Spasticity News and Research

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Spasticity is a condition involving an involuntary increase in muscle tone that leads to resistance against normal movements of the body and may cause pain in some individuals.

SPG-15: A Mother's Fight for a Gene Therapy Cure, Maddi's Story

News Medical spoke to the CEO and founder of the Maddi Foundation to gain a patient perspective on how important research in gene therapy is.

3 Jul 2023

Study reveals biologically validated imaging-based evidence of medically induced myelin repair

A decade after UC San Francisco scientists identified an over-the-counter antihistamine as a treatment for multiple sclerosis, researchers have developed an approach to measure the drug's effectiveness in repairing the brain, making it possible to also assess future therapies for the devastating disorder.

13 Jun 2023

Spasticity in the lower extremities linked to higher odds of cryptorchidism in boys with cerebral palsy

Cerebral Palsy has been linked to a condition called cryptorchidism in males - when one or both of the testicles are not present in the scrotum.

7 Jun 2023

Special issue aims to deepen the conversation around cerebral palsy

Although cerebral palsy (CP) is the most common childhood-onset disability, there are very few evidence-based clinical practice guidelines or recommendations on how to treat and manage this condition.

31 May 2023

Defective proteins involved in ER-phagy can cause neurodegenerative diseases

Our cells are crisscrossed by a system of membrane tubes and pockets called the endoplasmic reticulum (ER). It is crucial for the production of biomolecules and is continuously built up and degraded.

26 May 2023

Is medical cannabis treatment associated with improvements in health-related quality of life?

Researchers investigated whether cannabis treatment could improve the health-associated quality of life.

11 May 2023

Researchers discover a new role for one of the genes linked to hereditary spastic paraplegia

Researchers from the University of Seville and the Seville Institute of Biomedicine (IBiS), in collaboration with the University of Cambridge, have identified a new role for one of the genes related to hereditary spastic paraplegia.

27 Mar 2023

Study assesses the effect of transcutaneous spinal stimulation on intrathecal baclofen pump in patients with spinal cord injury

Researchers from Kessler Foundation and Kessler Institute for Rehabilitation (collectively "Kessler") conducted the first prospective study to assess whether transcutaneous spinal stimulation (TSS) interacts with implanted intrathecal baclofen (ITB) pump delivery systems for managing spasticity.

21 Mar 2023

Black and Hispanic stroke survivors in the U.S. less likely to be treated for certain complications

Analysis of 20 years of electronic health records across the U.S. finds Black and Hispanic stroke survivors were less likely than white stroke survivors to receive treatment for common complications during the first year after their stroke, according to preliminary research to be presented at the American Stroke Association's International Stroke Conference 2023.

2 Feb 2023

Botox treatment may lessen anxiety

Botox, or Botulinum toxin, a medication derived from a bacterial toxin, is commonly injected to ease wrinkles, migraines, muscle spasms, excessive sweating and incontinence.

22 Dec 2022

HU begins human trial for promising treatment to reverse paralysis and language disorder after stroke

Hiroshima University started the human trial for a promising treatment that offers hope in potentially reversing paralysis and language disorder after moderate to severe stroke using therapeutically superior mesenchymal stem cells (MSCs) derived from the cranial bone.

1 Dec 2022

Designing a new treatment to treat migraine effectively

In this interview, we speak to Mudra Kapoor, Vice President of Global Medical Affairs for Neuroscience at AbbVie, about atogepant, their new treatment option for migraine.

From AbbVie 26 Sep 2022

High-quality human clinical trials needed to determine the benefits of CBD for heart disease patients

As cannabidiol (CBD) use rises, high quality randomized clinical trials are needed to determine if anti-inflammatory benefits of CBD for heart disease seen in preclinical data will work in a real-world setting, according to research presented at ACC Latin America 2022 Together with CardioAcademic.

5 Sep 2022

AbbVie Submits Marketing Authorization Application to EMA for Atogepant for the Preventive Treatment of Migraine

AbbVie today announced it has submitted a marketing authorization application (MAA) to the European Medicines Agency (EMA) for atogepant for the prophylaxis of migraine in adult patients who have at least four migraine days per month.

From AbbVie 21 Jul 2022

Dr. Wall named as director of pediatric and adolescent orthopedics division

Lindley B. Wall, MD, a professor of orthopedic surgery and a member of the Department of Orthopaedic Surgery's hand and microsurgery service, has been named director of the Division of Pediatric and Adolescent Orthopedics at Washington University School of Medicine in St. Louis.

7 Jul 2022

Current evidence on cannabis use in palliative care

Scientists from Wellington, New Zealand, have conducted a systematic review to understand the effectiveness of medicinal cannabis in palliative care settings.

13 Jun 2022

3D-printed bracelet may allow people with hand-impairment to use computers, play video games

People who lack the ability to use their hands from conditions like motor neurone disease and cerebral palsy may one day be able to play video games that require a handheld controller through the use of acustomisable, wearable 3D printed bracelet.

4 May 2022

Domestic violence survivor, UK patient stands and walks for the first time in more than eight years

"Deep breaths, April. Deep breaths." April Ballentine nods, steeling herself. As she sits inside the lab of the University of Kentucky's Sports Medicine Research Institute (SMRI), her anticipation stirs up an incredible amount of pure nervousness.

1 Apr 2022

Genetic diagnosis in cerebral palsy patients could change the approach to care

Cerebral palsy, a non-progressing motor impairment that begins in early childhood, has widely been viewed as the result of oxygen deprivation during birth or other birth-related factors such as prematurity.

25 Jan 2022

Engineer receives $2.1 million grant to test a treatment strategy for children with cerebral palsy

Mechanical engineer and inventor Zach Lerner, assistant professor in Northern Arizona University's Department of Mechanical Engineering, has been awarded $2.1 million by the National Institutes of Health's Eunice Kennedy Shriver National Institute of Child Health & Human Development.

3 Jan 2022