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Study reveals how liver bile composition changes during enteric infections

Intestinal infections can change the composition of liver bile, leading to changes in immune function and gut bacteria, potentially helping fight off harmful bacteria .

26 Nov 2024

New technology enables rapid detection of TNT metabolites in the human body

Recently, a research group led by Prof. HUANG Chaoqun from the Hefei lnstitutes of Physical Science of the Chinese Academy of Sciences, developed an innovative dual drift tube ion mobility spectrometry (DDT-IMS) technology.

22 Nov 2024

Fermented kimchi may help combat obesity by regulating gut microbiota

Kimchi consumption significantly reduces body fat and enhances metabolic indicators in overweight individuals, highlighting its role in obesity management.

22 Nov 2024

Small brain-penetrating molecule offers hope for treating aggressive brain tumors

Gliocidin selectively kills glioblastoma cells by inhibiting nucleotide synthesis, showing potential as a therapeutic option in combination with temozolomide.

21 Nov 2024

SARS-CoV-2 hijacks cholesterol trafficking to fuel infection and evade immune responses

SARS-CoV-2 disrupts cholesterol metabolism by using its ORF3a protein to sequester cholesterol in lysosomes, reducing BMP levels and optimizing viral survival. This novel mechanism offers insights into long-term metabolic complications of COVID-19.

19 Nov 2024

MSU researchers develop method for earlier disease detection using blood proteins

Medical professionals have long known that the earlier a disease is detected, the higher the chance for a better patient outcome.

19 Nov 2024

Sapio Sciences Collaborates with Waters Corporation to Improve Efficiency of Laboratory Operations

The advanced connectivity of Sapio LIMS with waters_connect for Quantitation liquid chromatography mass spectrometry (LC-MS) software.

From Sapio Sciences 18 Nov 2024

Spermidine regulates RIPK1 to combat diabetes and vascular damage

Researchers reveal that spermidine-mediated acetylhypusination of RIPK1 suppresses necroptosis and insulin resistance, offering potential therapeutic strategies for type 2 diabetes.

18 Nov 2024

EASI algorithm set to transform forensic drug identification processes

Relief is coming for crime scene investigators and toxicologists who have struggled to accurately and swiftly identify drugs that have been seized by law enforcement and may be relied on as evidence at trial, thanks to a research partnership between West Virginia University and the U.S. Drug Enforcement Administration.

15 Nov 2024

Key reason why some cancers do not respond to immunotherapy identified

Research reveals SLC13A3's role in tumor cell survival and immune therapy resistance, highlighting its potential as a target for improved cancer treatments.

12 Nov 2024

Traditional Chinese herb shows promise against Alzheimer’s and Parkinson’s

Zizyphi spinosi semen demonstrates neuroprotective effects, improving cognitive function and reducing amyloid and tau pathology in models of aging and dementia.

8 Nov 2024

Scientists discover how the keto diet may help some people with multiple sclerosis

Scientists have long suspected the keto diet might be able to calm an overactive immune system and help some people with diseases like multiple sclerosis.

4 Nov 2024

Study identifies cellular and molecular roots of individual brain connectivity differences

Researchers link microscopic protein structures and cellular interactions to individual differences in brain connectivity, offering new insights into brain function and variability.

3 Nov 2024

Combination therapy shows promising results in treating stage 3 melanoma

Pre-surgery treatment with the novel drug vidutolimod and the PD-1 checkpoint inhibitor nivolumab led to tumor control in 55% of patients with stage 3 cutaneous melanoma, according to the results of a single-arm phase 2 clinical trial led by the University of Pittsburgh, UPMC Hillman Cancer Center and the National Cancer Institute (NCI).

1 Nov 2024

New study links childhood BMI trajectories to adult lung health

Researchers examine interactions between early life body mass index values and later life lung function.

1 Nov 2024

Study compares metabolism of humantenirine in human, pig, and goat liver microsomes

Gelsemium elegans Benth (G. elegans) is a traditional medicinal plant; however, it is highly toxic, and toxicity varies significantly between species.

30 Oct 2024

Enzyme from gut microbe shows promise in fighting childhood malnutrition

The study highlights FAAH's role in gut microbiota, showing its potential in improving growth and health in malnourished children through dietary intervention.

29 Oct 2024

New imaging technique revolutionizes microplastics detection in biological samples

Microplastics, pervasive in both terrestrial and aquatic environments, have been found in diverse organisms, from fish and plants to humans.

28 Oct 2024

MALDI-TOF mass spectrometry proves effective for diagnosing onychomycosis in nail psoriasis

Nail psoriasis is common in patients with plaque psoriasis and is associated with morbidity, including onychomycosis, which can complicate psoriasis treatments and be difficult to differentiate.

26 Oct 2024

Taurine supplementation linked to reduced atherosclerotic plaque development

Previous studies suggest that taurine supplementation may attenuate atherosclerosis by reducing lipid levels. However, energy drinks containing taurine have been shown to increase blood pressure, a key risk factor for atherosclerosis. Thus, the role of taurine in atherosclerosis remains controversial.