Fluorophore News and Research

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Highly effective detection of cancer biomarkers using CRISPR

Most cancer diagnostic techniques rely on uncomfortable and invasive procedures, such as biopsies, endoscopies or mammograms.

1 Feb 2023

New tool for noninvasive imaging can help illuminate hard-to-access brain structures

Talk about a bright idea: Thanks to chemists at Rice University and Stanford University, lighting up the brain is no longer just a figure of speech.

17 Jan 2023

Researchers develop a novel, improved system for identifying fluorescent agents

The nascent field of fluorescence-guided surgery (FGS) is fast growing, with potential to vastly improve the safety and efficacy of surgical procedures.

9 Jan 2023

Researchers develop a new method to map the spatial evolution of cancers

Researchers developed a genetic clone mapping workflow centered around base-specific in situ sequencing (BaSISS) technology to derive quantitative maps of multiple genetic clones of cancer cells.

11 Nov 2022

Low-cost imaging system uses fluorescent molecules to determine the depth of tumor cells

Researchers have developed a low-cost, simple imaging system that uses tumor-targeting fluorescent molecules to determine the depth of tumor cells in the body.

6 Oct 2022

Study identifies two potential serological biomarkers of monkeypox infection

In a new study, researchers pursued two monkeypox virus (MPXV) immune targets, A35R and H3L, that could be deployed in a serological assay to identify recent MPXV cases.

29 Aug 2022

DNA origami as an alternative platform to display the RBD of SARS-CoV-2

Researchers demonstrated DNA origami as a potential platform to display the SARS-CoV-2 receptor-binding domain.

23 Aug 2022

What risk factors are associated with post-acute sequelae of SARS-CoV-2?

Researchers explored the risk factors correlated with post-acute sequelae of SARS-CoV-2.

23 Aug 2022

Discovery of multiple new SARS-CoV-2 MPro inhibitors

In a recent study posted to the bioRxiv* preprint server, researchers performed an extensive library docking for new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease (Mpro) covalent and non-covalent inhibitors.

8 Jul 2022

Scientists create new fluorophores that could help fight cancer

Scientists from the Ural Federal University and the Ural Branch of the Russian Academy of Sciences have created new fluorescent chemical compounds (fluorophores) for photodynamic therapy of cancerous tumors, the latest method of treating cancer.

27 Jun 2022

New sensor accurately determines the human saliva pH

Chemists at the Ural Federal University have created a sensor for determining the human saliva pH. This is a fluorophore with strong and stable emission, which picks up the smallest fluctuations in the pH(tenths) in biological fluids.

16 Jun 2022

CRISPR-based diagnostics for SARS-CoV-2 detection

In a recent study posted to the Journal of Biochemical and Molecular Toxicology, researchers reviewed clustered regularly interspaced short palindromic repeats (CRISPR)-based diagnostics for detecting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

6 Jun 2022

Scientists develop new technology to solve common surgical problem of nerve damage

A research collaboration including scientists from Oregon State University has developed a new technology to help surgeons know where a patient's nerves are, lessening the chance of nerve damage.

1 Jun 2022

Nanotechnology enhanced DNA-chip for SARS-CoV-2 detection with variant differentiation

Researchers differentiated between SARS-CoV-2 variants using nanotechnology.

26 May 2022

Researchers combine two emerging imaging technologies to better view biomolecules

A research team from Carnegie Mellon University and Columbia have combined two emerging imaging technologies to better view a wide range of biomolecules, including proteins, lipids and DNA, at the nanoscale.

19 May 2022

Exploring Populations of B and T Cells in Lymph Nodes of Patients Diagnosed with COVID-19 via Microscopy and Image Analysis

My work is focused on looking at the dynamics of B/T cell populations within lymph nodes from patients that had recovered from COVID-19. My role in this research was developing and implementing microscopy image analysis techniques using methods and instrumentation in part supplied by TissueGnostics.

From TissueGnostics 26 Apr 2022

Researchers create method to track SARS-CoV-2 RBD binding in vivo

Researchers developed a method for tracking the binding of the receptor-binding domain of SARS-CoV-2 in vivo using genetically engineered extracellular vesicles that can migrate to ACE2 expressing cells.

30 Mar 2022

Revolutionizing the fluorescence microscopy landscape with the all-in-one Microhub, Mica

In this interview, News-Medical talks to James O'Brien, Vice President at Leica Microsystems, about their latest development, the Mica microhub, and how this could revolutionize and advance the field of fluorescence microscopy.

From Leica Microsystems GmbH 30 Mar 2022

Cell surface expression of SARS-CoV-2 nucleocapsid protein and its role in immunity

Researchers demonstrated the unexpected roles of nucleocapsid protein in innate and adaptive immunity to SARS-CoV-2.

15 Dec 2021

CRISPR-Cas enzyme-based diagnostics to detect SARS-CoV-2 infection

A recent review in the journal Life provided a detailed description of CRISPR-Cas-based diagnostic techniques to identify severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, but also emphasized the potential use of this technology towards developing effective molecular diagnostic platforms for any future pandemic.

13 Dec 2021