Lyophilization News and Research

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Freeze-drying, also referred to as lyophilization, is a process that involves freezing a substance at very low temperatures and then extracting liquid via sublimation, converting water from a solid to gaseous state.

New production method developed to freeze-dry COVID-19 vaccines

UMass Lowell scientists are developing a production method to freeze-dry COVID-19 vaccines activated by messenger-RNA so they can be transported and stored at room temperature.

21 Jan 2022

Cas13 shines a light on SARS-CoV-2 variants

Now, a new study published on the medRxiv* preprint server describes and benchmarks SHINEv2, a Cas13-based nucleic acid diagnostic for SARS-CoV-2 detection. SHINEv2 combines temperature sample processing and lyophilized reagents to simplify the test procedure and assay distribution immensely.

4 Nov 2021

Study shows efficacy of gamma irradiation of SARS-CoV-2 vaccine candidate in mouse model

A new study reports a more rapid method of viral inactivation in an effort to increase the appeal of inactivated viral vaccines against the COVID-19 pandemic.

10 Aug 2021

COVID-19 PCR tests can withstand freeze-drying process

In fighting the COVID-19 pandemic, it's not just the vaccines that require complicated cold supply chains and refrigerated storage. Polymerase chain reaction (PCR) tests -- often considered the "gold standard" of testing -- also have enzymes and reagents that need to be frozen.

14 Jun 2021

Protein-based vaccines against SARS-CoV-2 may provide advantages over mRNA-based vaccines

Researchers in the UK have developed a protein-based subunit vaccine directed against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that could serve as an alternative to the mRNA-based vaccines currently approved for protecting against coronavirus disease 2019 (COVID-19).

20 May 2021

Researchers develop thermostable RNA vaccine delivery platform

A new study describes the production of a new RNA vaccine delivery system that promises greater ease of storage and distribution. This could help boost vaccination rates in regions without adequate infrastructure for low-temperature storage.

4 Feb 2021

Smart Evaporator Assists Medicinal Chemistry

BioChromato Inc. has published an interview with the Department of Medicinal Chemistry and Molecular Pharmacology at Purdue University (Indiana, USA) that explains how the Smart Evaporator C1 has assisted them in isolating and purifying novel compounds from DMSO solutions for potential pharmaceutical use.

From BioChromato Inc. 3 Dec 2020

SGD Pharma extends industry-leading Ready-to-Use molded glass vial range with introduction of EasyLyo and ISO20mm 50ml sizes in tray

SGD Pharma extends leading glass vial range with new sizes

From SGD Pharma 2 Oct 2020

A biomaterial vaccine for SARS-CoV-2 - quick and scalable

A recent 'tour-de-force' research endeavor, led by scientists from Harvard University, explored the propensity of a biomaterial vaccine based on mesoporous silica rods to spawn highly protective humoral responses against relevant antigens of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

8 Jul 2020

Workshops at the SMi 7th Annual Lyophilisation Conference

There are two interactive workshops taking place at the 7th annual Lyophilisation conference on the 5th June, featuring the analysis of physical properties and critical assessments.

2 May 2019

Synthetic biological logic gate could one day be used to modify cellular function

Genes in living cells are activated - or not - by proteins called transcription factors. The mechanisms by which these proteins activate certain genes and deactivate others play a fundamental role in many biological processes.

26 Mar 2019

Freeze dried polio vaccine could help save lives in remote locations

Polio vaccine can successfully prevent the deadly paralyzing illness caused in children. The vaccine presently available is in liquid form and is also thermolabile.

28 Nov 2018

KTU researchers engineer experimental bone to help treat osteoarthritis patients

Researchers from the Faculty of Chemical Technology, Kaunas University of Technology (KTU), Lithuania are developing an artificial bone, which can be used for treating of the most common joint disease - osteoarthritis.

26 Sep 2018

New simple flame burning method to prepare SWNT sponges on a large scale

In a paper published in NANO, a group of researchers have developed a simple flame burning method to prepare single-walled carbon nanotube (SWNT) sponges on a large scale. The SWNT sponge has multifunctional properties and can be used in the fields of cleaning-up, sensing and energy storage.

24 Aug 2018

New approach to cultivate hypoallergenic tomato and strawberry varieties

The incidence of food allergies has increased in recent decades: It affects three to four percent of the adult population and five percent of children.

16 Jul 2018

CellGenix completes first phase of facility expansion to meet rising demands for GMP cell culture reagents

CellGenix, a global manufacturing leader of GMP-grade raw materials for cell therapy, gene therapy and tissue-engineered products, successfully completed the first phase of its headquarters’ expansion as more customers approach late-stage clinical development and commercialization.

22 Jun 2018

Lithuanian researchers use freeze-drying technique to create sponge-like wound dressings

Group of researchers at Kaunas University of Technology, Lithuania are developing new generation sponge-like wound dressings with hyaluronic acid. Antimicrobial, antioxidant, anti-inflammatory wound dressings stimulate tissue regeneration and can be especially efficient in treating deep wounds that are difficult to heal.

12 Apr 2018

SP Scientific’s Freezemobile freeze dryer provides convenient, flexible solution for Life Science labs

The Freezemobile freeze dryer from SP Scientific is designed to provide a convenient and flexible solution for high-quality preparation of peptides, proteins, plant materials and organic tissue.

12 Feb 2018

Study confirms capabilities of SP Scientific’s new LyoCapsule Freeze Dryer

SP Scientific announces publication of an independent study evaluating their LyoCapsule Freeze Dryer for pharmaceutical product formulation and process development.

28 Nov 2017

Scientists develop antibacterial ‘sugar-glass’ coating that uses viruses to destroy bacteria

With antibiotic resistance on the rise, bacterial contamination of food is becoming more problematic. Now in a study appearing in ACS Biomaterials Science & Engineering, scientists report that they have developed an antibacterial "sugar-glass" coating in which viruses that destroy bacteria are embedded and are kept stable for up to three months.

8 Nov 2017

Lyophilization News and Research

Further Reading

New production method developed to freeze-dry COVID-19 vaccines

Cas13 shines a light on SARS-CoV-2 variants

Study shows efficacy of gamma irradiation of SARS-CoV-2 vaccine candidate in mouse model

COVID-19 PCR tests can withstand freeze-drying process

Protein-based vaccines against SARS-CoV-2 may provide advantages over mRNA-based vaccines

Researchers develop thermostable RNA vaccine delivery platform

Smart Evaporator Assists Medicinal Chemistry

SGD Pharma extends industry-leading Ready-to-Use molded glass vial range with introduction of EasyLyo and ISO20mm 50ml sizes in tray

A biomaterial vaccine for SARS-CoV-2 - quick and scalable

Workshops at the SMi 7th Annual Lyophilisation Conference

Synthetic biological logic gate could one day be used to modify cellular function

Freeze dried polio vaccine could help save lives in remote locations

KTU researchers engineer experimental bone to help treat osteoarthritis patients

New simple flame burning method to prepare SWNT sponges on a large scale

New approach to cultivate hypoallergenic tomato and strawberry varieties

CellGenix completes first phase of facility expansion to meet rising demands for GMP cell culture reagents

Lithuanian researchers use freeze-drying technique to create sponge-like wound dressings

SP Scientific’s Freezemobile freeze dryer provides convenient, flexible solution for Life Science labs

Study confirms capabilities of SP Scientific’s new LyoCapsule Freeze Dryer

Scientists develop antibacterial ‘sugar-glass’ coating that uses viruses to destroy bacteria

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