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Angina is chest pain or discomfort that occurs when an area of your heart muscle doesn't get enough oxygen-rich blood. Angina may feel like pressure or squeezing in your chest. The pain also may occur in your shoulders, arms, neck, jaw, or back. It can feel like indigestion.

New data supports earlier use of evolocumab in high-risk diabetes

Adding the PCSK9 inhibitor evolocumab to a high-intensity, cholesterol-lowering regimen reduced the risk of a first major cardiovascular event among adults with atherosclerotic cardiovascular disease (ASCVD) or diabetes , according to a preliminary late-breaking science presentation today at the American Heart Association's Scientific Sessions 2025.

11 Nov 2025

MRI-based blood flow testing offers better answers for unexplained chest pain

Chest pain may still be angina even when coronary angiogram testing shows the main heart arteries look clear. Using stress cardiac stress MRI testing to measure blood flow around the heart appears to improve diagnosis and patient quality of life.

10 Nov 2025

Study reveals double trouble for peripheral arterial disease patients with AFib

New research from Intermountain Health in Salt Lake City finds that patients diagnosed with peripheral arterial disease (PAD) who also have atrial fibrillation (AFib) face a significantly higher risk of major adverse cardiovascular events (MACE).

10 Nov 2025

Coronary artery calcium score could help predict overall health and all-cause mortality

In a new study of more than 40,000 patients, researchers at Intermountain Health in Salt Lake City have found that patients who have no evidence of calcium in their coronary arteries are not only significantly less likely to die from heart conditions – including heart attacks and heart failure– but also are at reduced risk of death from non-cardiac medical conditions.

10 Nov 2025

Frequent exercise reshapes nerves that control the heart, research shows

Frequent exercise doesn't just strengthen the heart – it also changes the nerves that control it, according to new research which could guide more targeted and effective care for common heart problems.

23 Sep 2025

Scientists use blood chemistry to predict disease years before it strikes

Researchers built the largest plasma metabolome-phenome atlas using 274,241 UK Biobank participants, linking over 73,000 metabolite-trait and 52,000 metabolite-disease associations. The study shows metabolic risk scores can predict diseases years before diagnosis, with strong accuracy for diabetes and kidney complications.

22 Sep 2025

Research reveals widespread cardiac harm from COVID, offers solutions

Millions of people around the world are suffering with the serious cardiovascular effects of Covid infection and long Covid. A lack of clear guidance on how to reduce this suffering and prevent further harm means that patients are not receiving the care they need, and some are turning to unproven or unsafe treatments.

18 Sep 2025

Covid vaccinations remain vital to protect global heart health

Regular Covid vaccinations should continue worldwide to reduce cardiac risks associated with the virus - according to new research from the University of East Anglia.

17 Sep 2025

Trial compares the use of blood thinners after stenting in patients with acute coronary syndromes

Noninferiority was not demonstrated for death and ischemic events between P2Y12 inhibitor monotherapy and dual antiplatelet therapy (DAPT) given for 12 months after stenting in patients with acute coronary syndromes (ACS), according to late-breaking research presented in a Hot Line session today at ESC Congress 2025 and simultaneously published in New England Journal of Medicine.

3 Sep 2025

Dual antiplatelet therapy shows no benefit over aspirin after CABG in patients with acute coronary syndrome

Dual antiplatelet therapy (DAPT) was not more effective than aspirin alone for the prevention of major adverse cardiovascular events and increased major bleeding in patients with acute coronary syndrome (ACS) who underwent coronary artery bypass grafting (CABG), according to late-breaking research presented in a Hot Line session today at ESC Congress 20251 and simultaneously published in New England Journal of Medicine.

3 Sep 2025

Dual antiplatelet therapy after heart bypass surgery offers no added benefit over aspirin alone

Dual antiplatelet therapy after heart bypass surgery is not more effective than aspirin alone - and it increases the risk of excessive bleeding. This has now been shown in a study of 2,201 patients at 22 Nordic heart surgery units.

1 Sep 2025

Research finds no added benefit from routine CT imaging after left main coronary intervention

Routine coronary computed tomography (CCT)-based follow-up after percutaneous coronary intervention (PCI) of the left main coronary artery did not reduce death, myocardial infarction (MI), unstable angina or stent thrombosis compared with symptom-based follow-up, according to late-breaking research presented in a Hot Line session today at ESC Congress 2025.

