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First European trial tests CAR T therapy in amyloidosis patients

Three patients with light chain amyloidosis have been treated with CAR T cell therapy in the first European clinical trial testing the safety and efficacy of this immunotherapy in this patient group, led by UCL and UCLH researchers.

6 May 2026

GLP-1 weight-loss drugs modulate brain reward circuits to suppress eating for pleasure

A National Institutes of Health (NIH)-funded study has found that an emerging class of GLP-1 weight-loss drugs suppress eating for pleasure, or hedonic feeding, in mice by modulating a reward circuit deep within the brain.

6 May 2026

Calla Lily Clinical Care doses first patients in clinical trial for intravaginal drug delivery platform for threatened miscarriage

Calla Lily Clinical Care, a women’s health-focused medical technology company, today announced dosing of the first patients in the FREEDOM clinical trial.

6 May 2026

App launched to track heart health after high-risk pregnancies

The MumCare app addresses postpartum cardiovascular risk, supporting women in managing health after pregnancy complications through personalized digital tools.

6 May 2026

Virtual reality training improves police interactions for autistic individuals

A new study led by researchers at Children's Hospital of Philadelphia and St. Joseph's University found that an innovative virtual reality intervention was helpful for improving interactions between autistic teens and adults and law enforcement officers.

5 May 2026

Phase 2 human clinical trial paves way for effective hookworm vaccine

A phase 2 human clinical trial of an antigen for a parasitic infection caused by hookworms has been shown to be effective in limiting the intensity of infection, paving the way for the development of a vaccine.

5 May 2026

Study highlights stigma surrounding popular GLP-1 weight loss drugs

Glucagonlike peptide-1 (GLP-1) medications have taken over the national conversation around weight loss.

4 May 2026

EVALI outbreak reshaped public perceptions of e-cigarette harm

Cigarettes are one of the deadliest products on the market – but the risks of alternatives are not always clearly understood.

4 May 2026

NIH awards $3.9 million grant to develop a non-opioid pain treatment

The National Institute of Neurological Disorders and Stroke, part of the National Institutes of Health (NIH), has awarded a $3.9 million grant to a multi-institutional team led by scientists at Sanford Burnham Prebys Medical Discovery Institute to develop a non-opioid pain therapeutic and advance it into a Phase 1 clinical trial.

4 May 2026

NIH grant fuels NYU Langone efforts to accelerate medical research discoveries

NYU Langone Health has been awarded a nearly $70 million, seven-year renewal grant from the National Institutes of Health (NIH) to fund its Clinical and Translational Science Institute (CTSI). The award is the highest level of funding available nationally under NIH's Clinical and Translational Science Awards (CTSA) Program.

4 May 2026

Finding new ways to mimic ketamine’s antidepressant effects

Weill Cornell Medicine investigators have "reverse engineered" ketamine's antidepressant effects to identify potential new strategies for treating depression.

4 May 2026

Semaglutide as a promising new treatment for alcohol use disorder

Research indicates semaglutide can significantly decrease alcohol consumption and cravings in individuals with comorbid obesity and alcohol use disorder.

4 May 2026

Researchers leverage tamoxifen's active metabolite to improve breast cancer prevention

Low doses of the investigational medicinal product endoxifen reduce breast density to the same extent as the standard treatment tamoxifen, but without causing such troublesome side effects. This is shown by a new study from Karolinska Institutet published in the Journal of the National Cancer Institute. The results may have implications for future preventive treatment of breast cancer.

4 May 2026

Gentler treatment improves survival in children with relapsed leukemia

A gentler treatment for children whose leukemia has come back could boost survival and quality of life, a study led by a UCL academic has found.

30 Apr 2026

New CAR T cell design boosts persistence and reduces toxicity

CAR T-cell therapy has transformed the treatment of hematologic malignancies, yet many patients do not achieve lasting benefit – often because the infused cells fail to expand or persist.

30 Apr 2026

Liquid biopsy predicts immune response in high-risk breast cancer patients

Immunotherapy has become a standard of care in treating high-risk, early-stage breast cancers, yet it has had limited success in shrinking tumors.

30 Apr 2026

Eliminating animal products reshapes metabolic health and environmental impact

A new randomized clinical trial provides some of the clearest evidence to date that what we eat can meaningfully reshape both human health and the health of the planet.

30 Apr 2026

From killers to strategists: CAR T cells enter their multifunctional era

A review of 1,801 registered CAR T clinical trials shows that multifunctional designs now account for 533 trials and 33% of new CAR T products submitted for clinical testing in 2025. The field is shifting toward multitargeted, safety-controlled, cytokine-secreting, and checkpoint-modulating CAR T cells, but manufacturing, regulation, and limited clinical outcome data remain key barriers.

30 Apr 2026

New brain stimulation technique improves social communication in children with autism

A new non-invasive brain stimulation technique known as accelerated continuous theta burst stimulation (a-cTBS) improves social communication at one month follow up and has a favorable safety profile in children with autism, finds a trial from China published by The BMJ today.

29 Apr 2026