Cholesterol News and Research

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Cholesterol is a waxy, fat-like substance made in the liver, and found in the blood and in all cells of the body. Cholesterol is important for good health and is needed for making cell walls, tissues, hormones, vitamin D, and bile acid.

Can broccoli sprouts help with insulin resistance? New review offers clues

A review published in the British Journal of Nutrition examines how carotenoids and bioactive compounds in Brassicaceae microgreens may influence obesity, insulin resistance, and type 2 diabetes through metabolic and inflammatory pathways. Small human trials involving broccoli sprouts have reported improvements in selected metabolic markers, but larger, longer-term studies are needed to establish their clinical benefits.

29 Oct 2026

Limited app use adds a twist to a nurse-led dementia risk trial

A cluster-randomized trial involving 403 Australian adults aged 45–65 found that a 12-month nurse-led behavioral intervention supported by a mobile app modestly improved estimated dementia risk scores compared with brief counseling and usual care. The study found no significant improvements in cognitive performance or other secondary outcomes, leaving its long-term effects on dementia prevention uncertain.

28 Oct 2026

CT scans linked vitamin D levels to fat within muscles after bariatric surgery

Researchers followed 113 adults for one year after bariatric surgery and found that those with higher postoperative vitamin D concentrations had less fat infiltration within certain muscles and lower visceral adiposity. They found no significant association between increases in vitamin D and changes in body composition after correction for multiple comparisons, while preoperative vitamin D levels did not independently predict postoperative body composition.

27 Oct 2026

Vitamin B5 derivative pantethine helps prevent and alleviate psoriasis symptoms in mice

Researchers in China have discovered that the vitamin B5 derivative pantethine limits the activity of immune cells that are key contributors to autoimmune diseases such as psoriasis.

27 Oct 2026

High intake of saturated fat can promote favorable changes in cardiovascular risk markers

New analyses from the Norwegian randomized controlled trial CARBFUNC show that more than doubling saturated fat intake over a two-year period can promote favorable changes in several cardiovascular risk markers, without increasing apoB, the main suspected risk factor.

27 Oct 2026

Medical societies release landmark framework redefining women's heart health

Today, the American Heart Association, American Academy of Pediatrics, American College of Obstetricians and Gynecologists and the Society for Maternal-Fetal Medicine released a landmark publication that redefines heart health in girls and women.

26 Oct 2026

New report urges unified lifecycle approach to women's heart health

A new approach to women's heart health may offer them a lifetime of opportunities. A trio of scientific papers, published today in the journal Circulation, spells out how fluctuating hormones, mental health and well-being, the heart and the brain are linked and how those connections need to be a routine part of care from a young age.

26 Oct 2026

Women and men face different heart attack risks with diabetes

Cholesterol abnormalities and high blood pressure contribute to diabetes-related heart attack risk, with significant implications for cardiovascular health.

23 Oct 2026

New clinical decision support tool aims to improve chronic kidney disease care

Investigators have developed and validated a clinical decision support tool to improve the diagnosis and treatment of chronic kidney disease (CKD) at the point of care. The research will be presented at ASN Kidney Week 2026 October 22–25.

22 Oct 2026

Scientists studied one million immune cells and found clues to future disease risk

Researchers developed a single-cell atlas of one million human neutrophils, identifying distinct immune cell populations and gene-expression patterns across tissues, infections, cancer, and other health conditions. Certain neutrophil signatures were associated with metabolic dysfunction, cancer outcomes, and mortality, while higher routine neutrophil counts, even within the normal range, were linked to an increased risk of chronic disease.

22 Oct 2026

Newer anticoagulants linked to fewer strokes and deaths after brain bleeds

For people with atrial fibrillation (AFib), an irregular heartbeat, and intracranial hemorrhage, a type of stroke also known as a brain bleed, anticoagulant use was associated with a lower risk of an ischemic stroke and death, according to a new study published October 21, 2026, in Neurology®, the official medical journal of the American Academy of Neurology.

21 Oct 2026

Why the same healthy diet may not work the same way for everyone

A review published in Nutrients proposes a seven-pillar precision nutrition framework that combines biological, behavioral, and environmental information to tailor dietary interventions throughout life. The authors identify potential benefits for cardiovascular, respiratory, blood, and sleep health, while emphasizing the need for further clinical trials to establish effective, accessible, and personalized nutritional strategies.

20 Oct 2026

Experts weigh risks of using gene therapies for common diseases

Gene therapy is no longer the future of medicine - it's reality. Treatments that replace, silence or edit genes are already changing clinical care.

20 Oct 2026

AI study of 101,000 patients links brown fat to heart and mental health

In a retrospective analysis of PET-CT records from 101,243 patients, researchers found that detectable brown fat was associated with lower prevalence of cardiometabolic and psychiatric conditions, while greater activity, particularly in the axillary region, was linked to more favourable metabolic outcomes. Medication screening identified losartan, which increased brown fat thermogenic activity in laboratory experiments and energy expenditure in mice, although its effects on human brown fat remain unproven.

15 Oct 2026

New scientific statement urges doctors to prescribe exercise for heart health

Exercise should be prescribed as a foundational component of cardiovascular disease (CVD) prevention and treatment, according to a new American College of Cardiology Scientific Statement published today in JACC, its flagship journal.

15 Oct 2026

A protective brain enzyme may counteract aging-associated cognitive decline

Cinzia Vicidomini, PhD, and Amar Sahay, PhD, of the Mass General Brigham Department of Psychiatry, the Harvard Stem Cell Institute and the Broad Institute of Harvard and MIT, are the lead and senior authors of a paper published in Nature Neuroscience, "An aging-sensitive secreted phospholipase confers neuroprotection and cognitive resilience."

15 Oct 2026

Losing weight is one thing. Keeping your muscle is another, experts say

The International Society of Sports Nutrition (ISSN) position stand concludes that sustained calorie restriction drives weight loss, while adequate protein intake and resistance training help preserve lean mass. Reviewing intermittent fasting, ketogenic diets, and other dietary approaches, the authors emphasize individualized nutrition plans, body composition, and sustainable weight management rather than rapid weight loss alone.

14 Oct 2026

From turmeric to fenugreek, scientists examine nature’s potential role in diabetes care

A narrative review examined how curcumin, honey, culinary spices, and traditional remedies may influence oxidative stress, inflammation, mitochondrial function, and insulin signaling in diabetes. Although experimental research and some clinical trials suggest potential metabolic benefits, the authors emphasize that larger, well-controlled studies are needed to establish their effectiveness and safety alongside conventional treatments.

14 Oct 2026

Beyond ‘bad’ cholesterol: new clues to the risk of heart disease

Researchers at Chalmers University of Technology, in Sweden, shed new light on the remaining risk of heart disease, even after the known risk factor of ‘bad’ cholesterol is brought down to a healthy level.

13 Oct 2026