Oral Cancer News and Research

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Oral cancer is the sixth most common type of cancer worldwide and in the U.S., one person dies every hour from the disease. According to American Cancer Society data, nearly as many women will be diagnosed with oral cancer as with cervical cancer this year. The key to reducing the impact of this disease is early detection.

Discovery of EUDAL reveals new mechanism behind chemotherapy resistance in oral cancer

Oral cancer is one of the most common head and neck cancers worldwide, with hundreds of thousands of new cases diagnosed every year. Despite advances in surgery, radiotherapy, and chemotherapy, survival rates remain poor.

30 Sep 2025

Can roselle help fight inflammation? New review suggests strong potential

A new review highlights the anti-inflammatory potential of Hibiscus sabdariffa (roselle), synthesizing evidence from 25 studies published between 2019 and 2024. Most findings are from preclinical models, but they point to promising roles in cardiovascular, metabolic, neuroprotective, and anticancer health.

28 Sep 2025

Colorectal cancer identified by its unique microbial fingerprint

Colorectal cancer is unique in having its own microbial 'fingerprint' – according to new research from the University of East Anglia.

3 Sep 2025

First clinical trial in cats tests targeted therapy for deadly head and neck cancer

Researchers have reported results from the first-ever clinical trial of a new class of targeted therapy in pet cats with head and neck squamous cell carcinoma (HNSCC)-a cancer which is notoriously deadly and difficult to treat.

28 Aug 2025

Early clinical trial supports MASL as a targeted oral cancer treatment

Rowan University and Sentrimed, a clinical-stage biopharmaceutical company focused on developing safer, orally dosed oncology therapies, today announced results from a National Cancer Institute (NCI) funded clinical trial evaluating MASL in patients with oral squamous cell carcinoma (OSCC).

8 Aug 2025

Cannabis use disorder triples five-year risk of oral cancer

Research shows cannabis use disorder triples the risk of oral cancer, challenging perceptions of cannabis safety and prompting calls for health screenings.

5 Aug 2025

Oral cancer risk triples among individuals with cannabis use disorder

A recent study by researchers at the University of California San Diego School of Medicine has found that individuals with cannabis use disorder (CUD) are more than three times more likely to develop oral cancer within five years compared to those without CUD.

29 Jul 2025

Synergistic effects of radiation and immunotherapy boost anti-tumor immunity

Head and neck squamous cell carcinomas (HNSCC) are a group of cancers that affect cells in and around our mouth and nose.

29 Jul 2025

Hydrogels could be key to safer, smarter cancer drug delivery

Hydrogels could revolutionize cancer treatment by facilitating targeted drug delivery, reducing adverse effects, and enhancing therapeutic effectiveness.

11 Jul 2025

How hydrogels are shaping the future of targeted cancer drug delivery

A large-scale bibliometric analysis maps global research on hydrogels as next-generation drug delivery systems for cancer therapy. The study highlights emerging trends, key contributors, and future directions to advance precision medicine in oncology.

10 Jul 2025

RANBP2 identified as key regulator in the progression of multiple solid tumors

The nuclear pore complex protein RANBP2 has emerged as a critical factor in the development and progression of various solid malignancies.

12 May 2025

Blocking LSD1 restores immune response in early oral cancer

Oral squamous cell carcinoma (OSCC) is a leading cause of cancer-related deaths, and early detection is key to improving patient outcomes. However, the mechanisms driving the transition from preneoplastic lesions to full-blown cancer are not well understood.

11 May 2025

Targeting METTL3 may offer new hope for oral cancer treatment

A new research paper was published in Oncotarget, Volume 16, on May 8, 2025, titled "METTL3 promotes oral squamous cell carcinoma by regulating miR-146a-5p/SMAD4 axis."

11 May 2025

Medicare changes set to lower out-of-pocket costs for cancer medications

Even for patients covered by Medicare, annual out-of-pocket costs for lifesaving cancer treatments taken in pill form have often exceeded $10,000-until recently.

28 Apr 2025

New Medicare changes ease cost burden for cancer drugs

Even for patients covered by Medicare, annual out-of-pocket costs for lifesaving cancer treatments taken in pill form have often exceeded $10,000-until recently.

25 Apr 2025

Powerful new tool promises major advances in cancer treatment

New Australian technology is set to transform the way that gastrointestinal cancers are detected and treated with precise, minimally invasive surgery.

8 Apr 2025

New quantum technology set to revolutionize gastrointestinal cancer detection and treatment

New Australian technology is set to transform the way that gastrointestinal cancers are detected and treated with precise, minimally invasive surgery.

7 Apr 2025

AI and deep learning transform diagnosis of oral potentially malignant disorders

Oral cancer remains a serious global health concern due to its high morbidity and mortality rates, primarily caused by late-stage diagnosis.

26 Feb 2025

Study reveals how healthy stem cells transform into cancer cells

Nearly 60,000 people are diagnosed with oral cancer in the U.S. every year, according to the American Cancer Society, and the rate of new cases continues to rise.

5 Feb 2025

Unveiling the metabolic pathways of Fusobacterium nucleatum in OSCC

A recent study has made significant strides in uncovering how the oral microbiome, particularly the bacterium Fusobacterium nucleatum, plays a crucial role in the progression of oral squamous cell carcinoma (OSCC). By identifying key interactions between this common oral bacterium and host cells, the research has unveiled important metabolic pathways and mechanisms that may serve as potential therapeutic targets.

17 Jan 2025