High Throughput Sequencing News and Research

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Understanding viral composition in marine species from the South China Sea

Announcing a new article publication for Zoonoses journal. This study investigates the viral diversity associated with marine organisms in the South China Sea, to improve understanding of the region's viral ecosystems.

14 Dec 2024

TCR sequencing sheds light on tumor immune interactions in hepatocellular carcinoma

Hepatocellular carcinoma (HCC) stands as the dominant form of liver cancer, ranking as the fourth leading cause of cancer-related deaths globally.

11 Dec 2024

Arthritis-style immunotherapy shows promise for heart failure

A study uncovers IL-1β signaling in cardiac fibrosis, highlighting distinct fibroblast populations and promising immunotherapy strategies for heart failure.

24 Oct 2024

How your baby’s birth and environment can shape lifelong gut health

Early life factors, like birth mode and green environments, shape infant gut microbiota, with outdoor time becoming crucial in late infancy. Residential greenery impacts diversity only during early infancy.

24 Oct 2024

Scientists identify gut microbial signatures that distinguish diseases and predict health states

Study reveals significant gut microbial differences across diseases in the Chinese population, identifying universal microbial signatures that could predict disease states with high accuracy.

2 Oct 2024

Study reveals how sex hormones regulate immune system functions

Findings indicate that testosterone therapy in trans men alters immune system responses, suggesting implications for disease susceptibility and treatment.

6 Sep 2024

NIH funds study on complex evolutionary adaptation in human DNA

Natural selection is an important evolutionary force that enables humans to adapt to new environments and fight disease-causing pathogens.

3 Sep 2024

Quantum leap in single cell genomics: Scale Bio launches groundbreaking ‘100 Million Cell Challenge’ in collaboration with Ultima Genomics and NVIDIA

Scale Biosciences (Scale Bio), a leader in innovative and scalable single cell analysis solutions, today announced the launch of the “100 Million Cell Challenge,” a global initiative aimed at pushing the boundaries of single-cell genomics research.

16 Aug 2024

DeepPBS: A geometric AI model for accurate prediction of protein-DNA binding specificity

A new artificial intelligence model developed by USC researchers and published in Nature Methods can predict how different proteins may bind to DNA with accuracy across different types of protein, a technological advance that promises to reduce the time required to develop new drugs and other medical treatments.

9 Aug 2024

New combined cell therapy for kidney transplants can help reduce donor-specific immune response

A new combined cell therapy for kidney transplants can help to reduce the donor-specific reaction against the transplanted organ without the need for maintenance triple immunosuppression.

22 Jul 2024

Elite Controllers: Do their genomes hold the key to curing HIV?

Although South Africa has the largest number of people living with HIV worldwide, strides have been made in controlling the epidemic, especially in the reduction of HIV incidence, testing, and treatment. Equipped with MGI’s advanced sequencing tools and technologies, researchers from the South African Medical Research Council (SAMRC) and University of KwaZulu-Natal (UKZN) are inching closer to finding the answer to the natural control of HIV infection, leading to improved health outcomes and quality of life amongst South Africans.

From MGI 19 Jul 2024

One-time prime editing targets common genetic cause of cystic fibrosis

Researchers optimized prime editing for the efficient correction of the cystic fibrosis transmembrane conductance regulator F508del mutation in human airway epithelial cells, achieving high correction efficiencies and functional restoration with minimal off-target effects.

15 Jul 2024

MGI Tech launches whole workflow solution for agricultural large-scale low-pass whole genome sequencing at PAG Asia 2024

MGI Tech Co., Ltd. (“MGI”), a company committed to building core tools and technologies that drive innovation in life science, today announced a highly efficient whole workflow solution for agricultural large-scale Low-pass whole genome sequencing (Low-pass WGS) based on its proprietary DNBSEQTM platforms during this year’s International Plant and Animal Genome Conference Asia (PAG Asia 2024), taking place on June 5-7 in Shenzhen, China.

From MGI 7 Jun 2024

Using microbiota analysis for health and disease management

The human body harbors approximately 30 trillion microbes, known collectively as the microbiota.

28 Mar 2024

Nucleus Genomics ushers in a new era of personalized medicine to the public

Nucleus Genomics, the next-generation genetic testing and analysis company, today announced the launch of its DNA analysis product to bring the benefits of personalized medicine to everyone.

25 Mar 2024

MGI enters strategic partnership with Prepaire Labs to advance drug discovery and precision medicine

MGI, a company committed to building core tools and technology to lead life science, today announced its collaboration with Prepaire Labs at MEDLAB Middle East 2024 to further empower precision medicine.

From MGI 6 Mar 2024

MGI Tech and Eurofins genomics partner to elevate precision health with revolutionary DNBSEQ-T20×2 Sequencer and Related Technologies

MGI Tech, a company committed to building core tools and technology to lead life science, today proudly announced a milestone collaboration with Eurofins Genomics Europe Genotyping A/S (“Eurofins Genomics”), which has placed a corporate order of the revolutionary DNBSEQ-T20×2 (“T20”) ultra-high throughput sequencer, along with the genomics data center ZTRON Appliance and a range of MGI’s state-of-the-art laboratory automation products and systems.

From MGI 6 Mar 2024

DNA aptamer-based sensors can accurately detect trace amounts of fentanyl, heroin, and cocaine

Researchers from North Carolina State University have developed a new generation of high-performance DNA aptamers and highly accurate drug sensors for cocaine and other opioids.

5 Mar 2024

Ultima announces UG 100™ and reveals disruptive cost and accuracy profile to enable the era of the $100 genome and beyond

Today, the Company is also introducing ppmSeqTM, a disruptive new mode for extreme raw read accuracy in calling single nucleotide variants (SNVs). ppmSeqTM is a new proprietary feature enabled by Ultima’s unique approach that dramatically improves the raw read accuracy of calling SNVs by removing sample errors introduced upstream of the sequencing workflow.

From Ultima Genomics, Inc. 26 Feb 2024

Monash-led study unveils potential long-term treatment for lupus

Researchers assessed Smith (Sm)-specific regulatory T cells (Tregs) efficacy in halting lupus nephritis (LN) by engineering and testing epitope-targeted Tregs for systemic lupus erythematosus (SLE) treatment.

8 Feb 2024