Herpes Simplex Virus News and Research

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Study uncovers how HSV-1 disables the brain's antiviral defense

Infections caused by herpes simplex virus type 1 (HSV-1) can lead to HSV-1 encephalitis-a rare but deadly condition that inflames the brain.

3 Jun 2025

Herpes virus infection linked to higher Alzheimer’s risk, study shows antiherpetic drugs may help

A large US case-control study found that people diagnosed with herpes simplex virus type 1 (HSV-1) had a higher risk of developing Alzheimer’s disease. Use of antiherpetic medications was associated with a reduced risk of Alzheimer’s in those with HSV-1.

21 May 2025

New drug candidate disrupts the link between herpes virus and Alzheimer’s disease

Studies suggesting that certain viral infections may influence the onset of Alzheimer's diseases are gaining attention. In this context, a domestic research team has succeeded in breaking the link between viral infection and Alzheimer's disease using a new treatment candidate.

16 May 2025

HIV uses circular RNAs to evade immunity and boost replication

In a groundbreaking discovery, researchers from Florida Atlantic University's Charles E. Schmidt College of Medicine have identified a never-before-seen mechanism that enables the human immunodeficiency type 1 virus (HIV-1) to evade the body's natural defenses and use it to support its survival and replication.

13 May 2025

New approach to combat influenza and herpes with bean-based gum

In today's interconnected world, infectious diseases pose an escalating threat, as demonstrated by the coronavirus pandemic and outbreaks of H1N1, SARS, Ebola, Zika, and H5N1 (bird flu) viruses-all of which have had significant global health and economic impacts.

4 Apr 2025

Herpes infection through the nose can lead to anxiety, motor impairment and cognitive deficits

Herpes simplex virus-1 (HSV-1) is commonly known for causing blisters and sores. But in some cases, the virus can migrate to the eye or nervous system, causing severe, chronic symptoms.

10 Mar 2025

New target identified for preventing cold sores and genital herpes

Scientists have a new target to prevent cold sores after University of Virginia School of Medicine researchers discovered an unexpected way the herpes virus re-activates in the body.

28 Feb 2025

Study highlights increase in VZV-induced CNS infections and dementia risk

Researchers from Fujita Health University, Japan, observed a rise in adult central nervous system (CNS) infections, primarily aseptic meningitis caused by the varicella zoster virus (VZV), post-2019. The researchers highlighted the potential of zoster vaccination to reduce CNS infections.

27 Feb 2025

Study shows how herpes viruses contribute to Alzheimer's disease in aging brains

Researchers from Cleveland Clinic's Genome Center outlined the pathway human herpes simplex virus-1 (HSV1) can use to contribute to Alzheimer's disease in aging brains.

24 Feb 2025

Infant exposure to herpes virus may cause memory problems later in life

Very early exposure to even a very small dose of herpes simplex virus (HSV) in infant mice can lead to cognitive decline later in life, according to findings from a new Dartmouth-led study, in collaboration with Harvard Medical School and published in the journal PLoS Pathogens.

19 Feb 2025

Cancer-fighting virus T-VEC helps shrink tough-to-treat skin tumors

Talimogene laherparepvec (T-VEC) demonstrates efficacy in cutaneous BCC, enhancing resectability and altering immune cell composition with low adverse events.

30 Jan 2025

New therapy shows promise in treating basal cell carcinoma

Basal cell carcinomas, the most common form of skin cancer, occur in chronically sun-exposed areas such as the face.

27 Jan 2025

Concussions may trigger Alzheimer's symptoms through latent viruses

Concussions and repetitive head trauma in sports like football and boxing, once accepted as an unpleasant consequence of intense athletic competition, are now recognized as serious health threats.

7 Jan 2025

Study reveals surprising connection between herpes and Alzheimer's

University of Pittsburgh researchers uncovered a surprising link between Alzheimer's disease and herpes simplex virus-1 (HSV-1), suggesting that viral infections may play a role in the disease. The study results are published today in Cell Reports.

2 Jan 2025

Herpes infections soar globally as new study reveals massive disease burden

Global estimates of HSV-1 and HSV-2 reveal a staggering disease burden, with 42.4 million new genital herpes cases and 8.8 billion GUD person-days in 2020, underscoring the urgent need for improved prevention strategies.

12 Dec 2024

Herpes infections affect 846 million people worldwide

Around 846 million people aged between 15 and 49 are living with genital herpes infections – more than 1 in 5 of this age-group globally – according to new estimates released today.

11 Dec 2024

New biosensor technology could revolutionize mpox diagnosis

A new variant of human mpox has claimed the lives of approximately 5% of people with reported infections in the Democratic Republic of the Congo since 2023, many of them children. Since then, it has spread to several other countries.

14 Nov 2024

A review of clinical features, diagnosis, and management of Mpox

A comprehensive review in JAMA outlines monkeypox's clinical presentation and management, stressing the need for increased surveillance and vaccination efforts.

17 Oct 2024

New insights into pain mechanisms related to viral infections

An article published in the journal Brain, Behavior, and Immunity reports the findings of a study by researchers based in Brazil, the United States and South Korea who set out to understand how viral infections cause pain and to contribute to the search for novel ways of relieving it.

15 Oct 2024

Study uncovers mechanism of MX protein in fighting HIV-1 and herpes simplex virus

A group of researchers led by Xavier Saelens and Sven Eyckerman at the VIB-UGent Center for Medical Biotechnology discovered how a protein linked to the human immune system wards off HIV-1 and herpes simplex virus-1 by assembling structures in the cell that lure in these viruses and then trap them or even take them apart.

9 Oct 2024