Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

UC Davis participates in landmark study to test whether lifestyle changes can prevent cognitive decline

UC Davis Alzheimer's Disease Center and Department of Public Health Sciences has received $6 million to participate in a landmark study that will see if multiple changes in lifestyle can protect against changes in memory and thinking in older adults.

19 Jul 2019

Alzheimer's gene may affect cognitive health before adulthood, study finds

The Apolipoprotein E (APOE) is a major cholesterol carrier that aids in lipid transport and injury repair in the brain. It packages cholesterol and other fats and moves them through the bloodstream. APOE polymorphic alleles are the major genetic factors for the risk of Alzheimer’s disease (AD).

19 Jul 2019

Researchers identify brain somatic mutations linked to Alzheimer's disease

Researchers have identified somatic mutations in the brain that could contribute to the development of Alzheimer's disease. Their findings were published in the journal Nature Communications last week.

18 Jul 2019

Common medications can masquerade as dementia in seniors

By all accounts the woman, in her late 60s, appeared to have severe dementia. She was largely incoherent. Her short-term memory was terrible. She couldn't focus on questions that medical professionals asked her.

18 Jul 2019

Light at last: why do more women develop Alzheimer’s disease?

Alzheimer’s disease (AD) is a leading cause of dementia in many older people, but it seems to affect twice as many women as men. Scientists have long tried to find out why this is so, and why it seems to follow a fast-track course in women.

18 Jul 2019

Human genotype determines if a given Alzheimer's drug will be effective

University at Buffalo researchers have determined that a human gene present in 75 % of the population is a key reason why a class of drugs for Alzheimer's disease seemed promising in animal studies only to fail in human studies.

18 Jul 2019

Study finds sex-specific differences in risk and progression of Alzheimer's disease

The abnormal accumulation of proteins in the brain is a biological marker for Alzheimer's disease, but the ways in which these proteins spread may help explain why the prevalence of Alzheimer's is higher in women than in men.

16 Jul 2019

Researchers use blood samples from zoo to improve computer-assisted disease prognosis

The researchers want to use similar genetic patterns, which have been present in the blood of humans and animals for thousands of years, to improve computer-assisted disease prognosis.

16 Jul 2019

Researchers discover new therapeutic target for treatment of Alzheimer's disease

Experiments performed in mice, in which the main pathogenic markers of the disease have been evaluated, show that the progression of the disease is prevented when the function of this protein is inactivated.

15 Jul 2019

New app created to help people reduce exposure to anticholinergic medications

A team of researchers from Indiana University School of Medicine, Regenstrief Institute and Purdue University, led by Richard Holden, PhD, is testing a new app, called Brain Safe, designed to help people reduce their exposure to a common class of drugs linked to Alzheimer's disease.

15 Jul 2019

Healthy lifestyle lowers dementia risk despite genetic predisposition

Having a healthy lifestyle doesn’t only help you lose weight, but it may also offset the genetic risk in developing dementia, a new study published in JAMA found.

15 Jul 2019

An active brain and body associated with reduced risk of dementia

A team of researchers at the Tianjin Medical University in China wanted to explore whether accumulation over a lifetime of cognitive and social activities are linked to a slower rate of memory loss, hence, a lower risk of developing dementia, despite brain pathologies.

14 Jul 2019

Researchers open the door to a new era of medicinal chemistry

Progress in the pharmaceutical industry depends largely on the achievements and advances in medicinal chemistry.

14 Jul 2019

A program of therapy and coping strategies works long-term for family dementia carers

A program of therapy and coping strategies for people who care for family members with dementia successfully improves the carers' mental health for at least a six-year follow-up, finds a UCL study.

12 Jul 2019

Study offers clues about how to prevent brain inflammation in Alzheimer's

A new study by scientists at Massachusetts General Hospital offers clues about how to prevent inflammation of brain tissue, which promotes Alzheimer's disease

11 Jul 2019

Quanterix to convene leading industry researchers at Alzheimer’s Association International Conference 2019 following closing of UmanDiagnostics acquisition

Quanterix marks major milestones as it continues to expand its footprint in neurology and lead the digital biomarker revolution across healthcare.

From Quanterix 11 Jul 2019

Mentally stimulating activities linked to lower risk or delay of age-related memory loss

A new study has found that mentally stimulating activities like using a computer, playing games, crafting and participating in social activities are linked to a lower risk or delay of age-related memory loss called mild cognitive impairment, and that the timing and number of these activities may also play a role.

11 Jul 2019

Computers, games, crafting keep the aging brain sharp

A team of researchers wanted to investigate whether timing, number, and frequency of brain-stimulating activities in midlife and late life are linked to the risk of incident mild cognitive impairment (MCI).

11 Jul 2019

Study highlights the need for larger Alzheimer's drug trials that intervene much earlier

There are currently no drugs that stop or inhibit Alzheimer's disease. Despite drug trials showing plaque reduction in the brain, the patients' cognitive function did not improve.

11 Jul 2019

Adults with family history of Alzheimer’s have learning impairments, study finds

Adults with a first-degree relative with Alzheimer's disease perform more poorly on online paired-learning tasks than adults without such a family history, and this impairment appears to be exacerbated by having diabetes or a genetic variation in the apolipoprotein E (APOE) gene linked to the disease.

10 Jul 2019

Alzheimer's Disease News and Research

Further Reading

UC Davis participates in landmark study to test whether lifestyle changes can prevent cognitive decline

Alzheimer's gene may affect cognitive health before adulthood, study finds

Researchers identify brain somatic mutations linked to Alzheimer's disease

Common medications can masquerade as dementia in seniors

Light at last: why do more women develop Alzheimer’s disease?

Human genotype determines if a given Alzheimer's drug will be effective

Study finds sex-specific differences in risk and progression of Alzheimer's disease

Researchers use blood samples from zoo to improve computer-assisted disease prognosis

Researchers discover new therapeutic target for treatment of Alzheimer's disease

New app created to help people reduce exposure to anticholinergic medications

Healthy lifestyle lowers dementia risk despite genetic predisposition

An active brain and body associated with reduced risk of dementia

Researchers open the door to a new era of medicinal chemistry

A program of therapy and coping strategies works long-term for family dementia carers

Study offers clues about how to prevent brain inflammation in Alzheimer's

Quanterix to convene leading industry researchers at Alzheimer’s Association International Conference 2019 following closing of UmanDiagnostics acquisition

Mentally stimulating activities linked to lower risk or delay of age-related memory loss

Computers, games, crafting keep the aging brain sharp

Study highlights the need for larger Alzheimer's drug trials that intervene much earlier

Adults with family history of Alzheimer’s have learning impairments, study finds

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