Head and Neck Cancer News and Research

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Head and Neck Cancer is cancer that arises in the head or neck region (in the nasal cavity, sinuses, lips, mouth, salivary glands, throat, or larynx [voice box]).

Genetic ancestry influences tumor biology and survival in head and neck cancers

Genetic ancestry plays a key role in determining the behavior of head and neck tumors and may help explain why African-American patients survive for half as long as their counterparts of European ancestry, according to a new review study led by researchers from the University of Maryland School of Medicine's (UMSOM) Institute for Genome Sciences (IGS) and the University of Maryland Greenebaum Comprehensive Cancer Center (UMGCCC).

31 Jan 2026

Clinical trial aims to improve survival for patients with recurrent head and neck cancer

A newly approved National Cancer Institute-funded clinical trial aims to improve survival for head and neck cancer patients whose disease returns after radiation therapy – a setback that affects up to 40% of patients and is often associated with poor outcomes.

27 Jan 2026

Analysis reveals why head and neck cancer clinical trials end early

Head and neck cancer trials are frequently derailed before they can deliver answers. A new analysis suggests that the most common reasons are sponsor decisions related to safety or effectiveness and poor patient recruitment.

12 Jan 2026

Sugarcane protein mouthwash helps protect oral health during head and neck cancer treatment

An artificial saliva in the form of a mouthwash, produced with the CANECPI-5 protein extracted from sugarcane and modified in a laboratory, can aid in treating teeth in patients with head and neck cancer. In these cases, radiotherapy very close to the mouth can destroy salivary glands and compromise saliva production, which is essential for controlling bacteria and disease.

7 Jan 2026

BATF2: A novel tumor suppressor silenced by glutamine in head and neck cancer

A novel tumor suppressor, BATF2, can be silenced by factors in the tumor microenvironment, leading to a reduced immune response in five preclinical models of head and neck cancer, according to researchers from The University of Texas MD Anderson Cancer Center.

7 Jan 2026

Elevated bacteria levels in tumors weaken immune response, studies show

Cleveland Clinic researchers have discovered that bacteria inside cancerous tumors may be key to understanding why immunotherapy works for some patients but not others.

2 Jan 2026

Artificial intelligence improves risk stratification in oropharyngeal cancer

A team led by investigators at Mass General Brigham and Dana-Farber Cancer Institute has developed and validated an artificial intelligence (AI)–based noninvasive tool that can predict the likelihood that a patient's oropharyngeal cancer-a type of head and neck cancer that develops in the throat-will spread, thereby signaling which patients should receive aggressive treatment.

23 Dec 2025

Study links low physical activity to higher lymphedema risk after cancer treatment

Lymphedema after head and neck cancer is considerably more common than previously assumed and can persist long after cancer treatment has finished.

17 Dec 2025

Proton therapy improves survival in oropharyngeal cancer patients

A new study published today in The Lancet showed a significant survival benefit for patients with oropharyngeal cancers who were treated with proton therapy (IMPT) compared to those treated with traditional radiation therapy (IMRT).

11 Dec 2025

Cancer stole her voice. She used AI, curse words, and kids’ books to get it back.

When doctors told her they had to remove her tongue and voice box to save her life from the cancer that had invaded her mouth, Sonya Sotinsky sat down with a microphone to record herself saying the things she would never again be able to say.

21 Nov 2025

Researchers achieve long-term remission with novel T cell therapies for HPV-related cancers

Researchers from Rutgers Cancer Institute, New Jersey's only National Cancer Institute (NCI) - designated Comprehensive Cancer Center, and RWJBarnabas Health, along with colleagues from the National Cancer Institute, a center of the National Institutes of Health, announced findings from two HPV-related studies that highlight the potential of novel T cell therapies to achieve long-lasting remission and complete tumor regression in patients with advanced epithelial cancers.

10 Nov 2025

New NIH grants fuel research in oral cancer treatment and pain relief

Researchers at the School of Dentistry at UT Health San Antonio, the academic health center of The University of Texas at San Antonio, have been awarded three multi-year grants totaling $6 million from the National Institutes of Health to address treatment and pain management for oral cancer.

7 Nov 2025

Undergraduate researcher uncovers molecular secrets of HPV’s cancer-causing mechanisms

When Sean Fletcher walked into Sam Biswas' Medical and Molecular Sciences (MMSC) lab at the University of Delaware College of Health Sciences during the summer of his first year, he had no research or laboratory experience.

31 Oct 2025

GLP-1 receptor agonists linked to altered patterns on FDG PET-CT scans

The growing use of GLP-1 receptor agonists may affect the interpretation of oncological FDG PET-CT scans, new research presented today at the 38th Annual Congress of the European Association of Nuclear Medicine (EANM'25) has revealed.

7 Oct 2025

Proton therapy and IMRT show similar outcomes in head and neck cancer trial

A new phase III clinical trial finds that intensity-modulated radiation therapy (IMRT) and proton beam therapy resulted in similar quality-of-life outcomes and low rates of side effects for people with locally advanced oropharyngeal cancer.

29 Sep 2025

UCLA presents advances in radiation therapy at ASTRO 2025

Physicians and scientists from the UCLA Health Jonsson Comprehensive Cancer Center will share the latest research and clinical trial results at the 2025 American Society for Radiation Oncology (ASTRO) Annual Meeting, including studies on targeted radioactive therapy for recurrent prostate cancer, new approaches to stereotactic body radiation for prostate and head and neck cancers, advances in MRI- and 5DCT-guided imaging for more precise treatments, and innovations in patient-focused cancer education.

26 Sep 2025

Head and Neck Cancer News and Research

Genetic ancestry influences tumor biology and survival in head and neck cancers

Clinical trial aims to improve survival for patients with recurrent head and neck cancer

Analysis reveals why head and neck cancer clinical trials end early

Sugarcane protein mouthwash helps protect oral health during head and neck cancer treatment

BATF2: A novel tumor suppressor silenced by glutamine in head and neck cancer

Elevated bacteria levels in tumors weaken immune response, studies show

Artificial intelligence improves risk stratification in oropharyngeal cancer

Study links low physical activity to higher lymphedema risk after cancer treatment

Proton therapy improves survival in oropharyngeal cancer patients

Cancer stole her voice. She used AI, curse words, and kids’ books to get it back.

Researchers achieve long-term remission with novel T cell therapies for HPV-related cancers

New NIH grants fuel research in oral cancer treatment and pain relief

Undergraduate researcher uncovers molecular secrets of HPV’s cancer-causing mechanisms

GLP-1 receptor agonists linked to altered patterns on FDG PET-CT scans

Proton therapy and IMRT show similar outcomes in head and neck cancer trial

UCLA presents advances in radiation therapy at ASTRO 2025

Genetic testing guides personalized radiation patients with HPV-positive throat cancer

BioDlink Commends Junshi Biosciences as its Bispecific ADC Candidate JS212 Receives IND Approval

New technique used to conduct real-time measurement of boron in live tumor cells

HPV-DeepSeek shows promise for early detection of head and neck cancer

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