound in pickled capers can directly regulate proteins required for bodily processes

Severely injured donor lungs can be successfully recovered outside the body

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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