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Studies reveal how kidney tumors' microenvironments change in response to immunotherapy

In the last two decades, immunotherapy has emerged as a leading treatment for advanced renal carcinoma cancer (more commonly known as kidney cancer).

11 Mar 2021

New SARS-CoV-2 vaccine candidate produces strong immune response, prevents SARS-CoV-2 infection

A new SARS-CoV-2 vaccine candidate, developed by giving a key protein's gene a ride into the body while encased in a measles vaccine, has been shown to produce a strong immune response and prevent SARS-CoV-2 infection and lung disease in multiple animal studies.

10 Mar 2021

New findings could help speed the treatment for UTIs in children

A study led by UT Southwestern and Children's Health researchers defines parameters for the number of white blood cells that must be present in children's urine at different concentrations to suggest a urinary tract infection (UTI).

8 Mar 2021

CAR T-cell therapy triples expected length of remission for relapsed multiple myeloma patients

A new type of CAR T-cell therapy more than triples the expected length of remission for multiple myeloma patients who have relapsed several times, according to an international clinical trial with UT Southwestern as the lead enrolling site.

8 Mar 2021

Study shows macrophages cause excess scarring after surgery

The body is amazing at healing itself. However, sometimes it can overdo it. Excess scarring after abdominal and pelvic surgery within the peritoneal cavity can lead to serious complications and sometimes death.

8 Mar 2021

Biomarkers in the blood can predict severe outcomes in COVID-19 patients

When patients with COVID-19 arrive in emergency rooms, there are relatively few ways for doctors to predict which ones are more likely to become critically ill and require intensive care and which ones are more likely to enjoy a quick recovery.

26 Feb 2021

Innate immune system prevents severe COVID-19 in children

Children are protected from severe COVID-19 because their innate immune system is quick to attack the virus, a new study has found.

17 Feb 2021

Blood-clotting protein linked with tumor pathogenesis of CNS B-cell lymphoma

In people with central nervous system (CNS) lymphoma, cancerous B cells--a type of white blood cell--accumulate to form tumors in the brain or spinal cord, often in close proximity to blood vessels.

17 Feb 2021

$FDA approves cell-based gene therapy to treat adults with relapsed or refractory large-B-cell lymphoma$

FDA approves cell-based gene therapy to treat adults with relapsed or refractory large-B-cell lymphoma

Today, the U.S. Food and Drug Administration approved Breyanzi (lisocabtagene maraleucel), a cell-based gene therapy to treat adult patients with certain types of large B-cell lymphoma who have not responded to, or who have relapsed after, at least two other types of systemic treatment.

5 Feb 2021

Immune dysregulation can affect the efficacy of CAR T therapy in some lymphoma patients

Chimeric antigen receptor T-cell therapy, or CAR T, has been a breakthrough in the treatment of blood cancers such as acute lymphoblastic leukemia and diffuse large B-cell lymphoma.

2 Feb 2021

New maintenance treatment for AML shows strong benefit for patients

Patients with acute myeloid leukemia (AML), the most common form of acute leukemia in adults, that has gone into remission following initial chemotherapy remain in remission longer and have improved overall survival when they are given a pill form of the cancer drug azacitidine as a maintenance treatment, according to a randomized, international phase 3 clinical trial for which Weill Cornell Medicine and NewYork-Presbyterian are trial sites.

22 Jan 2021

Study reveals new insights into how UV light triggers kidney inflammation in lupus patients

A new collaborative study from researchers at the Geisel School of Medicine at Dartmouth and the University of Washington (UW) and published in the Proceedings of the National Academy of Sciences, reveals unexpected insights into how skin exposure to ultraviolet light can worsen clinical symptoms in autoimmune diseases such as lupus.

22 Jan 2021

Researchers measure brain volume differences in HIV-infected individuals

Nearly 38 million people around the world are living with HIV, which, with access to treatment, has become a lifelong chronic condition. Understanding how infection changes the brain, especially in the context of aging, is increasingly important for improving both treatment and quality of life.

16 Jan 2021

Myelin‐specific T cells implicated in central nervous system disease in monkeys

Scientists have uncovered new clues implicating a type of herpes virus as the cause of a central nervous system disease in monkeys that's similar to multiple sclerosis in people.

15 Jan 2021

Study shows why antihistamine drugs fail to control severe itch in eczema patients

In addition to a skin rash, many eczema sufferers also experience chronic itching, but sometimes that itching can become torturous. Worse, antihistamines -- the standard treatment for itching and allergy -- often don't help.

15 Jan 2021

UCSF researchers discover a new way to control immune system's 'natural killer' cells

UC San Francisco scientists have discovered a new way to control the immune system's "natural killer" (NK) cells, a finding with implications for novel cell therapies and tissue implants that can evade immune rejection.

8 Jan 2021

Trinity team uncovers mutations linked with early onset dementia

Scientists at Trinity College Dublin today announced a significant advance in our understanding of an early onset form of dementia that may also progress our understanding of conditions such as Alzheimer's disease.

22 Dec 2020

Study: Structural racism has material impact on health of ethnic minorities, immigrants

Structural racism can lead to discrimination in many aspects of life including criminal justice, employment, housing, health care, political power, and education.

15 Dec 2020

Study shows how STAT5 optimizes function of CD4+ T cells to drive antitumor immunity

Cancer immunotherapy using "designer" immune cells has revolutionized cancer treatment in recent years. In this type of therapy, T cells, a type of white blood cell, are collected from a patient's blood and subjected to genetic engineering to produce T cells carrying a synthetic molecule termed chimeric antigen receptor (CAR) that is designed to enable T cells to recognize and destroy cancer cells.

14 Dec 2020

Pre-existing immunity shapes a person's antibody response to influenza viruses

New research by scientists at the University of Chicago suggests a person's antibody response to influenza viruses is dramatically shaped by their pre-existing immunity, and that the quality of this response differs in individuals who are vaccinated or naturally infected.

11 Dec 2020

White Blood Cell News and Research

Studies reveal how kidney tumors' microenvironments change in response to immunotherapy

New SARS-CoV-2 vaccine candidate produces strong immune response, prevents SARS-CoV-2 infection

New findings could help speed the treatment for UTIs in children

CAR T-cell therapy triples expected length of remission for relapsed multiple myeloma patients

Study shows macrophages cause excess scarring after surgery

Biomarkers in the blood can predict severe outcomes in COVID-19 patients

Innate immune system prevents severe COVID-19 in children

Blood-clotting protein linked with tumor pathogenesis of CNS B-cell lymphoma

FDA approves cell-based gene therapy to treat adults with relapsed or refractory large-B-cell lymphoma

Immune dysregulation can affect the efficacy of CAR T therapy in some lymphoma patients

New maintenance treatment for AML shows strong benefit for patients

Study reveals new insights into how UV light triggers kidney inflammation in lupus patients

Researchers measure brain volume differences in HIV-infected individuals

Myelin‐specific T cells implicated in central nervous system disease in monkeys

Study shows why antihistamine drugs fail to control severe itch in eczema patients

UCSF researchers discover a new way to control immune system's 'natural killer' cells

Trinity team uncovers mutations linked with early onset dementia

Study: Structural racism has material impact on health of ethnic minorities, immigrants

Study shows how STAT5 optimizes function of CD4+ T cells to drive antitumor immunity

Pre-existing immunity shapes a person's antibody response to influenza viruses

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