Tissue Engineering News and Research

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Dramatic advances in the fields of biochemistry, cell and molecular biology, genetics, biomedical engineering and materials science have given rise to the remarkable new cross-disciplinary field of tissue engineering. Tissue engineering uses synthetic or naturally derived, engineered biomaterials to replace damaged or defective tissues, such as bone, skin, and even organs.

Modulating pathogenic scar cells promotes spinal cord regeneration

SCI often causes long-term motor and sensory deficits because the damaged tissue does not simply heal like many peripheral tissues.

24 Jun 2026

Melatonin improves skin flap survival by reducing ferroptosis

Random-pattern skin flaps are widely used to repair defects caused by trauma, burns, tumor removal, and other injuries because they can be designed without depending on a single named blood vessel.

23 Jun 2026

Researchers identify molecular pathway that delays diabetic wound healing

Diabetic foot ulcer (DFU) is one of the most serious complications of diabetes and a major cause of lower-limb amputation.

23 Jun 2026

Skin barrier monitoring predicts necrosis after skin flap surgery

Random-pattern skin flaps (RPSFs) receive blood mainly from small subcutaneous vessels rather than a defined axial vessel, leaving them vulnerable to ischemia and hypoxia after surgery.

23 Jun 2026

Engineered cartilage grafts improve surgery for narrowed child airways

A study led by researchers at Children's Hospital of Philadelphia (CHOP) demonstrated a new method of using decellularized cartilage with patient-specific cells to help enlarge the pediatric airways narrowed as a result of severe subglottic stenosis.

17 Jun 2026

New low-cost artificial mitral valve mimics human tissue to study disease

Researchers at RCSI University of Medicine and Health Sciences have developed an artificial model of the mitral heart valve that faithfully mimics the valve's complex mechanical behavior in the human heart.

11 Jun 2026

New topical gel uses repurposed MS drug to heal burns

Researchers at the Terasaki Institute for Biomedical Innovation and the University of Arizona College of Medicine have developed a topical gel formulation with 4-aminopyridine (4-AP), to treat burn wounds, achieving near-complete closure in 21 days.

4 Jun 2026

Scientists develop mineralized DNA hydrogel to accelerate bone repair

A new study developed a mineralized DNA hydrogel that combines immune regulation with sustained bone regeneration.

3 Jun 2026

New ‘heart-on-a-chip’ to halt cardiac damage caused by Duchenne

Duchenne Parent Project Spain (DPPE) has launched the BEAT Project, a research initiative focused on one of the key challenges associated with Duchenne and Becker muscular dystrophies: progressive heart damage. Cardiomyopathy is the leading cause of death in patients with DMD.

7 May 2026

Cells filter physical forces based on duration to detect disease

Scientists have discovered how cells decide when to respond to physical forces, potentially opening new avenues for tackling diseases such as cancer and fibrosis.

29 Apr 2026

Synthetic biology approach boosts growth of implanted liver tissue

In patients developing end-stage liver disease, the damage has become too severe for the liver's normally extraordinary regenerative capacity to repair or compensate for it. Once this "point of no return" has been reached, the only option is an organ transplant.

17 Apr 2026

Microneedle nanoparticle platform improves lymphatic imaging with high resolution

The lymphatic system plays a critical role in pathological conditions such as lymphedema and chronic inflammation to tumor metastasis, venous insufficiency, and impaired wound healing, making accurate evaluation of its structure and function increasingly important.

13 Apr 2026

Metformin protects neurons after brain injury by restoring mitochondrial health

TBI remains a major cause of death and long-term neurological disability worldwide, yet effective treatments for secondary injury are still lacking.

13 Apr 2026

Extracellular vesicles from menstrual blood cells show potential to stimulate cartilage repair

New research by an interdisciplinary team in Lithuania has revealed a promising and unconventional approach to cartilage regeneration.

10 Apr 2026

Childhood trauma inspires research into brain repair and recovery

What began as a child's encounter with trauma has grown into a research programme committed to understanding recovery.

7 Apr 2026

New method identifies key proteins that trigger harmful immune responses

Mayo Clinic researchers have developed a new method to identify which proteins are most likely to trigger an immune response - a discovery that could help improve transplant care, regenerative medicine and other areas where the immune system plays a critical role.

6 Apr 2026

Study reveals molecular control of tooth root formation and growth

Tooth root development relies on precise coordination of cellular signals, yet the underlying mechanisms remain unclear. Researchers have uncovered how two proteins, Gli2 and Gli3, work together to control signaling and differentiation in dental progenitor cells.

1 Apr 2026

New skin atlas maps over one million cells across the human body

Mount Sinai researchers have published the first organ-wide human skin spatial atlas from across the body.

25 Mar 2026

New nanomaterial enhances bioimaging and targeted cancer drug delivery

The Nanomedicine and Nanotoxicology Group (GNano) at the University of São Paulo's São Carlos Institute of Physics (IFSC-USP) in Brazil has discovered a way to transform hydroxyapatite, a bioceramic material, into a nanoparticle with enhanced intrinsic luminescence.

18 Mar 2026