Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

COVID-19 – researchers sum up the “Tsunami” of information

The severe acute respiratory syndrome coronavirus 2 (SARS CoV-2) infection leading to COVID-19 is a raging pandemic across the world at present. It has infected 13 million and killed 571,000 individuals around the world as of today. The infection was first reported in Wuhan, Hubei Province of China in late December 2019.

13 Jul 2020

Study shows safety and effectiveness of PET radiotracer in imaging glioblastomas

A first-in-human study presented at the Society of Nuclear Medicine and Molecular Imaging 2020 Annual Meeting has demonstrated the safety, favorable pharmacokinetic and dosimetry profile of 64Cu-EBRGD, a new, relatively long-lived PET tracer, in patients with glioblastomas.

13 Jul 2020

Long-studied protein can be used as biomarker for traumatic brain injury

Scientists at the Walter Reed Army Institute for Research have recently demonstrated that cathepsin B, a well-studied protein important to brain development and function, can be used as biomarker, or indicator of severity, for traumatic brain injury.

13 Jul 2020

Apathy not depression offers an important early warning sign of dementia

Apathy offers an important early warning sign of dementia in individuals with cerebrovascular disease, but depression does not, new research led by the University of Cambridge suggests.

13 Jul 2020

Scientists recommend a decentralized biosurveillance system to protect from diseases

The emergence of COVID-19 is a powerful reminder of how unchecked wildlife trade can lead to the spillover spread of viruses between wildlife and humans.

10 Jul 2020

Expansion stress promotes aggressive tumor cell growth in breast cancer

Expansion stress can have an alarming impact on breast cancer cells by creating conditions that could lead to dangerous acceleration of the disease, an interdisciplinary team of University of Alabama at Birmingham researchers has found.

9 Jul 2020

UNM study sheds new light on transition of fear to anxiety

A deadly coronavirus pandemic, economic instability and civil unrest menace the mental well-being of millions.

9 Jul 2020

DNA hypermethylation correlated with reduced amygdala volume in male patients with schizophrenia

Researchers at Kumamoto University, Japan have revealed that DNA methylation occurs in the gene that codes serotonin transporter (SERT), a protein that regulates neurotransmitter transmission, in schizophrenia and bipolar patients.

9 Jul 2020

ACTIONED consortium aims to transform future treatment of colorectal cancer patients

The Precision Medicine Centre of Excellence (PMC) at Queen's is leading a ground-breaking collaboration with the world's largest biotech company Roche, and Artificial Intelligence (AI) specialist, Sonrai Analytics.

9 Jul 2020

Blocking tumor-promoting protein could bolster immunotherapy's effectiveness, study suggests

While immunotherapy -- a form of treatment that uses the body's immune system to recognize, attack and kill tumor cells -- has given hope to people across the globe, it fails in a significant proportion of cancer patients.

8 Jul 2020

Study reveals how overactive immune cells aggravate heart valve disease

A new study using organ-on-a-chip technology reveals how overactive immune cells aggravate heart valve disease and how this damaging hyperactivity could potentially be controlled.

8 Jul 2020

Gene expression networks flag potential therapeutic targets for SARS-CoV-2

An international team of researchers from Canada, Australia, the Netherlands, and the United States has identified dozens of genes that could contribute to the pathology of coronavirus disease 2019 (COVID-19) and serve as potential therapeutic targets.

7 Jul 2020

New web-based tool could contribute to the development of better cancer treatments

The results are now published in Nature Medicine and at the same time the tool - the Molecular Tumor Board Portal - will be launched on www.mtbp.org. Janne Lehtiö, professor at the Karolinska Institutet Department of Oncology-Pathology led this work, along with researcher David Tamborero.

7 Jul 2020

New technique to sort out complex interactions unique to prostate cancer cells

UT Southwestern researchers have identified vast webs of small snippets of the genome that interact with each other and with genes to promote prostate cancer.

7 Jul 2020

Faulty immune response to SARS-CoV-2 one of the main causes of death

A new study published on the preprint server medRxiv in July 2020 describes the organ and tissue-specific spread of the virus causing the current COVID-19 pandemic, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

7 Jul 2020

Study shows how non-alcoholic fatty liver disease causes Alzheimer's-like neuroinflammation

Research from University of South Carolina associate professor Saurabh Chatterjee's laboratory in Environmental Health Sciences, Arnold School of Public Health, and led by Ayan Mondal, a postdoctoral researcher from the same lab, has revealed the cause behind the previously established link between non-alcoholic fatty liver disease (i.e., NAFLD, recently reclassified as metabolic associated fatty liver disease or MAFLD) and neurological problems.

6 Jul 2020

Novel cell-based approach used to reverse age-related impairments in animal model

Elderly people are more prone to infectious diseases as the function of their immune system continuously declines with progression of age.

6 Jul 2020

Human trials of potential COVID-19 vaccine commence in South Australia

A potential COVID-19 vaccine developed at Flinders University has commenced human trials in South Australia.

6 Jul 2020

Using machine learning to analyze the interaction of breast cancer risk factors

A recently published article from University of Eastern Finland and Kuopio University Hospital reports new innovative use of machine learning to help understand the interplay of genetic and other breast cancer risk factors.

6 Jul 2020

Researchers isolate protective antibodies for rare, polio-like disease in children

Researchers at Vanderbilt University Medical Center, Purdue University and the University of Wisconsin-Madison have isolated human monoclonal antibodies that potentially can prevent a rare but devastating polio-like illness in children linked to a respiratory viral infection.

3 Jul 2020

Pathology News and Research

Further Reading

COVID-19 – researchers sum up the “Tsunami” of information

Study shows safety and effectiveness of PET radiotracer in imaging glioblastomas

Long-studied protein can be used as biomarker for traumatic brain injury

Apathy not depression offers an important early warning sign of dementia

Scientists recommend a decentralized biosurveillance system to protect from diseases

Expansion stress promotes aggressive tumor cell growth in breast cancer

UNM study sheds new light on transition of fear to anxiety

DNA hypermethylation correlated with reduced amygdala volume in male patients with schizophrenia

ACTIONED consortium aims to transform future treatment of colorectal cancer patients

Blocking tumor-promoting protein could bolster immunotherapy's effectiveness, study suggests

Study reveals how overactive immune cells aggravate heart valve disease

Gene expression networks flag potential therapeutic targets for SARS-CoV-2

New web-based tool could contribute to the development of better cancer treatments

New technique to sort out complex interactions unique to prostate cancer cells

Faulty immune response to SARS-CoV-2 one of the main causes of death

Study shows how non-alcoholic fatty liver disease causes Alzheimer's-like neuroinflammation

Novel cell-based approach used to reverse age-related impairments in animal model

Human trials of potential COVID-19 vaccine commence in South Australia

Using machine learning to analyze the interaction of breast cancer risk factors

Researchers isolate protective antibodies for rare, polio-like disease in children

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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