Embryonic Stem Cells News and Research

RSS

Researchers identify hundreds of genes essential for the development of brain cells

An international research team identified hundreds of genes essential for the development of brain cells, including one gene linked to a severe neurodevelopmental disorder not previously described.

5 Jan 2026

Researchers create the most detailed 3D maps of the human genome

In a landmark effort to understand how the physical structure of our DNA influences human biology, Northwestern investigators and the 4D Nucleome Project have unveiled the most detailed maps to date of the genome's three‑dimensional organization across time and space, according to a new study published in Nature.

22 Dec 2025

Cells balance protein production and removal through passive adaptation

Every cell depends on proteins to function and stay healthy. These proteins are made inside the cell from amino acids but cannot simply accumulate inside the cell forever.

22 Dec 2025

Viral DNA elements help control early embryonic development

Transposable elements are stretches of DNA that can move around the genome. Many of these DNA sequences originate from long ago, when viruses inserted their genetic material into our ancestors' genomes during infection.

19 Dec 2025

New tear gland organoids shed light on the biology of dry eye disease

An estimated 5-15% of people have problems with dry eyes, with symptoms including eye redness, stinging, or burning sensation, and eye fatigue. Dry eye disease (DED) occurs when the eyes' tear glands produce insufficient or poor-quality tears which can be due to allergy or autoimmune disease, hormonal changes, aging, etc.

18 Dec 2025

New clinical trial offers hope for patients with advanced “dry” age-related macular degeneration

Age-related macular degeneration, the leading cause of vision loss and blindness for Americans 65 and older, is a progressive disease affecting central vision.

17 Dec 2025

Study uncovers role of mechanical forces in human gastrulation

Only two weeks after fertilization, the first sign of the formation of the 3 axes of the human body (head/tail, ventral/dorsal, and right/left) begins to appear.

22 Nov 2025

SwRI-developed single-use 3D-printed bioreactor harvests induced Pluripotent Stem Cells

Southwest Research Institute (SwRI) has demonstrated a new application for its cell-expansion bioreactor to advance tissue engineering and cell-based therapies for treatment of injuries and diseases.

12 Nov 2025

Study reveals how "P bodies" heavily influence a cell's fate

How do stem cells know what to become? Nearly three decades after scientists isolated the first human embryonic stem cells, researchers are still working hard to understand precisely how a single, undifferentiated cell can become any one of the roughly 200 cell types that make up the human body.

4 Nov 2025

New method yields up to twice as many therapeutic myogenic cells as previous protocols

If cancer is a disease of overabundance, where cells divide without restraint and tumors grow despite the body's best interests, then degenerative diseases are disorders of deprivation.

30 Oct 2025

Advancements in organoids could transform treatment of spinal cord injury and peripheral nerve injury

A recent review published in Engineering explores the construction and potential applications of spinal cord and peripheral nerve organoids for regenerative medicine in neurotrauma.

24 Oct 2025

Multidimensional regulation of stem cell fate by the cohesin complex

Conventional studies on stem cell fates are primarily focused on transcription factors, with the limited consideration for 3D genome architecture.

10 Oct 2025

New tool enables and enhances protein investigations

A new tool greatly improves scientists' ability to identify and study proteins that regulate gene activity in cells, according to research led by Weill Cornell Medicine investigators. The technology should enable and enhance investigations in both fundamental biology and disease research.

3 Oct 2025

Scientists outline how future therapies could change type 1 diabetes care

Researchers writing in The Lancet review breakthroughs in type 1 diabetes treatment, from immunotherapies that delay onset to stem-cell β-cell replacement and automated insulin delivery. They stress that equitable access, validated surrogate endpoints, and scalable technologies are crucial for lasting impact.

24 Sep 2025

LINE-1 elements found essential for early embryonic development

A new review from Genes and Diseases sheds light on the pivotal role of LINE-1 elements in preimplantation development and totipotency, revealing their essential contributions to early mammalian embryogenesis.

25 Jun 2025

Study uncovers common trigger across gene mutations that cause ALS

Using the gene scissors CRISPR and stem cells, researchers at Stockholm University and the UK Dementia Research Institute (UK DRI) at King's College London have managed to identify a common denominator for different gene mutations that all cause the neurological disease ALS.

19 May 2025

Research identifies seven genes that drive hematopoietic stem cell fate

Stem cells can produce any other cell type, it is just a matter of telling them in the right way. From a biological perspective, this means activating the proper genetic programme by pressing the right keys, this is, the right genes, at the right moment.

16 May 2025

New stem cell model replicates human amniotic sac development

Researchers at the Francis Crick Institute have developed a new stem cell model of the mature human amniotic sac, which replicates development of the tissues supporting the embryo from two to four weeks after fertilization.

15 May 2025

Stem cell therapy shows promise for treating advanced Parkinson's disease

A stem cell–based therapy initially developed at Memorial Sloan Kettering Cancer Center (MSK) may lead to a new treatment for advanced Parkinson's disease, according to results from a phase 1 clinical trial reported in Nature.

16 Apr 2025

Stanford study reveals glucose's surprising role in cell differentiation

The sugar glucose, which is the main source of energy in almost every living cell, has been revealed in a Stanford Medicine study to also be a master regulator of tissue differentiation - the process by which stem cells give rise to specialized cells that make up all the body's tissues.

25 Mar 2025