Spectrometry News and Research

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SCIEX summit - Highlighting scientific breakthroughs in mass spectrometry that really count

Join scientists and researchers from around the globe to discuss the importance of LC-MS in fields like food and environmental testing, pharmaceutical and biopharmaceutical discovery and development and biomedical and omics research.

From SCIEX 9 Sep 2024

Cosmochemistry techniques shed light on potential new Alzheimer's disease biomarker

The study identifies lower potassium isotope ratios in Alzheimer's patients, suggesting δ41K as a viable biomarker for early detection of the disease.

9 Sep 2024

Researchers uncover connection between two common diabetes drugs with implications for foot ulcer healing

Research shows elevated metformin in diabetic foot ulcer exudates when combined with insulin, highlighting potential for improved wound healing therapies.

9 Sep 2024

Study reveals how sex hormones regulate immune system functions

Findings indicate that testosterone therapy in trans men alters immune system responses, suggesting implications for disease susceptibility and treatment.

6 Sep 2024

Auburn University researchers develop AI-driven method to target cancer proteins

Researchers at Auburn University, in collaboration with scientists from the University of Basel and ETH Zurich, have made a groundbreaking advance in the fight against cancer.

5 Sep 2024

How mosquito spit could help develop therapies for arboviral diseases

You might guess it'd be tough to extract saliva from a mosquito. And you'd be correct. Yet, because mosquitos spread disease via saliva, it's critical to sample and study.

5 Sep 2024

Is semaglutide use during breastfeeding safe?

Researchers found no detectable levels of semaglutide in breast milk, suggesting minimal risk to breastfed infants, but highlighted the need for monitoring maternal nutrition and milk production.

2 Sep 2024

Exploring OTUB1's influence on protein stability and atherosclerosis pathophysiology

The study investigates the role of the deubiquitinase OTUB1 in vascular smooth muscle cells (VSMCs) within the context of atherosclerosis, a disease characterized by lipid accumulation and plaque formation in arteries.

27 Aug 2024

Engineered human cardiac tissue reveals how lupus autoantibodies damage the heart

Study demonstrates that autoantibodies in systemic lupus erythematosus (SLE) patients contribute to myocardial injury by binding to and impairing stressed cardiac cells, offering insights into potential therapeutic targets.

25 Aug 2024

New analytical method for identifying cancer cell targets

What are the characteristics of a cancer cell that are recognized by the immune system? Knowledge of the potential target structures for the immune cells is a basic prerequisite for the development of personalized cancer immunotherapies. Scientists from the German Cancer Research Center (DKFZ) and the NCT Heidelberg are publishing a highly sensitive method based on mass spectroscopy to identify such tumor-specific "neoepitopes". The analytical method is designed to detect these low-abundance protein fragments and requires minimal amounts of sample material.

23 Aug 2024

The surprising role of RNA in immune interactions

In a groundbreaking exploration of cell surface biology, Ryan Flynn has uncovered a surprising role for RNA outside the confines of the cell. Flynn's research, which focuses on the biology of cell surface RNA, led to the discovery that certain RNAs are chemically linked to glycans - complex carbohydrate polymers found on the cell surface.

22 Aug 2024

Metabolomics links increased heme iron intake to increased insulin-independent type 2 diabetes risk

Researchers utilie metabolomics to investigate the processes underlying dietary heme iron consumption and the risk of type 2 diabetes.

20 Aug 2024

Scientists discover key age-related biological shifts at 40 and 60

Researchers uncover the nonlinear dynamics of aging, revealing significant biological shifts at ages 40 and 60, offering new insights into age-related diseases.

16 Aug 2024

Researchers develop new method to study critical type of protein modification process

Human proteins undergo a variety of chemical modifications following their synthesis. These modifications regulate their structure, function, and stability.

12 Aug 2024

New technique reveals abnormalities in motor neurone disease

Pathological abnormalities associated with motor neurone disease have been identified using a new technique developed at the University of Birmingham.

8 Aug 2024

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

In this interview conducted at Pittcon 2024, we spoke to Professor John Yates about capturing cardiomyocyte cell-to-cell heterogeneity via shotgun top-down proteomics.

From Pittcon 6 Aug 2024

Uncovering hidden drug benefits through protein mapping

Fewer side effects, improved chances of healing: the goal of precision medicine is to provide patients with the most individualized treatment possible. This requires a precise understanding of what is happening at the cellular level. For the first time, researchers at the Technical University of Munich (TUM) have now succeeded in mapping the interactions of 144 active substances with around 8,000 proteins. The results could help to identify previously unknown potential benefits of existing drugs.

2 Aug 2024

Spectrometry News and Research

SCIEX summit - Highlighting scientific breakthroughs in mass spectrometry that really count

Cosmochemistry techniques shed light on potential new Alzheimer's disease biomarker

Researchers uncover connection between two common diabetes drugs with implications for foot ulcer healing

Study reveals how sex hormones regulate immune system functions

Auburn University researchers develop AI-driven method to target cancer proteins

How mosquito spit could help develop therapies for arboviral diseases

Is semaglutide use during breastfeeding safe?

Exploring OTUB1's influence on protein stability and atherosclerosis pathophysiology

Engineered human cardiac tissue reveals how lupus autoantibodies damage the heart

New analytical method for identifying cancer cell targets

The surprising role of RNA in immune interactions

Metabolomics links increased heme iron intake to increased insulin-independent type 2 diabetes risk

Scientists discover key age-related biological shifts at 40 and 60

Researchers develop new method to study critical type of protein modification process

New technique reveals abnormalities in motor neurone disease

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

Uncovering hidden drug benefits through protein mapping

New blood test achieves 90% accuracy in diagnosing Alzheimer’s disease, outperforms doctors

E-Cigarettes and Ethanol: A Forensic Perspective on Vaping

Study investigates the link between an exposome score and metabolic health across childhood

Enhancing confidence in chemical ionization spectrometry data eBook

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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