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Transcutaneous vagal nerve stimulation shows promise for gastrointestinal disorders

Imbalanced autonomic function, characterized by reduced vagal activity and sympathetic dominance, is increasingly recognized in various gastrointestinal (GI) disorders.

27 Aug 2025

Shame linked to lower quality of life in people with gut disorders

Feelings of shame are linked to reduced quality of life - as shown by the first study to measure shame as a factor influencing the connection between chronic gastrointestinal disorders and mental health.

25 Aug 2025

Hemoglobin emerges as a natural antioxidant defense in the brain

Did you know the same protein that gives blood its red color and carries oxygen throughout the body is also present inside brain cells? Hemoglobin, long celebrated for ferrying oxygen in red blood cells, has now been revealed to play an overlooked - and potentially game-changing - antioxidant role in the brain.

22 Aug 2025

Low FODMAP diet increases GLP-1 and relieves IBS symptoms

This study reveals that a low FODMAP diet alleviates IBS symptoms and increases GLP-1 levels, suggesting new avenues for dietary interventions in gut health.

20 Aug 2025

Survey reveals persistent challenges of IBS on daily life and productivity

Despite social media helping to increase awareness of irritable bowel syndrome (IBS) among the public (81% of health care providers agree) and advancements in treatment over the past decade, IBS symptoms continue to significantly impact patients' daily lives and productivity, according to a new survey released by the American Gastroenterological Association (AGA), in partnership with The Harris Poll, a Stagwell (STGW) agency.

7 Aug 2025

Low FODMAP diet found to repair leaky gut in IBS-D patients

In a study, patients with irritable bowel syndrome with diarrhea, or IBS-D, who went on a low FODMAP diet saw an improvement of colonic barrier dysfunction, commonly known as "leaky gut."

30 Jul 2025

Study confirms post-pandemic rise in disorders of gut-brain interaction

A new international study confirmed a significant post-pandemic rise in disorders of gut-brain interaction, including irritable bowel syndrome (IBS) and functional dyspepsia, according to the paper published in Clinical Gastroenterology and Hepatology.

30 Jul 2025

Gut hormone INSL5 linked to chronic diarrhea in patients with bile acid malabsorption

High levels of a hormone found in cells in the gut could underlie many cases of chronic diarrhea and help explain up to 40% of cases of patients with irritable bowel syndrome with diarrhea, according to a new study led by scientists at the University of Cambridge.

29 Jul 2025

Scientists uncover new brain mechanism driving PTSD and potential counter-drug

Did you know that patients with post traumatic stress disorder (PTSD) often struggle to forget traumatic memories, even long after the danger has passed? This failure to extinguish fear memories has long puzzled scientists and posed a major hurdle for treatment, especially since current medications targeting serotonin receptors offer limited relief for only a subset of patients.

29 Jul 2025

Gluten may not be the culprit for many people with irritable bowel syndrome

A new study from McMaster University researchers has found that many people with irritable bowel syndrome (IBS) who believe they are sensitive to gluten or wheat may not actually react to these ingredients.

22 Jul 2025

Viome and Scripps Research join forces to develop at-home RNA test for colon cancer prevention

Viome Life Sciences, the leader in AI-powered, RNA-based diagnostics and precision nutrition and Scripps Research, the leader in accelerating the impact of fundamental research on human health, today announced a strategic partnership to develop and clinically validate the first at-home RNA test designed to detect precancerous colon polyps, enabling early prevention of colorectal cancer.

14 Jul 2025

Study finds significant uptick in chronic digestive disorders during COVID-19 pandemic

A study led by Cedars-Sinai investigators uncovered a significant uptick in chronic digestive disorders, like irritable bowel syndrome, during the COVID-19 pandemic.

3 Jul 2025

Low FODMAP diet shown to improve gastrointestinal symptoms in women with endometriosis

A low FODMAP diet developed by Monash University researchers for irritable bowel syndrome (IBS) has been shown to improve gastrointestinal symptoms in women with endometriosis.

23 Jun 2025

Estrogen-responsive cells found to heighten gut pain in females

Researchers uncovered how estrogen heightens gut sensitivity in females by activating PYY-secreting L-cells, which stimulate serotonin release from EC cells. This paracrine circuit intensifies pain signaling and may explain the sex bias in conditions like IBS.

16 Jun 2025

New open access tool could accelerate drug discovery

Scientists at Northwestern University have developed the largest open-access resource of its kind to help researchers shave off months of early-stage drug development time by allowing them to better understand diseases and find potential treatments.

12 Jun 2025

New non-invasive method boosts the brain's natural waste drainage system

Scientists at the Institute for Basic Science (IBS) have uncovered a non-invasive method to boost the brain's natural waste drainage system-a discovery that could open new avenues for tackling age-related neurological disorders.

4 Jun 2025

ADHD linked to higher risk of irritable bowel syndrome, global study reveals

A global meta-analysis found that people with ADHD are significantly more likely to have irritable bowel syndrome (IBS), while the overall risk for other intestinal disorders is not increased. The findings highlight the importance of gut-brain interactions in ADHD and call for further research on microbiome-based therapies.

3 Jun 2025

Transforming IBS treatment through psychedelic medicine

In a comprehensive Genomic Press Interview published today, Dr. Erin E. Mauney reveals how her pioneering research brings psychedelic medicine into gastroenterology for the first time, potentially transforming treatment for millions suffering from intractable irritable bowel syndrome (IBS).

3 Jun 2025

Breakthrough bat organoid platform sheds light on behavior of zoonotic viruses

Did you know that more than 75% of new infectious diseases affecting humans originally come from animals? Bats, in particular, are natural hosts to some of the world's most dangerous viruses, including those responsible for COVID-19 (SARS-CoV-2), MERS-CoV, influenza A, and hantavirus outbreaks.

15 May 2025

Can diet ease IBS? A low-FODMAP plan cut symptoms but raised nutrient concerns

A 10-week low-FODMAP diet significantly reduced symptom severity in Saudi adults with IBS, with most shifting from severe to moderate symptoms. However, the restrictive diet also led to declines in several essential nutrients, highlighting the need for professional guidance.

14 May 2025