Membrane News and Research

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New algae gel provides realistic platform for breast cancer research

In 2020, right when Jane Baude was starting her Ph.D. research at UC Santa Barbara, she learned that a critical component of her experiment - the gel needed to grow and test mammary epithelial cells - wouldn't be available for nearly a year because of pandemic-related production issues. So, she and her adviser, professor Ryan Stowers, decided to pivot: Baude would engineer her own gel to study cells.

3 Oct 2025

Scientists discover new protein family regulating motility and DNA uptake

Bioengineers at the University of California San Diego have developed a powerful new technology that can map the entire network of RNA-protein interactions inside human cells - an achievement that could offer new strategies for treating diseases ranging from cancer to Alzheimer's.

3 Oct 2025

Restoring delta cell function may prevent dangerous hypoglycemic events in diabetes

A new study by the University of California, Davis, shows how cells work together to avoid a sudden drop in blood sugar. Understanding these feedback loops could improve the lives of people with diabetes and help them avoid dangerous hypoglycemia.

3 Oct 2025

New insights into how antimicrobial peptides kill bacterial cells

New research into antimicrobial peptides, small chains of amino acids able to damage bacterial cells, shows why some peptides are more effective at doing that and also why some cells are more vulnerable.

2 Oct 2025

How the University of Manchester used Bruker equipment to map the dynamics of complex protein

Discover how Bruker and the University of Manchester joined forces to discover more on the dynamics of complex protein.

From Bruker BioSpin Group 2 Oct 2025

High-resolution imaging reveals how polymyxins trigger rapid shedding of bacterial armor

A team led by UCL (University College London) and Imperial College London researchers has shown for the first time how life-saving antibiotics called polymyxins pierce the armor of harmful bacteria.

30 Sep 2025

Combining radiopharmaceuticals with targeted radiation improves progression-free survival in prostate cancer patients

A new clinical trial finds that people with a limited number of metastases from recurrent prostate cancer lived significantly longer without disease progression when they received a radiopharmaceutical drug before targeted radiation, compared with radiation alone.

29 Sep 2025

Super-resolution imaging unlocks the role of transporter nanoclusters in tumor metabolism

Serine serves as a metabolic nexus in tumors, coordinating one-carbon metabolism, nucleotide synthesis, and redox regulation. In recent years, targeting the serine metabolic pathway, particularly the rate-limiting enzyme PHGDH, has attracted considerable attention as a promising anticancer strategy.

29 Sep 2025

Gut probiotic Christensenella tenuis reduces endotoxemia and improves metabolism in obese mice

This study is reported by the team of Professor Shuang-jiang Liu from Shandong University. The study reveals that the gut probiotic Christensenella tenuis significantly alleviates endotoxemia and metabolic disorders in a diet-induced obesity (DIO) mouse model by modulating gut bile acids (BAs) metabolism and suppressing lipopolysaccharide (LPS) translocation across the gut barrier.

26 Sep 2025

Pediatric lung transplantation shows promising outcomes in China

Lung transplantation has transformed care for patients with end-stage respiratory failure, particularly among adults, where the number of procedures has grown dramatically over recent decades.

25 Sep 2025

Blocking iron-regulating enzyme triggers cancer cell death in multiple myeloma

Researchers at Duke University have shown that blocking an enzyme involved in iron regulation not only kills multiple myeloma cancer cells, but also increases the effectiveness of current therapies against the disease.

24 Sep 2025

Consumption of ultra-processed foods may exacerbate disease activity in early multiple sclerosis

Higher intake of ultra-processed foods (UPFs) may exacerbate disease activity in early multiple sclerosis (MS), according to new research presented at the 41st Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS 2025).

24 Sep 2025

Groundbreaking discovery could transform leishmaniasis treatment

Leishmaniasis, a neglected tropical disease prevalent across 90 countries, affects approximately 12 million people worldwide, with 350 million more at risk of infection.

24 Sep 2025

GPR120 plays a key role in mediating the effects of n-3 fatty acids on mammary function

During lactation, the mammary gland undergoes significant structural and functional changes to produce milk, which is essential for neonatal nutrition and early immune development.

23 Sep 2025

Study provides new insights into the mechanisms of fetal membrane healing

When a pregnant woman's water breaks too early, it often leads to preterm birth, with no effective method to prevent or treat it.

23 Sep 2025

Understanding how lipids activate LC3-associated phagocytosis

LC3-associated phagocytosis (LAP) is a specialized process for degrading dead cells, microbes or other particles. It plays a role in innate immunity, inflammation regulation and anticancer responses.

23 Sep 2025

Magnetically-powered nanorobots enhance drug uptake in tumors

Spiky nanorobots powered by magnets have been developed to carry drugs and pierce tumor cell membranes, a key barrier to effective cancer treatment. By boosting drug entry, these "microscopic scalpels" improved chemotherapy results in laboratory and animal studies, suppressing tumor growth and extending survival.

22 Sep 2025

PRMT5 inhibition induces ferroptosis and enhances immunotherapy efficacy in renal cell carcinoma

Ferroptosis, a regulated cell death mechanism, is emerging as a promising target for cancer therapy. The process is mediated by the activity of acyl-CoA synthetase family member 4 (ACSL4) protein.

22 Sep 2025

Lysosomal acidity fine-tunes reactive species production in macrophages

Macrophages rely on lysosomes to balance microbial killing with self-protection, generating reactive oxygen and nitrogen species during phagocytosis.

21 Sep 2025

New quintuple agonist shows promise for treating obesity and type 2 diabetes

Much excitement has built in recent years on the new class of incretin drugs that include glucagon-like-peptide-1 inhibitor (single agonists such as semaglutide) and also dual glucose-dependent insulinotropic polypeptide (GIP) and GLP-1 receptor agonists (dual agonists such tirzepatide).

21 Sep 2025

Membrane News and Research

New algae gel provides realistic platform for breast cancer research

Scientists discover new protein family regulating motility and DNA uptake

Restoring delta cell function may prevent dangerous hypoglycemic events in diabetes

New insights into how antimicrobial peptides kill bacterial cells

How the University of Manchester used Bruker equipment to map the dynamics of complex protein

High-resolution imaging reveals how polymyxins trigger rapid shedding of bacterial armor

Combining radiopharmaceuticals with targeted radiation improves progression-free survival in prostate cancer patients

Super-resolution imaging unlocks the role of transporter nanoclusters in tumor metabolism

Gut probiotic Christensenella tenuis reduces endotoxemia and improves metabolism in obese mice

Pediatric lung transplantation shows promising outcomes in China

Blocking iron-regulating enzyme triggers cancer cell death in multiple myeloma

Consumption of ultra-processed foods may exacerbate disease activity in early multiple sclerosis

Groundbreaking discovery could transform leishmaniasis treatment

GPR120 plays a key role in mediating the effects of n-3 fatty acids on mammary function

Study provides new insights into the mechanisms of fetal membrane healing

Understanding how lipids activate LC3-associated phagocytosis

Magnetically-powered nanorobots enhance drug uptake in tumors

PRMT5 inhibition induces ferroptosis and enhances immunotherapy efficacy in renal cell carcinoma

Lysosomal acidity fine-tunes reactive species production in macrophages

New quintuple agonist shows promise for treating obesity and type 2 diabetes

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Expanding access to NMR with the Fourier 80 Duo