Neurodegenerative Disorder News and Research

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AI system spots Parkinson’s signs in voice, walking and drawings

Combining gait, handwriting, and speech analysis, this AI framework enhances early Parkinson's disease detection, addressing clinical challenges effectively.

3 Mar 2026

Investigating microglia’s role in Alzheimer’s pathology

Announcing a new article publication for BIO Integration journal. Alzheimer's disease (AD) is a neurodegenerative disorder and the leading cause of dementia worldwide. Microglia, as central nervous system (CNS) resident macrophages, are key to AD pathology. Indeed, microglia aggregation around amyloid-β (Aβ) deposits is an AD hallmark.

1 Mar 2026

Imaging technique can objectively identify a recently recognized type of dementia, LATE

A novel quantitative PET- and MRI-based imaging approach can objectively identify a recently recognized type of dementia--limbic-predominant age-related TDP-43 encephalopathy, or LATE--that is often mistaken as Alzheimer's disease.

26 Feb 2026

Novel lipid bubble delivery shows promise for ALS treatment

A researcher at the University of Missouri has made a promising breakthrough in the quest to help people with amyotrophic lateral sclerosis (ALS), the neurodegenerative disorder commonly known as Lou Gehrig's disease.

26 Feb 2026

Stem cell implants aim to restore dopamine in Parkinson’s disease

Parkinson's disease is a progressive neurodegenerative disorder that affects more than one million people in the United States, with approximately 90,000 new cases diagnosed each year.

5 Feb 2026

Inhibiting PTP1B protein improves memory in Alzheimer’s disease models

Alzheimer's disease is often measured in statistics: millions affected worldwide, cases rising sharply, costs climbing into the trillions.

5 Feb 2026

Blood gene signals reveal Parkinson’s risk years before diagnosis

Blood-based DNA repair and stress-response signals reveal early molecular changes in Parkinson's disease, aiding in potential early diagnosis and intervention.

2 Feb 2026

Gut problems may shape Parkinson’s disease progression through the gut-brain axis

This narrative review examines how gastrointestinal dysfunction, gut dysbiosis, and altered gut-brain axis signaling are closely associated with the onset and progression of Parkinson’s disease. It synthesizes evidence supporting a possible bottom-up disease model while highlighting integrative, gut-targeted strategies as adjuncts to symptom management rather than proven disease-modifying therapies.

27 Jan 2026

Adding lean pork to a plant-forward diet supports healthy aging biomarkers

A randomized crossover feeding trial in adults aged 65 years or older found that plant-forward diets incorporating either minimally processed lean pork or lentils produced similar short-term improvements in cardiometabolic and neuroactive biomarkers. Both diets supported metabolic health and functional stability, with no overall adverse biomarker effects attributable to including minimally processed red meat within a Dietary Guidelines–aligned pattern.

19 Jan 2026

Physical activity may help restore ease of movement and agility during aging

The brain-chemical surge that comes with running may bolster coordination and speed in the old and young alike, a new study of middle-aged mice shows.

9 Dec 2025

Restless legs syndrome linked to higher Parkinson’s disease risk

The study shows restless legs syndrome is associated with higher Parkinson's disease incidence, raising questions about treatment impacts on symptoms.

5 Dec 2025

Untreated restless legs syndrome may increase Parkinson's disease risk

Restless legs syndrome (RLS) is a common neurological sleep disorder characterized by an uncontrollable urge to move the legs, often worsening at night.

2 Dec 2025

UBQLN2 liquid droplets emerge as key catalysts of early α-synuclein aggregation

Parkinson's disease (PD) is an age-related, progressive neurodegenerative disorder. The hallmark of PD pathogenesis is the Lewy bodies (LBs) that accumulate in neurons in the substantia nigra region of the brain, damaging these neurons and leading to the motor symptoms of the disease.

26 Nov 2025

Researchers use "zap-and-freeze" technique to watch hard-to-see brain cell communications

Researchers at Johns Hopkins Medicine say they have used a "zap-and-freeze" technology to watch hard-to-see brain cell communications in living brain tissue from mice and humans.

25 Nov 2025

Researchers launch phase 2 trial to test swallowing therapy for people with early Parkinson's

Swallowing difficulties, or dysphagia, affect up to 80% of people with Parkinson's disease and can lead to serious complications, including malnutrition, aspiration and reduced quality of life.

24 Nov 2025

Oral arginine reduces amyloid buildup in Alzheimer’s models

Alzheimer's disease (AD), a progressive neurodegenerative disorder, is one of the leading causes of dementia worldwide, and currently has no definitive cure. Although antibody-based therapies that target amyloid β (Aβ) have recently been developed, their clinical effectiveness remains limited.

21 Nov 2025

Evaluating whether LIT supplementation slows cognitive decline in Alzheimer’s patients

Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline such as memory loss and behavioral disturbances that severely impair quality of life. Despite decades of research, effective disease-modifying therapies remain elusive, underscoring the urgent need for novel neuroprotective strategies.

19 Nov 2025

Dysfunctional mitochondria shown to initiate the onset of Parkinson's

For decades, scientists have known that mitochondria, which produce energy inside our cells, malfunction in Parkinson's disease.

17 Nov 2025

New diagnostic approach identifies dementia stages based on neurovascular and metabolic changes

Researchers from the Indiana University School of Medicine have developed a highly sensitive diagnostic that predicts a person's stage of dementia based on neurovascular and metabolic changes.

10 Nov 2025

Scientists create detailed single-cell map of the developing human brain

Scientists from Duke-NUS Medical School and their collaborators have created one of the most comprehensive single cell maps of the developing human brain. The atlas captures nearly every cell type, their genetic fingerprints, and how they grow and interact.

3 Nov 2025