1 Sep 2025

Ivabradine fails to prevent myocardial injury after noncardiac surgery in large clinical trial

Ivabradine did not reduce the occurrence of myocardial injury after noncardiac surgery (MINS), according to late-breaking research presented in a Hot Line session today at ESC Congress 2025.

1 Sep 2025

Chinese scientists develop highly efficient process for beta-blocker production

Chinese scientists have developed a breakthrough process that significantly improves the efficiency and environmental friendliness of beta-blocker production-with a focus on the widely used compound propranolol, which plays a vital role in managing cardiovascular conditions such as hypertension, arrhythmia, and angina.

20 Jun 2025

Sedentary behavior increases risk of death or cardiac events post-heart attack

People who sit or remain sedentary for more than 14 hours a day, on average, may have a higher risk of a cardiovascular event or death in the year after treatment at a hospital for symptoms of a heart attack such as chest pain, according to new research published today in the American Heart Association's peer-reviewed scientific journal Circulation: Cardiovascular Quality and Outcomes.

19 May 2025

FAME-3 study reveals similar outcomes for CABG and PCI in severe triple-vessel heart disease

In sharp contrast to earlier studies, patients with severe triple-vessel heart disease fared equally well whether they underwent open-heart bypass surgery (CABG) or a less invasive procedure called PCI (percutaneous coronary intervention) at five years of follow-up, according to research presented at the American College of Cardiology's Annual Scientific Session.

31 Mar 2025

WARRIOR trial finds no impact of intensive therapy on heart events in women

An intensive three-drug regimen of heart medications did not significantly impact the rate of serious cardiovascular events at five years in women who experienced signs and symptoms of ischemia, or insufficient blood flow to the heart muscle, but had no blockages in their heart's arteries, according to research presented at the American College of Cardiology's Annual Scientific Session.

29 Mar 2025

Lifestyle and health factors have greater impact on cardiovascular risk in women than men

Lifestyle and health factors that are linked with heart disease appear to have a greater impact on cardiovascular risk in women than men, according to a study being presented at the American College of Cardiology's Annual Scientific Session (ACC.25).

18 Mar 2025

Childhood abuse doubles adult risk of chronic health conditions

A new study published this week in Child Maltreatment found that in comparison to those who had not been abused in childhood, adults who had experienced both childhood physical and sexual abuse had approximately double the odds of physical and mental health conditions, including angina, arthritis, asthma, COPD, heart attack, depression, and disability -- even after considering respondents' age, race, income, and health behaviors, as well as obesity.

11 Mar 2025

Study reveals growing divide in cardiovascular health in the U.S.

A study published March 6 in The Lancet Regional Health - Americas highlights a growing divide in cardiovascular health in the U.S., showing that wealth and education play a significant role in heart disease risk.

8 Mar 2025

Angina News and Research

Further Reading

New data supports earlier use of evolocumab in high-risk diabetes

MRI-based blood flow testing offers better answers for unexplained chest pain

Study reveals double trouble for peripheral arterial disease patients with AFib

Coronary artery calcium score could help predict overall health and all-cause mortality

Frequent exercise reshapes nerves that control the heart, research shows

Scientists use blood chemistry to predict disease years before it strikes

Research reveals widespread cardiac harm from COVID, offers solutions

Covid vaccinations remain vital to protect global heart health

Trial compares the use of blood thinners after stenting in patients with acute coronary syndromes

Dual antiplatelet therapy shows no benefit over aspirin after CABG in patients with acute coronary syndrome

Dual antiplatelet therapy after heart bypass surgery offers no added benefit over aspirin alone

Research finds no added benefit from routine CT imaging after left main coronary intervention

Ivabradine fails to prevent myocardial injury after noncardiac surgery in large clinical trial

Chinese scientists develop highly efficient process for beta-blocker production

Sedentary behavior increases risk of death or cardiac events post-heart attack

FAME-3 study reveals similar outcomes for CABG and PCI in severe triple-vessel heart disease

WARRIOR trial finds no impact of intensive therapy on heart events in women

Lifestyle and health factors have greater impact on cardiovascular risk in women than men

Childhood abuse doubles adult risk of chronic health conditions

Study reveals growing divide in cardiovascular health in the U.S.

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