Tetanus News and Research

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Tetanus is a severe, frequently fatal disease caused by an exotoxin produced by Clostridium tetani, a bacterium that is found in the environment. Tetanus is not transmitted from person to person. Rather, Clostridium tetani enters the body through an open wound, including lacerations, abrasions and puncture wounds. The toxin causes neuromuscular dysfunction, with rigidity and spasms of skeletal muscles. The muscle spasms usually start in the jaw (which is why the disease is sometimes called "lockjaw") and neck and may spread to many other muscles, leading to generalized paralysis.

Waning immunity and falling vaccination rates fuel pertussis outbreaks

Rates of pertussis, also known as whooping cough, are surging in Texas, Florida, California, Oregon, and other states and localities across the country.

20 Nov 2025

Conflicting advice on covid shots likely to ding already low vaccine rates, experts warn

More than three-quarters of American adults didn't get a covid shot last season, a figure that health care experts warn could rise this year amid new U.S. government recommendations.

14 Nov 2025

COVID-19 pandemic linked to diminishing public trust in childhood vaccines

An international study led by the Azrieli Faculty of Medicine in the Galilee at Bar-Ilan University reveals that the COVID-19 pandemic has contributed to a diminishing public trust in childhood vaccines, resulting in declining vaccination rates and a resurgence of preventable, life-threatening diseases such as measles.

28 Oct 2025

Doctors muffled as Florida moves to end decades of childhood vaccination mandates

Florida plans to end nearly a half-century of required childhood immunizations against diseases that have killed and maimed millions of children. Many critics of the decision, including doctors, are afraid to speak up against it.

27 Oct 2025

Gene therapy shows long-term success in children with rare immune disorder

Results from the largest cohort of children who received a gene therapy for a rare immunodeficiency condition have shown the long-term safety and efficacy of the curative treatment, in a study led by a UCL researcher.

15 Oct 2025

Study finds lower vaccine uptake in children from certain socioeconomic and migration backgrounds

In the Netherlands, the National Immunisation Programme (NIP) was established in 1957. This programme provides free and voluntary vaccinations against 13 serious infectious diseases and has drastically reduced child and young adult mortality across the country.

10 Oct 2025

Yale researchers develop new test for early leptospirosis detection

In a new study, Yale School of Medicine (YSM) researchers unveiled a novel diagnostic method for detecting leptospiral virulence-modifying (VM) proteins in the blood and urine of hamsters, an advance that could pave the way for early diagnosis of the tropical disease leptospirosis in humans and improved treatment options.

29 Sep 2025

‘Alternative facts’ aren’t a reason to skip vaccines

President Donald Trump's administrations have been notorious for an array of "alternative facts" — ranging from the relatively minor (the size of inaugural crowds) to threats to U.S. democracy, such as who really won the 2020 election.

14 Aug 2025

Childhood and adolescent immunizations decline in Michigan, study shows

Routine childhood and adolescent immunizations declined in Michigan between 2017 and 2023, particularly among counties with lower household income and higher uninsurance rates, a new study suggests.

11 Aug 2025

Understanding the biomarkers and mechanisms associated with anti-NMDAR encephalitis

Encephalitis is a potentially life-threatening condition that involves inflammation of the brain. While some cases of encephalitis are caused by a bacterial or viral infection, other cases of 'autoimmune' encephalitis result when the body's own immune system attacks the brain.

8 Aug 2025

Expanded vaccine screening in emergency departments could benefit underserved populations

About 49% of people are unaware of one or more vaccines recommended for them. Further, 86% have not received one or more of these vaccines.

7 Aug 2025

Forever chemicals cross placenta and breast milk affecting babies’ immunity

New research reveals that tiny amounts of PFAS-widely known as "forever chemicals"-cross the placenta and breast milk to alter infants' developing immune systems, potentially leaving lasting imprints on their ability to fight disease.

23 Jul 2025

Over 14 million children miss lifesaving vaccines threatening global goals

More than 14 million children missed out on lifesaving vaccines against diphtheria, tetanus and whooping cough last year, putting global goals off track, new UN data shows.

22 Jul 2025

Aluminum vaccines cleared of long-term health risks

Findings from a cohort of 1.2 million children indicate aluminum-adsorbed vaccines do not raise the risk of autism, asthma, or autoimmune diseases.

17 Jul 2025

Routine vaccines may be the key to fighting antibiotic resistance

A study reveals that rising vaccine coverage in children is linked to reduced antibiotic prescriptions, suggesting a shift in the fight against drug resistance.

16 Jul 2025

U.S. could safely end routine adult tetanus and diphtheria shots, review suggests

The United States could safely drop tetanus and diphtheria booster shots for adults and save an estimated $1 billion a year, according to a new review led by researchers at Oregon Health & Science University.

15 Jul 2025

WHO and UNICEF urge action to protect children through vaccines

In 2024, 89% of infants globally – about 115 million – received at least one dose of the diphtheria, tetanus and pertussis (DTP)-containing vaccine, and 85% – roughly 109 million – completed all three doses, according to new national immunization coverage data released today by the World Health Organization (WHO) and UNICEF.

15 Jul 2025