immunity News and Research

RSS

Gut microbiome changes improve memory in early cognitive decline

Research shows that modifying the gut microbiome can enhance cognitive performance and mitigate dementia risk, highlighting the gut-brain connection.

1 Apr 2026

Aging reshapes breast tissue creating environment favorable for cancer

Scientists have created the most detailed map to date, comprised of over 3 million cells, showing how breast tissue changes as women age – including dramatic changes during menopause.

31 Mar 2026

Innate immunity genes may influence earlier breast cancer onset in BRCA1 carriers

Damaging variants in genes involved in a rapid immune response (innate immunity) are significantly linked to earlier breast cancer onset in carriers of the harmful BRCA1 genetic mutation, reveal preliminary findings published online in the Journal of Medical Genetics.

31 Mar 2026

How the nutrient cysteine controls cancer-fighting power of T cells

A research team from the Johns Hopkins Kimmel Cancer Center, its Bloomberg~Kimmel Institute for Cancer Immunotherapy and the Johns Hopkins Bloomberg School of Public Health have discovered how the immune system's CD8+ T cells use the nutrient cysteine to control two essential functions that compete for this resource - the immune cell's ability to multiply and its ability to kill cancer cells.

31 Mar 2026

New T cell mechanism could lead to longer-lasting vaccines

Researchers at the University of Wisconsin School of Veterinary Medicine have identified a possible way to make longer lasting vaccines for respiratory viruses like influenza and the coronavirus that causes COVID-19.

31 Mar 2026

Gut-derived metabolites regulate immune cells in complex ways

Published on March 23, 2026, in Volume 2, article number 18 of the journal Immunity & Inflammation, the review begins by systematically outlining the sources and synthetic pathways of immune-relevant microbial metabolites, including bile acids, short-chain fatty acids, amino acid derivatives, vitamins, trimethylamine/trimethylamine N-oxide, and odd-chain fatty acids.

31 Mar 2026

Study reveals ALDH2 vulnerability in APC-deficient colorectal cancer

A precision cancer strategy that selectively kills tumour cells while leaving healthy tissue intact may be within reach for the majority of colorectal cancer patients, according to new research published in Genes & Disease.

30 Mar 2026

APOE4 alters brain immunity and cognition differently in females and males

APOE4 drove sex-specific changes in meningeal immunity, lymphatic drainage, brain lipids, neuroinflammation, and cognition in mouse models, with females showing greater inflammatory and cognitive vulnerability. Suppressing innate immunity improved some cognitive outcomes in female E4/E4 mice but worsened them in male E4/E4 mice, underscoring the need for sex-tailored approaches.

29 Mar 2026

Gut immune responses found to trigger brain inflammation in MS

Multiple sclerosis (MS) is a debilitating neurological disorder caused by malfunctioning immune responses that target the brain and spinal cord of the central nervous system (CNS).

27 Mar 2026

Aging lung cells drive severe inflammation in flu and COVID

Older adults are much more likely to become seriously ill from flu or COVID because aging lung cells can drive excessive immune responses, according to a new study led by researchers at UC San Francisco.

27 Mar 2026

Microfluidic chips enable realistic modeling of tumor immune environments

The challenge is that the tumor immune microenvironment is not a static backdrop but a constantly shifting ecosystem shaped by cancer cells, immune cells, stromal cells, cytokines, and physical barriers.

26 Mar 2026

Study explores racial differences in gastric cancer immunotherapy outcomes

Advanced gastric cancer remains one of the deadliest malignancies, with a 5-year overall survival rate below 10%.

26 Mar 2026

New study maps global immune gene diversity across multiple populations

Inherited variations in antibody genes can affect how we respond to infections and vaccines, show two new studies from Karolinska Institutet in Sweden, published in the journal Immunity.

26 Mar 2026

CDC tracks SARS-CoV-2 BA.3.2 global rise and finds early signals in U.S. wastewater

CDC surveillance shows that the highly divergent SARS-CoV-2 variant BA.3.2 spread to at least 23 countries and was detected in U.S. travelers, patients, airplane wastewater, and wastewater samples across multiple states. The report highlights wastewater and traveler-based genomic surveillance as early warning tools while noting that BA.3.2 has immune-evasion potential but has not rapidly displaced other circulating lineages.

25 Mar 2026

Immune cells use neurotransmitters to regulate health and disease

The article, titled "Emerging roles of immune cell-derived neurotransmitters in immunity and disease," published on March 17, 2026, in Immunity & Inflammation, provides a timely and authoritative review of how innate and adaptive immune cells-including macrophages, dendritic cells, natural killer cells, T cells, and B cells-produce and respond to classic neurotransmitters.

25 Mar 2026

Systematic review identifies stress-induced biological triggers in oncology

Stress is a constant companion in the oncologist's office. It appears at the time of diagnosis, increases with each stage of treatment, and often does not resolve even after therapy formally ends. It accompanies therapeutic decisions, waiting for test results, fear of recurrence, and changes in daily functioning. Studies show that chronic stress can trigger biological processes that promote disease progression and weaken the body's defenses.

25 Mar 2026

Breakthrough research reshapes understanding of T cell immune responses

In a paradigm breaking study, Dr. Pavan Reddy, director of the Dan L Duncan Comprehensive Cancer Center at Baylor College of Medicine (BCM) and his team, in collaboration with Drs. Arul Chinnaiyan, S P Hicks Endowed Professor of Pathology, and Marcin Cieslik, assistant professor of pathology, both from University of Michigan Rogel Cancer Center, discovered a novel way the immune system, specifically T-cells, attack their target cells, reshaping long-held assumptions in immunology and demonstrating direct implications for the field of cancer immunology and bone marrow transplantation.

24 Mar 2026